-
1
-
-
43449127502
-
Prostate cancer
-
Damber JE, Aus G 2008 Prostate cancer. Lancet 371:1710-1721
-
(2008)
Lancet
, vol.371
, pp. 1710-1721
-
-
Damber, J.E.1
Aus, G.2
-
2
-
-
4744347762
-
Mechanisms of androgen-refractory prostate cancer
-
Debes JD, Tindall DJ 2004 Mechanisms of androgen-refractory prostate cancer. N Engl J Med 351:1488-1490
-
(2004)
N Engl J Med
, vol.351
, pp. 1488-1490
-
-
Debes, J.D.1
Tindall, D.J.2
-
3
-
-
42749084744
-
Progress in understanding androgen-independent prostate cancer (AIPC): A review of potential endocrine-mediated mechanisms
-
Schröder FH 2008 Progress in understanding androgen-independent prostate cancer (AIPC): a review of potential endocrine-mediated mechanisms. Eur Urol 53:1129-1137
-
(2008)
Eur Urol
, vol.53
, pp. 1129-1137
-
-
Schröder, F.H.1
-
4
-
-
0842311632
-
The androgen axis in recurrent prostate cancer
-
Mohler JL, Gregory CW, Ford 3rd OH, Kim D, Weaver CM, Petrusz P, Wilson EM, French FS 2004 The androgen axis in recurrent prostate cancer. Clin Cancer Res 10:440-448
-
(2004)
Clin Cancer Res
, vol.10
, pp. 440-448
-
-
Mohler, J.L.1
Gregory, C.W.2
Ford III, O.H.3
Kim, D.4
Weaver, C.M.5
Petrusz, P.6
Wilson, E.M.7
French, F.S.8
-
5
-
-
27644452640
-
Testosterone and dihydrotestosterone tissue levels in recurrent prostate cancer
-
Titus MA, Schell MJ, Lih FB, Tomer KB, Mohler JL 2005 Testosterone and dihydrotestosterone tissue levels in recurrent prostate cancer. Clin Cancer Res 11:4653-4657
-
(2005)
Clin Cancer Res
, vol.11
, pp. 4653-4657
-
-
Titus, M.A.1
Schell, M.J.2
Lih, F.B.3
Tomer, K.B.4
Mohler, J.L.5
-
6
-
-
79957443342
-
Abiraterone and increased survival in metastatic prostate cancer
-
de Bono JS, Logothetis CJ, Molina A, Fizazi K, North S, Chu L, Chi KN, Jones RJ, Goodman Jr OB, Saad F, Staffurth JN, Mainwaring P, Harland S, Flaig TW, Hutson TE, Cheng T, Patterson H, Hainsworth JD, Ryan CJ, Sternberg CN, Ellard SL, Fléchon A, Saleh M, Scholz M, Efstathiou E, et al. 2011 Abiraterone and increased survival in metastatic prostate cancer. N Engl J Med 364:1995-2005
-
(2011)
N Engl J Med
, vol.364
, pp. 1995-2005
-
-
De Bono, J.S.1
Logothetis, C.J.2
Molina, A.3
Fizazi, K.4
North, S.5
Chu, L.6
Chi, K.N.7
Jones, R.J.8
Goodman Jr., O.B.9
Saad, F.10
Staffurth, J.N.11
Mainwaring, P.12
Harland, S.13
Flaig, T.W.14
Hutson, T.E.15
Cheng, T.16
Patterson, H.17
Hainsworth, J.D.18
Ryan, C.J.19
Sternberg, C.N.20
Ellard, S.L.21
Fléchon, A.22
Saleh, M.23
Scholz, M.24
Efstathiou, E.25
more..
