-
5
-
-
0035101515
-
CD28-B7-mediated T cell costimulation in chronic cardiac allograft rejection: Differential role of B7-1 in initiation versus progression of graft arteriosclerosis
-
Kim KS, Denton MD, Chandraker A, et al. CD28-B7-mediated T cell costimulation in chronic cardiac allograft rejection: differential role of B7-1 in initiation versus progression of graft arteriosclerosis. Am J Pathol 2001; 158:977-986. (Pubitemid 32221789)
-
(2001)
American Journal of Pathology
, vol.158
, Issue.3
, pp. 977-986
-
-
Kim, K.S.1
Denton, M.D.2
Chandraker, A.3
Knoflach, A.4
Milord, R.5
Waaga, A.M.6
Turka, L.A.7
Russell, M.E.8
Peach, R.9
Sayegh, M.H.10
-
6
-
-
0029871741
-
The in vivo mechanism of action of CTLA4Ig
-
Judge TA, Tang A, Spain LM, et al. The in vivo mechanism of action of CTLA4Ig. J Immunol 1996; 156:2294-2299. (Pubitemid 26087460)
-
(1996)
Journal of Immunology
, vol.156
, Issue.6
, pp. 2294-2299
-
-
Judge, T.A.1
Tang, A.2
Spain, L.M.3
Gratiot-Deans, J.4
Sayegh, M.H.5
Turka, L.A.6
-
7
-
-
20044386299
-
Rational development of LEA29Y (belatacept), a high-affinity variant of CTLA4-Ig with potent immunosuppressive properties
-
DOI 10.1111/j.1600-6143.2005.00749.x
-
Larsen CP, Pearson TC, Adams AB, et al. Rational development of LEA29Y (belatacept), a high-affinity variant of CTLA4-Ig with potent immunosuppressive properties. Am J Transplant 2005; 5:443-453. (Pubitemid 40313335)
-
(2005)
American Journal of Transplantation
, vol.5
, Issue.3
, pp. 443-453
-
-
Larsen, C.P.1
Pearson, T.C.2
Adams, A.B.3
Tso, P.4
Shirasugi, N.5
Strobert, E.6
Anderson, D.7
Cowan, S.8
Price, K.9
Naemura, J.10
Emswiler, J.11
Greene, J.12
Turk, L.A.13
Bajorath, J.14
Townsend, R.15
Hagerty, D.16
Linsley, P.S.17
Peach, R.J.18
-
8
-
-
0026738641
-
Long-term survival of xenogeneic pancreatic islet grafts induced by CTLA4lg
-
Lenschow DJ, Zeng Y, Thistlethwaite JR, et al. Long-term survival of xenogeneic pancreatic islet grafts induced by CTLA4lg. Science 1992; 257:789-792.
-
(1992)
Science
, vol.257
, pp. 789-792
-
-
Lenschow, D.J.1
Zeng, Y.2
Thistlethwaite, J.R.3
-
9
-
-
65549169583
-
Assessment of belatacept-mediated costimulation blockade through evaluation of CD80/86-receptor saturation
-
et al.
-
Latek R, Fleener C, Lamian V, et al. Assessment of belatacept-mediated costimulation blockade through evaluation of CD80/86-receptor saturation.; et al. Transplantation 2009; 87:926-933.
-
(2009)
Transplantation
, vol.87
, pp. 926-933
-
-
Latek, R.1
Fleener, C.2
Lamian, V.3
-
10
-
-
24944498854
-
Abatacept for rheumatoid arthritis refractory to tumor necrosis factor α inhibition
-
DOI 10.1056/NEJMoa050524
-
Genovese MC, Becker JC, Schiff M, et al. Abatacept for rheumatoid arthritis refractory to tumor necrosis factor alpha inhibition. N Engl J Med 2005; 353:1114-1123. (Pubitemid 41317434)
-
(2005)
New England Journal of Medicine
, vol.353
, Issue.11
, pp. 1114-1123
-
-
Genovese, M.C.1
Becker, J.-C.2
Schiff, M.3
Luggen, M.4
Sherrer, Y.5
Kremer, J.6
Birbara, C.7
Box, J.8
Natarajan, K.9
Nuamah, I.10
Li, T.11
Aranda, R.12
Hagerty, D.T.13
Dougados, M.14
-
11
-
-
0242574700
-
Treatment of rheumatoid arthritis by selective inhibition of T-cell activation with fusion protein CTLA4Ig
-
DOI 10.1056/NEJMoa035075
-
Kremer JM, Westhovens R, Leon M, et al. Treatment of rheumatoid arthritis by selective inhibition of T-cell activation with fusion protein CTLA4Ig. N Engl J Med 2003; 349:1907-1915. (Pubitemid 37409707)
-
(2003)
New England Journal of Medicine
, vol.349
, Issue.20
, pp. 1907-1915
-
-
Kremer, J.M.1
Westhovens, R.2
Leon, M.3
Di Giorgio, E.4
Alten, R.5
Steinfeld, S.6
Russell, A.7
Dougados, M.8
Emery, P.9
Nuamah, I.F.10
Williams, G.R.11
Becker, J.-C.12
Hagerty, D.T.13
Moreland, L.W.14
-
12
-
-
84870250665
-
Successful long-term patient and renal allograft outcomes after abatacept conversion
-
Stephens NATS
-
Stephens NATS. Successful long-term patient and renal allograft outcomes after abatacept conversion. Am J Transplant 2012; 12 (Suppl 3):300.
