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Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 24, 2012, Pages 7351-7356

Synthesis and antiviral activity of novel HCV NS3 protease inhibitors with P4 capping groups

(22) Li, Xianfeng a Liu, Yang a Zhang, Yong Kang a Plattner, Jacob J a Baker, Stephen J a Bu, Wei a Liu, Liang a Zhou, Yasheen a Ding, Charles Z a Zhang, Suoming a Kazmierski, Wieslaw M b Hamatake, Robert b Duan, Maosheng b Wright, Lois L b Smith, Gary K b Jarvest, Richard L c Ji, Jing Jing b Cooper, Joel P b Tallant, Matthew D b Crosby, Renae M b more..

a PFIZER INC (United States)

b GLAXOSMITHKLINE (United States)

c GLAXOSMITHKLINE (United Kingdom)

Author keywords

Antiviral; HCV NS3; Hepatitis C virus; Protease inhibitor

Indexed keywords

ANTIVIRUS AGENT; NONSTRUCTURAL PROTEIN 3; NONSTRUCTURAL PROTEIN 3 INHIBITOR; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CELL ASSAY; CELL BASED REPLICON ASSAY; DRUG SYNTHESIS; ENZYME ASSAY; HEPATITIS C VIRUS; NONHUMAN;

AMIDES; ANIMALS; ANTIVIRAL AGENTS; CARBAMATES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE, VIRAL; GUANIDINES; HEPACIVIRUS; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; OXAMIC ACID; RATS; SERINE PROTEINASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP; UREA; VIRAL NONSTRUCTURAL PROTEINS;

HEPATITIS C VIRUS;

EID: 84870243131 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2012.10.075 Document Type: Article

Times cited : (7)

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