-
7
-
-
84866770294
-
Increased survival with enzalutamide in prostate cancer after chemotherapy
-
the Affirm Investigators 10.1056/NEJMoa1207506
-
Scher HI, Fizazi K, Saad F, Taplin ME, Sternberg CN, Miller MD, de Wit R, Mulders P, Chi KN, Shore ND, Armstrong AJ, Flaig TW, Flechon A, Mainwaring P, Fleming M, Hainsworth JD, Hirmand M, Selby B, Seely L, de Bono JS; the Affirm Investigators 2012 Increased survival with enzalutamide in prostate cancer after chemotherapy. N Engl J Med 10.1056/NEJMoa1207506
-
(2012)
N Engl J Med
-
-
Scher, H.I.1
Fizazi, K.2
Saad, F.3
Taplin, M.E.4
Sternberg, C.N.5
Miller, M.D.6
De Wit, R.7
Mulders, P.8
Chi, K.N.9
Shore, N.D.10
Armstrong, A.J.11
Flaig, T.W.12
Flechon, A.13
Mainwaring, P.14
Fleming, M.15
Hainsworth, J.D.16
Hirmand, M.17
Selby, B.18
Seely, L.19
De Bono, J.S.20
more..
-
8
-
-
51049098138
-
Androgen levels increase by intratumoral de novo steroidogenesis during progression of castration-resistant prostate cancer
-
Locke JA, Guns ES, Lubik AA, Adomat HH, Hendy SC, Wood CA, Ettinger SL, Gleave ME, Nelson CC 2008 Androgen levels increase by intratumoral de novo steroidogenesis during progression of castration-resistant prostate cancer. Cancer Res 68:6407-6415
-
(2008)
Cancer Res
, vol.68
, pp. 6407-6415
-
-
Locke, J.A.1
Guns, E.S.2
Lubik, A.A.3
Adomat, H.H.4
Hendy, S.C.5
Wood, C.A.6
Ettinger, S.L.7
Gleave, M.E.8
Nelson, C.C.9
-
9
-
-
49249119358
-
Maintenance of intratumoral androgens in metastatic prostate cancer: A mechanism for castration-resistant tumor growth
-
Montgomery RB, Mostaghel EA, Vessella R, Hess DL, Kalhorn TF, Higano CS, True LD, Nelson PS 2008 Maintenance of intratumoral androgens in metastatic prostate cancer: a mechanism for castration-resistant tumor growth. Cancer Res 68:4447-4454
-
(2008)
Cancer Res
, vol.68
, pp. 4447-4454
-
-
Montgomery, R.B.1
Mostaghel, E.A.2
Vessella, R.3
Hess, D.L.4
Kalhorn, T.F.5
Higano, C.S.6
True, L.D.7
Nelson, P.S.8
-
10
-
-
33645056171
-
Increased expression of genes converting adrenal androgens to testosterone in androgen-independent prostate cancer
-
Stanbrough M, Bubley GJ, Ross K, Golub TR, Rubin MA, Penning TM, Febbo PG, Balk SP 2006 Increased expression of genes converting adrenal androgens to testosterone in androgen-independent prostate cancer. Cancer Res 66:2815-2825
-
(2006)
Cancer Res
, vol.66
, pp. 2815-2825
-
-
Stanbrough, M.1
Bubley, G.J.2
Ross, K.3
Golub, T.R.4
Rubin, M.A.5
Penning, T.M.6
Febbo, P.G.7
Balk, S.P.8
-
11
-
-
76249096762
-
Evidence of limited contributions for intratumoral steroidogenesis in prostate cancer
-
Hofland J, van Weerden WM, Dits NF, Steenbergen J, van Leenders GJ, Jenster G, Schröder FH, de Jong FH 2010 Evidence of limited contributions for intratumoral steroidogenesis in prostate cancer. Cancer Res 70:1256-1264
-
(2010)
Cancer Res
, vol.70
, pp. 1256-1264
-
-
Hofland, J.1
Van Weerden, W.M.2
Dits, N.F.3
Steenbergen, J.4
Van Leenders, G.J.5
Jenster, G.6
Schröder, F.H.7
De Jong, F.H.8
-
12
-
-
0023662289
-
The TGF-β family of growth and differentiation factors
-
Massagué J 1987 The TGF-β family of growth and differentiation factors. Cell 49:437-438
-
(1987)
Cell
, vol.49
, pp. 437-438
-
-
Massagué, J.1