-
(2012)
Am J Transplant
, vol.12
, Issue.SUPPL. 3
, pp. 300
-
-
-
13
-
-
23944502334
-
Costimulation blockade with belatacept in renal transplantation
-
DOI 10.1056/NEJMoa050085
-
Vincenti F, Larsen C, Durrbach A, et al. Costimulation blockade with bela-tacept in renal transplantation. N Engl J Med 2005; 353:770-781. (Pubitemid 41215486)
-
(2005)
New England Journal of Medicine
, vol.353
, Issue.8
, pp. 770-781
-
-
Vincenti, F.1
Larsen, C.2
Durrbach, A.3
Wekerle, T.4
Nashan, B.5
Blancho, G.6
Lang, P.7
Grinyo, J.8
Halloran, P.F.9
Solez, K.10
Hagerty, D.11
Levy, E.12
Zhou, W.13
Natarajan, K.14
Charpentier, B.15
-
14
-
-
76949101581
-
A phase III study of belatacept-based immunosuppression regimens versus cyclosporine in renal transplant recipients (BENEFIT study)
-
Vincenti F, Charpentier B, Vanrenterghem Y, et al. A phase III study of belatacept-based immunosuppression regimens versus cyclosporine in renal transplant recipients (BENEFIT study). Am J Transplant 2010; 10:535-546.
-
(2010)
Am J Transplant
, vol.10
, pp. 535-546
-
-
Vincenti, F.1
Charpentier, B.2
Vanrenterghem, Y.3
-
15
-
-
80052901571
-
Challenges and opportunities in targeting the costimulation pathway in solid organ transplantation
-
Wojciechowski D, Vincenti F. Challenges and opportunities in targeting the costimulation pathway in solid organ transplantation. Semin Immunol 2011; 23:157-64.
-
(2011)
Semin Immunol
, vol.23
, pp. 157-164
-
-
Wojciechowski, D.1
Vincenti, F.2
-
16
-
-
84855939763
-
Three-year outcomes from BENEFIT, a randomized, active-controlled, parallel-group study in adult kidney transplant recipients
-
Vincenti F, Larsen CP, Alberu J, et al. Three-year outcomes from BENEFIT, a randomized, active-controlled, parallel-group study in adult kidney transplant recipients. Am J Transplant 2012; 12:210-217.
-
(2012)
Am J Transplant
, vol.12
, pp. 210-217
-
-
Vincenti, F.1
Larsen, C.P.2
Alberu, J.3
-
17
-
-
78650831358
-
Belatacept-based regimens versus a cyclosporine A-based regimen in kidney transplant recipients: 2-year results from the BENEFIT and BENEFIT-EXT studies
-
Larsen CP, Grinyo J, Medina-Pestana J, et al. Belatacept-based regimens versus a cyclosporine A-based regimen in kidney transplant recipients: 2-year results from the BENEFIT and BENEFIT-EXT studies. Transplantation 2010; 90:1528-1535.
-
(2010)
Transplantation
, vol.90
, pp. 1528-1535
-
-
Larsen, C.P.1
Grinyo, J.2
Medina-Pestana, J.3
-
18
-
-
76949090842
-
A phase III study of belatacept versus cyclosporine in kidney transplants from extended criteria donors (BENEFIT-EXT study)
-
Durrbach A, Pestana JM, Pearson T, et al. A phase III study of belatacept versus cyclosporine in kidney transplants from extended criteria donors (BENEFIT-EXT study). Am J Transplant 2010; 10:547-557.
-
(2010)
Am J Transplant
, vol.10
, pp. 547-557
-
-
Durrbach, A.1
Pestana, J.M.2
Pearson, T.3
-
19
-
-
84857646161
-
Three-year outcomes from BENEFIT-EXT: A phase III study of belatacept versus cyclosporine in recipients of extended criteria donor kidneys
-
Pestana JO, Grinyo JM, Vanrenterghem Y, et al. Three-year outcomes from BENEFIT-EXT: a phase III study of belatacept versus cyclosporine in recipients of extended criteria donor kidneys. Am J Transplant 2012; 12:630-639.
