Evaluation of a novel poly N-acetyl glucosamine (pGlcNAc) hydrogel for treatment of the degenerating intervertebral disc

Life Sciences

Volumn 91, Issue 25-26, 2012, Pages 1328-1335

  Gorapalli, Deepthi ^a,d   Seth, Arun ^b   Vournakis, John ^c   Whyne, Cari ^a   Akens, Margarete ^a   Zhang, Aiguo ^b   Demcheva, Marina ^c   Qamirani, Erion ^a   Yee, Albert ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b SUNNYBROOK RESEARCH INSTITUTE   (Canada)

^c Marine Polymer Technologies Inc   (United States)

^d Abbot Inc   (United States)

Author keywords

Disc degeneration; Glucosamine; Hydrogel; Intervertebral disc

Indexed keywords

AGGRECAN; COLLAGEN TYPE 2; N ACETYLGLUCOSAMINE; NANOFIBER; PROTEOGLYCAN; SCLEROPROTEIN;

ARTICLE; BIOLOGICAL ACTIVITY; BIOMECHANICS; CELL METABOLISM; CELL PROLIFERATION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEACETYLATION; DRUG EFFECT; DRUG FORMULATION; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HUMAN TISSUE; HYDRATION; HYDROGEL; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; INTERVERTEBRAL DISK DEGENERATION; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VISCOELASTICITY;

ACETYLGLUCOSAMINE; ADULT; CELL SURVIVAL; COLLAGEN TYPE II; DIATOMS; ELASTICITY; EXTRACELLULAR MATRIX; FEMALE; HUMANS; HYDROGELS; INTERVERTEBRAL DISC; MALE; MIDDLE AGED; PROTEOGLYCANS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TISSUE ENGINEERING; VISCOSITY;

NITZSCHIA ALBA;

EID: 84870295172     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2012.10.014     Document Type: Article

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