-
14
-
-
0030920284
-
Inhibin interferes with activin signaling at the level of the activin receptor complex in Chinese hamster ovary cells
-
Martens JW, de Winter JP, Timmerman MA, McLuskey A, van Schaik RH, Themmen AP, de Jong FH 1997 Inhibin interferes with activin signaling at the level of the activin receptor complex in Chinese hamster ovary cells. Endocrinology 138:2928-2936
-
(1997)
Endocrinology
, vol.138
, pp. 2928-2936
-
-
Martens, J.W.1
De Winter, J.P.2
Timmerman, M.A.3
McLuskey, A.4
Van Schaik, R.H.5
Themmen, A.P.6
De Jong, F.H.7
-
15
-
-
0034704753
-
Betaglycan binds inhibin and can mediate functional antagonism of activin signalling
-
Lewis KA, Gray PC, Blount AL, MacConell LA, Wiater E, Bilezikjian LM, Vale W 2000 Betaglycan binds inhibin and can mediate functional antagonism of activin signalling. Nature 404:411-414
-
(2000)
Nature
, vol.404
, pp. 411-414
-
-
Lewis, K.A.1
Gray, P.C.2
Blount, A.L.3
MacConell, L.A.4
Wiater, E.5
Bilezikjian, L.M.6
Vale, W.7
-
16
-
-
0025117393
-
Activin-binding protein from rat ovary is follistatin
-
Nakamura T, Takio K, Eto Y, Shibai H, Titani K, Sugino H 1990 Activin-binding protein from rat ovary is follistatin. Science 247: 836-838
-
(1990)
Science
, vol.247
, pp. 836-838
-
-
Nakamura, T.1
Takio, K.2
Eto, Y.3
Shibai, H.4
Titani, K.5
Sugino, H.6
-
17
-
-
0036486076
-
Regulation of cell proliferation, apoptosis, and carcinogenesis by activin
-
Maywood
-
Chen YG, Lui HM, Lin SL, Lee JM, Ying SY 2002 Regulation of cell proliferation, apoptosis, and carcinogenesis by activin. Exp Biol Med (Maywood) 227:75-87
-
(2002)
Exp Biol Med
, vol.227
, pp. 75-87
-
-
Chen, Y.G.1
Lui, H.M.2
Lin, S.L.3
Lee, J.M.4
Ying, S.Y.5
-
18
-
-
0141842605
-
Expression of activin/inhibin signaling components in the human adrenal gland and the effects of activins and inhibins on adrenocortical steroidogenesis and apoptosis
-
Vänttinen T, Liu J, Kuulasmaa T, Kivinen P, Voutilainen R 2003 Expression of activin/inhibin signaling components in the human adrenal gland and the effects of activins and inhibins on adrenocortical steroidogenesis and apoptosis. J Endocrinol 178:479-489
-
(2003)
J Endocrinol
, vol.178
, pp. 479-489
-
-
Vänttinen, T.1
Liu, J.2
Kuulasmaa, T.3
Kivinen, P.4
Voutilainen, R.5
-
19
-
-
0025835902
-
Effect of recombinant activin on androgen synthesis in cultured human thecal cells
-
Hillier SG, Yong EL, Illingworth PJ, Baird DT, Schwall RH, Mason AJ 1991 Effect of recombinant activin on androgen synthesis in cultured human thecal cells. J Clin Endocrinol Metab 72:1206-1211
-
(1991)
J Clin Endocrinol Metab
, vol.72
, pp. 1206-1211
-
-
Hillier, S.G.1
Yong, E.L.2
Illingworth, P.J.3
Baird, D.T.4
Schwall, R.H.5
Mason, A.J.6
-
20
-
-
0025878644
-
Effect of activin A on dehydroepiandrosterone and testosterone secretion by primary immature porcine Leydig cells
-
Mauduit C, Chauvin MA, de Peretti E, Morera AM, Benahmed M 1991 Effect of activin A on dehydroepiandrosterone and testosterone secretion by primary immature porcine Leydig cells. Biol Reprod 45:101-109
-
(1991)
Biol Reprod
, vol.45
, pp. 101-109
-
-
Mauduit, C.1
Chauvin, M.A.2
De Peretti, E.3
Morera, A.M.4
Benahmed, M.5
-
21
-
-
84860715070