-
(2012)
Am J Transplant
, vol.12
, pp. 630-639
-
-
Pestana, J.O.1
Grinyo, J.M.2
Vanrenterghem, Y.3
-
20
-
-
79955544132
-
Belatacept-based regimens are associated with improved cardiovascular and metabolic risk factors compared with cyclosporine in kidney transplant recipients (BENEFIT and BENEFIT-EXT studies)
-
Vanrenterghem Y, Bresnahan B, Campistol J, et al. Belatacept-based regimens are associated with improved cardiovascular and metabolic risk factors compared with cyclosporine in kidney transplant recipients (BENEFIT and BENEFIT-EXT studies). Transplantation 2011; 91:976-983.
-
(2011)
Transplantation
, vol.91
, pp. 976-983
-
-
Vanrenterghem, Y.1
Bresnahan, B.2
Campistol, J.3
-
21
-
-
84864465934
-
Cardiovascular risk calculator for renal transplant recipients: Applications to BENEFIT and BENEFIT-EXT trials
-
Holdas H, Holme I, Jardine A, et al. Cardiovascular Risk Calculator for Renal Transplant Recipients: Applications to BENEFIT and BENEFIT-EXT Trials. Am J Transplant 2012; 12 (Suppl 3):409.
-
(2012)
Am J Transplant
, vol.12
, Issue.SUPPL. 3
, pp. 409
-
-
Holdas, H.1
Holme, I.2
Jardine, A.3
-
22
-
-
84866284135
-
Improvement in renal function in kidney transplant recipients switched from cyclosporine or tacrolimus to belatacept: 2-year results from the long-term extension of a phase II study
-
Grinyo J, Alberu J, Contieri FL, et al. Improvement in renal function in kidney transplant recipients switched from cyclosporine or tacrolimus to belatacept: 2-year results from the long-term extension of a phase II study. Transpl Int 2012.
-
(2012)
Transpl Int
-
-
Grinyo, J.1
Alberu, J.2
Contieri, F.L.3
-
23
-
-
79951933190
-
Switching from calcineurin inhibitor-based regimens to a belatacept-based regimen in renal transplant recipients: A randomized phase II study
-
Rostaing L, Massari P, Garcia VD, et al. Switching from calcineurin inhibitor-based regimens to a belatacept-based regimen in renal transplant recipients: a randomized phase II study. Clin J Am Soc Nephrol 2011; 6:430-439.
-
(2011)
Clin J Am Soc Nephrol
, vol.6
, pp. 430-439
-
-
Rostaing, L.1
Massari, P.2
Garcia, V.D.3
-
24
-
-
65249160252
-
Reducing de novo donor-specific antibody levels during acute rejection diminishes renal allograft loss
-
Everly MJ, Everly JJ, Arend LJ, et al. Reducing de novo donor-specific antibody levels during acute rejection diminishes renal allograft loss. Am J Transplant 2009; 9:1063-1071.
-
(2009)
Am J Transplant
, vol.9
, pp. 1063-1071
-
-
Everly, M.J.1
Everly, J.J.2
Arend, L.J.3
-
25
-
-
40849119814
-
Influence of time of rejection on long-term graft survival in renal transplantation
-
DOI 10.1097/TP.0b013e3181661695, PII 0000789020080315000001
-
Opelz G, Dohler B. Influence of time of rejection on long-term graft survival in renal transplantation. Transplantation 2008; 85:661-666. (Pubitemid 351398238)
-
(2008)
Transplantation
, vol.85
, Issue.5
, pp. 661-666
-
-
Opelz, G.1
Dohler, B.2
-
26
-
-
10744233377
-
Antibody-mediated rejection criteria - An addition to the Banff '97 classification of renal allograft rejection
-
DOI 10.1034/j.1600-6143.2003.00072.x
-
Racusen LC, Colvin RB, Solez K, et al. Antibody-mediated rejection criteria: an addition to the Banff 97 classification of renal allograft rejection. Am J Transplant 2003; 3:708-714. (Pubitemid 36745243)
-
(2003)
American Journal of Transplantation
, vol.3
, Issue.6
, pp. 708-714
-
-
Racusen, L.C.1
Colvin, R.B.2
Solez, K.3
Mihatsch, M.J.4
Halloran, P.F.5
Campbell, P.M.6
Cecka, M.J.7
Cosyns, J.P.8
Demetris, A.J.9
Fishbein, M.C.10
Fogo, A.11
Furness, P.12
Gibson, I.W.13
Glotz, D.14
Hayry, P.15
Hunsickern, L.16
Kashgarian, M.17
Kerman, R.18
Magil, A.J.19
Montgomery, R.20
Morozumi, K.21
Nickeleit, V.22
Randhawa, P.23
Regele, H.24
Seron, D.25
Seshan, S.26
Sund, S.27
Trpkov, K.28
more..
