Terpurinflavone: An antiplasmodial flavone from the stem of Tephrosia Purpurea

Phytochemistry Letters

Volumn 4, Issue 2, 2011, Pages 176-178

  Juma, Wanyama P ^a   Akala, Hoseah M ^b   Eyase, Fredrick L ^b,c   Muiva, Lois M ^a   Heydenreich, Matthias ^d   Okalebo, Faith A ^a   Gitu, Peter M ^a   Peter, Martin G ^d   Walsh, Douglas S ^b   Imbuga, Mabel ^c   Yenesew, Abiy ^a  

^a UNIVERSITY OF NAIROBI   (Kenya)

^b U S ARMY   (United States)

^c JOMO KENYATTA UNIVERSITY OF AGRICULTURE AND TECHNOLOGY   (Kenya)

^d UNIVERSITY OF POTSDAM   (Germany)

Author keywords

Antiplasmodial; Flavone; Leguminosae; Stem; Tephrosia purpurea; Terpurinflavone

Indexed keywords

ANTIMALARIAL AGENT; CHLOROQUINE; FLAVONE DERIVATIVE; LANCEOLATIN; LANCEOLATIN A; MEFLOQUINE; PLANT EXTRACT; SEMIGLABRIN; TERPURINFLAVONE; UNCLASSIFIED DRUG;

ANTIBIOTIC SENSITIVITY; ANTIMALARIAL ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; DRUG DETERMINATION; DRUG ISOLATION; DRUG STRUCTURE; ELECTROSPRAY; FLUOROCHROME STAINING; IC 50; IN VITRO STUDY; MEDICINAL PLANT; NONHUMAN; PLANT STEM; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; TEPHROSIA; TEPHROSIA PURPUREA; TIME OF FLIGHT MASS SPECTROMETRY;

FABACEAE; PLASMODIUM FALCIPARUM; TEPHROSIA PURPUREA;

EID: 79957523115     PISSN: 18743900     EISSN: 18767486     Source Type: Journal    
DOI: 10.1016/j.phytol.2011.02.010     Document Type: Article

References (17)

1. A.M. Abou-Douh, C. Ito, R.A. Toscano, N.Y. El-Baga, E.A. El-Khrisy, and H. Furukawa Prenylated flavonoids from the roots of Egyptian Tephrosia apollinea-crystal structure analysis Z. Naturforsch. 60b 2005 458 470 (Pubitemid 40726728)
2. V.U. Ahmad, Z. Ali, S.R. Hussaini, F. Iqbal, M. Zahid, M. Abbas, and N. Saba Flavonoids of Tephrosia purpurea Fitoterapia 70 1999 443 445 (Pubitemid 29422650)
3. G. Auffret, M. Labaied, F. Frappier, P. Rasoanaivo, P. Grellier, and G. Lewin Synthesis and antimalarial evaluation of a series of piperazinyl flavones Bioorg. Med. Chem. Lett. 17 2007 959 963 (Pubitemid 46188532)
4. L.C. Chang, D. Chavez, L.L. Song, N.R. Farnsworth, J.M. Pezzuto, and A.D. Kinghorn Absolute configuration of novel bioactive flavonoids from Tephrosia purpurea Org. Lett. 2 2000 515 518
5. A. Chinniah, S. Mohapatra, S. Goswami, A. Mahapatra, S.K. Kar, U.V. Mallavadhani, and P.K. Das On the potential of Tephrosia purpurea as anti-Helicobacter pylori agent J. Ethnopharmacol. 124 2009 642 645
6. A.S. Damre, A.B. Gokhale, A.S. Phadke, K.R. Kulkarini, and M.N. Saraf Studies on immunomodulatory activity of flavonoidal fraction of Tephrosia purpurea Fitoterapia 74 2003 515 518
7. N.E. Delfel, W.H. Tallent, D.G. Carlson, and I.A. Wolff Distribution of rotenone and deguelin in tephrosia vogelii and separation of rotenoid-rich fractions J. Agric. Food Chem. 18 1970 385 390
8. R.K. Gupta, M. Krishnamurti, and J. Parthasarathi Purpurin, a flavanone from Tephrosia purpurea seeds Phytochemistry 19 1980 1264
9. M.-E.F. Hegazy, M.H. Abd El-Razek, Y. Asakawa, and P.W. Par'e Rare prenylated flavonoids from Tephrosia purpurea Phytochemistry 70 2009 1474 1477
10. J.D. Johnson, R.A. Dennull, L. Gerena, M. Lopez-Sanchez, N.E. Roncal, and N.C. Waters Assessment and continued validation of malaria SYBR green I-based fluorescence assay for use in malaria drug screening Antimicrob. Agents Chemother. 51 2007 1926 1933 (Pubitemid 46903075)
11. L.M. Muiva, A. Yenesew, S. Derese, M. Heydenreich, M.G. Peter, H.M. Akala, F. Eyase, N.C. Waters, C. Mutai, J.M. Keriko, and D. Walsh Antiplasmodial β-hydroxydihydrochalcone from the seeds of Tephrosia elata Phytochemistry Lett. 2 2009 99 102
12. P. Pavana, S. Sethupathy, K. Santha, and S. Manoharan Effects of Tephrosia purpurea aqueous seed extract on blood glucose and antioxidant enzyme activities in streptozotocin induced diabetic rats Afr. J. Tradit. Complement. Altern. Med. 6 2009 78 86
13. A. Pelter, R.S. Ward, E.V. Rao, and N.R. Raju 8-Substituted Flavonoids and 3′-substituted 7-Oxygenated chalcones from Tephrosia purpurea J. Chem. Soc. Perkin I 1981 2491 2998
14. L. Santram, P.R. Singh, J.A. Pal, and A.K. Singhai Wound healing potential of Tephrosia purpurea (Linn.) pers. in rats J. Ethnopharmacol. 108 2006 204 210 (Pubitemid 44635026)
15. M. Smilkstein, N. Sriwilaijaroen, J.X. Kelly, P. Wilairat, and M. Riscoe Simple and inexpensive fluorescence-based technique for high-throughput antimalarial drug screening Antimicrob. Agents Chemother. 48 2004 1803 1806 (Pubitemid 38544392)
16. P.K. Tarus, A.K. Machocho, C.C. Lang'at-Thoruwa, and S.C. Chhabra Flavonoids from Tephrosia aequilata Phytochemistry 60 2002 375 379 (Pubitemid 34619889)
17. P.G. Waterman, and A.S. Khalid The major flavonoids of the seeds of Tephrosia apollinea Phytochemistry 19 1980 909 915