-
Inhibins and activins: Their roles in the adrenal gland and the development of adrenocortical tumors
-
Hofland J, de Jong FH 2012 Inhibins and activins: Their roles in the adrenal gland and the development of adrenocortical tumors. Mol Cell Endocrinol 359:92-100
-
(2012)
Mol Cell Endocrinol
, vol.359
, pp. 92-100
-
-
Hofland, J.1
De Jong, F.H.2
-
22
-
-
0033303686
-
Expression of activin A and follistatin core proteins by human prostate tumor cell lines
-
McPherson SJ, Mellor SL, Wang H, Evans LW, Groome NP, Risbridger GP 1999 Expression of activin A and follistatin core proteins by human prostate tumor cell lines. Endocrinology 140:5303-5309
-
(1999)
Endocrinology
, vol.140
, pp. 5303-5309
-
-
McPherson, S.J.1
Mellor, S.L.2
Wang, H.3
Evans, L.W.4
Groome, N.P.5
Risbridger, G.P.6
-
23
-
-
0033988581
-
Variations in activin receptor, inhibin/activin subunit and follistatin mRNAs in human prostate tumour tissues
-
van Schaik RH, Wierikx CD, Timmerman MA, Oomen MH, van Weerden WM, van der Kwast TH, van Steenbrugge GJ, de Jong FH 2000 Variations in activin receptor, inhibin/activin subunit and follistatin mRNAs in human prostate tumour tissues. Br J Cancer 82:112-117
-
(2000)
Br J Cancer
, vol.82
, pp. 112-117
-
-
Van Schaik, R.H.1
Wierikx, C.D.2
Timmerman, M.A.3
Oomen, M.H.4
Van Weerden, W.M.5
Van Der Kwast, T.H.6
Van Steenbrugge, G.J.7
De Jong, F.H.8
-
24
-
-
0031040843
-
Expression and localization of inhibin/activin subunits and activin receptors in the normal rat prostate
-
Ying SY, Zhang Z, Huang G 1997 Expression and localization of inhibin/activin subunits and activin receptors in the normal rat prostate. Life Sci 60:397-401
-
(1997)
Life Sci
, vol.60
, pp. 397-401
-
-
Ying, S.Y.1
Zhang, Z.2
Huang, G.3
-
25
-
-
0030833192
-
Growth inhibitory response to activin A and B by human prostate tumour cell lines, LNCaP and DU145
-
McPherson SJ, Thomas TZ, Wang H, Gurusinghe CJ, Risbridger GP 1997 Growth inhibitory response to activin A and B by human prostate tumour cell lines, LNCaP and DU145. J Endocrinol 154:535-545
-
(1997)
J Endocrinol
, vol.154
, pp. 535-545
-
-
McPherson, S.J.1
Thomas, T.Z.2
Wang, H.3
Gurusinghe, C.J.4
Risbridger, G.P.5
-
26
-
-
1542327547
-
Mutually antagonistic effects of androgen and activin in the regulation of prostate cancer cell growth
-
Carey JL, Sasur LM, Kawakubo H, Gupta V, Christian B, Bailey PM, Maheswaran S 2004 Mutually antagonistic effects of androgen and activin in the regulation of prostate cancer cell growth. Mol Endocrinol 18:696-707
-
(2004)
Mol Endocrinol
, vol.18
, pp. 696-707
-
-
Carey, J.L.1
Sasur, L.M.2
Kawakubo, H.3
Gupta, V.4
Christian, B.5
Bailey, P.M.6
Maheswaran, S.7
-
27
-
-
0031578249
-
Regulation of growth and prostatic marker expression by activin A in an androgen-sensitive prostate cancer cell line LNCAP
-
Zhang Z, Zhao Y, Batres Y, Lin MF, Ying SY 1997 Regulation of growth and prostatic marker expression by activin A in an androgen-sensitive prostate cancer cell line LNCAP. Biochem Biophys Res Commun 234:362-365
-
(1997)
Biochem Biophys Res Commun
, vol.234
, pp. 362-365
-
-
Zhang, Z.1
Zhao, Y.2
Batres, Y.3
Lin, M.F.4
Ying, S.Y.5
-
28
-
-
70349086989
-