-
27
-
-
12144290610
-
Correlation between the Banff 97 classification of renal allograft biopsies and clinical outcome
-
DOI 10.1007/s00147-003-0660-9
-
Tanaka T, Kyo M, Kokado Y, et al. Correlation betweenthe Banff97classification of renal allograft biopsies and clinical outcome. Transpl Int 2004; 17:59-64. (Pubitemid 38315867)
-
(2004)
Transplant International
, vol.17
, Issue.2
, pp. 59-64
-
-
Tanaka, T.1
Kyo, M.2
Kokado, Y.3
Takahara, S.4
Hatori, M.5
Suzuki, K.6
Hasumi, M.7
Toki, K.8
Ichimaru, N.9
Yazawa, K.10
Hanafusa, T.11
Namba, Y.12
Oka, K.13
Moriyama, T.14
Imai, E.15
Okuyama, A.16
Yamanaka, H.17
-
28
-
-
0031011137
-
Absence of deleterious effect on long-term kidney graft survival of rejection episodes with complete functional recovery
-
DOI 10.1097/00007890-199706270-00006
-
Vereerstraeten P, Abramowicz D, de Pauw L, Kinnaert P. Absence of deleterious effect on long-term kidney graft survival of rejection episodes with complete functional recovery. Transplantation 1997; 63:1739-1743. (Pubitemid 27278944)
-
(1997)
Transplantation
, vol.63
, Issue.12
, pp. 1739-1743
-
-
Vereerstraeten, P.1
Abramowicz, D.2
De Pauw, L.3
Kinnaert, P.4
-
29
-
-
0344553377
-
Heterologous immunity: An overlooked barrier to tolerance
-
DOI 10.1046/j.1600-065X.2003.00082.x
-
Adams AB, Pearson TC, Larsen CP. Heterologous immunity: an overlooked barrier to tolerance. Immunol Rev 2003; 196:147-160. (Pubitemid 37468109)
-
(2003)
Immunological Reviews
, vol.196
, pp. 147-160
-
-
Adams, A.B.1
Pearson, T.C.2
Larsen, C.P.3
-
31
-
-
65349189555
-
Costimulatory pathways in transplantation: Challenges and new developments
-
Li XC, Rothstein DM, Sayegh MH. Costimulatory pathways in transplantation: challenges and new developments. Immunol Rev 2009; 229:271-293.
-
(2009)
Immunol Rev
, vol.229
, pp. 271-293
-
-
Li, X.C.1
Rothstein, D.M.2
Sayegh, M.H.3
-
32
-
-
51849108540
-
The effect of costimulatory and interleukin 2 receptor blockade on regulatory T cells in renal transplantation
-
Bluestone JA, Liu W, Yabu JM, et al. The effect of costimulatory and interleukin 2 receptor blockade on regulatory T cells in renal transplantation. Am J Transplant 2008; 8:2086-2096.
-
(2008)
Am J Transplant
, vol.8
, pp. 2086-2096
-
-
Bluestone, J.A.1
Liu, W.2
Yabu, J.M.3
-
33
-
-
79953800720
-
Costimulatory blockade with mTOR inhibition abrogates effector T-cell responses allowing regulatory T-cell survival in renal transplantation
-
Bestard O, Cassis L, Cruzado JM, et al. Costimulatory blockade with mTOR inhibition abrogates effector T-cell responses allowing regulatory T-cell survival in renal transplantation. Transpl Int 2011; 24:451-460.
-
(2011)
Transpl Int
, vol.24
, pp. 451-460
-
-
Bestard, O.1
Cassis, L.2
Cruzado, J.M.3
-
34
-
-
78650818523
-
An integrated safety profile analysis of belatacept in kidney transplant recipients
-
Grinyo J, Charpentier B, Pestana JM, et al. An integrated safety profile analysis of belatacept in kidney transplant recipients. Transplantation 2010; 90:1521-1527.
-
(2010)
Transplantation
, vol.90
, pp. 1521-1527
-
-
Grinyo, J.1
Charpentier, B.2
Pestana, J.M.3
-
35
-
-
84889755254
-
-
Administration. UFaD [Accessed 30 August 2012]
-
Administration. UFaD. FDA labeling information-Nulojix. 2011. http://www.accessdata.fda.gov/drugsatfda-docs/label/2011/125288s0000lbl.pdf. [Accessed 30 August 2012].
-
(2011)
FDA Labeling Information-Nulojix
-
-
|