Activin A enhances prostate cancer cell migration through activation of androgen receptor and is overexpressed in metastatic prostate cancer
-
Kang HY, Huang HY, Hsieh CY, Li CF, Shyr CR, Tsai MY, Chang C, Chuang YC, Huang KE 2009 Activin A enhances prostate cancer cell migration through activation of androgen receptor and is overexpressed in metastatic prostate cancer. J Bone Miner Res 24:1180-1193
-
(2009)
J Bone Miner Res
, vol.24
, pp. 1180-1193
-
-
Kang, H.Y.1
Huang, H.Y.2
Hsieh, C.Y.3
Li, C.F.4
Shyr, C.R.5
Tsai, M.Y.6
Chang, C.7
Chuang, Y.C.8
Huang, K.E.9
-
29
-
-
33847069683
-
The type III transforming growth factor-β receptor as a novel tumor suppressor gene in prostate cancer
-
Turley RS, Finger EC, Hempel N, How T, Fields TA, Blobe GC 2007 The type III transforming growth factor-β receptor as a novel tumor suppressor gene in prostate cancer. Cancer Res 67:1090-1098
-
(2007)
Cancer Res
, vol.67
, pp. 1090-1098
-
-
Turley, R.S.1
Finger, E.C.2
Hempel, N.3
How, T.4
Fields, T.A.5
Blobe, G.C.6
-
30
-
-
0031764969
-
Loss of the expression and localization of inhibin α-subunit in high grade prostate cancer
-
Mellor SL, Richards MG, Pedersen JS, Robertson DM, Risbridger GP 1998 Loss of the expression and localization of inhibin α-subunit in high grade prostate cancer. J Clin Endocrinol Metab 83:969-975
-
(1998)
J Clin Endocrinol Metab
, vol.83
, pp. 969-975
-
-
Mellor, S.L.1
Richards, M.G.2
Pedersen, J.S.3
Robertson, D.M.4
Risbridger, G.P.5
-
31
-
-
33748954261
-
Activin A circulating levels in patients with bone metastasis from breast or prostate cancer
-
Leto G, Incorvaia L, Badalamenti G, Tumminello FM, Gebbia N, Flandina C, Crescimanno M, Rini G 2006 Activin A circulating levels in patients with bone metastasis from breast or prostate cancer. Clin Exp Metastasis 23:117-122
-
(2006)
Clin Exp Metastasis
, vol.23
, pp. 117-122
-
-
Leto, G.1
Incorvaia, L.2
Badalamenti, G.3
Tumminello, F.M.4
Gebbia, N.5
Flandina, C.6
Crescimanno, M.7
Rini, G.8
-
32
-
-
0034784427
-
A novel gene on human chromosome 2p24 is differentially expressed between androgen-dependent and androgen-independent prostate cancer cells
-
Chang GT, Steenbeek M, Schippers E, Blok LJ, van Weerden WM, van Alewijk DC, Eussen BH, van Steenbrugge GJ, Brinkmann AO 2001 A novel gene on human chromosome 2p24 is differentially expressed between androgen-dependent and androgen-independent prostate cancer cells. Eur J Cancer 37:2129-2134
-
(2001)
Eur J Cancer
, vol.37
, pp. 2129-2134
-
-
Chang, G.T.1
Steenbeek, M.2
Schippers, E.3
Blok, L.J.4
Van Weerden, W.M.5
Van Alewijk, D.C.6
Eussen, B.H.7
Van Steenbrugge, G.J.8
Brinkmann, A.O.9
-
33
-
-
33846939508
-
Expression of activin and inhibin subunits, receptors and binding proteins in human pheochromocytomas: A study based on mRNA analysis and immunohistochemistry
-
Oxf
-
Hofland J, van Nederveen FH, Timmerman MA, Korpershoek E, de Herder WW, Lenders JW, Verhofstad AA, de Krijger RR, de Jong FH 2007 Expression of activin and inhibin subunits, receptors and binding proteins in human pheochromocytomas: a study based on mRNA analysis and immunohistochemistry. Clin Endocrinol (Oxf) 66:335-340
-
(2007)
Clin Endocrinol
, vol.66
, pp. 335-340
-
-
Hofland, J.1
Van Nederveen, F.H.2
Timmerman, M.A.3
Korpershoek, E.4
De Herder, W.W.5
Lenders, J.W.6
Verhofstad, A.A.7
De Krijger, R.R.8
De Jong, F.H.9
-
34
-
-
77951773289
-
Serum testosterone levels measured by isotope dilution-liquid chromatography-tandem mass spectrometry in postmenopausal women versus those in women who underwent bilateral oophorectomy
-
Bui HN, Struys EA, Martens F, de Ronde W, Thienpont LM, Kenemans P, Verhoeven MO, Jakobs C, Dijstelbloem HM, Blankenstein MA 2010 Serum testosterone levels measured by isotope dilution-liquid chromatography-tandem mass spectrometry in postmenopausal women versus those in women who underwent bilateral oophorectomy. Ann Clin Biochem 47:248-252
-
(2010)
Ann Clin Biochem
, vol.47
, pp. 248-252
-
-
Bui, H.N.1
Struys, E.A.2
Martens, F.3
De Ronde, W.4
Thienpont, L.M.5
Kenemans, P.6
Verhoeven, M.O.7
Jakobs, C.8
Dijstelbloem, H.M.9
Blankenstein, M.A.10
-
35
-
-
0030726297
-
Expression and localization of activin subunits and follistatins in tissues from men with high grade prostate cancer
-
Thomas TZ, Wang H, Niclasen P, O'Bryan MK, Evans LW, Groome NP, Pedersen J, Risbridger GP 1997 Expression and localization of activin subunits and follistatins in tissues from men with high grade prostate cancer. J Clin Endocrinol Metab 82:3851-3858
-
(1997)
J Clin Endocrinol Metab
, vol.82
, pp. 3851-3858
-
-
Thomas, T.Z.1
Wang, H.2
Niclasen, P.3
O'Bryan, M.K.4
Evans, L.W.5
Groome, N.P.6
Pedersen, J.7
Risbridger, G.P.8
-
36
-
-
7444233759
-
The backdoor pathway to dihydrotestosterone
-
Auchus RJ 2004 The backdoor pathway to dihydrotestosterone. Trends Endocrinol Metab 15:432-438
-
(2004)
Trends Endocrinol Metab
, vol.15
, pp. 432-438
-
-
Auchus, R.J.1
-
38
-
-
0028944970
-
Regulation of proliferation and production of prostate-specific antigen in androgen-sensitive prostatic cancer cells, LNCaP, by dihydrotestosterone
-
Lee C, Sutkowski DM, Sensibar JA, Zelner D, Kim I, Amsel I, Shaw N, Prins GS, Kozlowski JM 1995 Regulation of proliferation and production of prostate-specific antigen in androgen-sensitive prostatic cancer cells, LNCaP, by dihydrotestosterone. Endocrinology 136:796-803
-
(1995)
Endocrinology
, vol.136
, pp. 796-803
-
-
Lee, C.1
Sutkowski, D.M.2
Sensibar, J.A.3
Zelner, D.4
Kim, I.5
Amsel, I.6
Shaw, N.7
Prins, G.S.8
Kozlowski, J.M.9
-
39
-
-
68949094223
-
Selective inhibition of CYP17 with abiraterone acetate is highly active in the treatment of castration-resistant prostate cancer
-
Attard G, Reid AH, A'Hern R, Parker C, Oommen NB, Folkerd E, Messiou C, Molife LR, Maier G, Thompson E, Olmos D, Sinha R, Lee G, Dowsett M, Kaye SB, Dearnaley D, Kheoh T, Molina A, de Bono JS 2009 Selective inhibition of CYP17 with abiraterone acetate is highly active in the treatment of castration-resistant prostate cancer. J Clin Oncol 27:3742-3748
-
(2009)
J Clin Oncol
, vol.27
, pp. 3742-3748
-
-
Attard, G.1
Reid, A.H.2
A'Hern, R.3
Parker, C.4
Oommen, N.B.5
Folkerd, E.6
Messiou, C.7
Molife, L.R.8
Maier, G.9
Thompson, E.10
Olmos, D.11
Sinha, R.12
Lee, G.13
Dowsett, M.14
Kaye, S.B.15
Dearnaley, D.16
Kheoh, T.17
Molina, A.18
De Bono, J.S.19
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