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Volumn 95, Issue 11, 2012, Pages 2296-2303
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Asymmetric proline-catalyzed addition of aldehydes to 3H-indol-3-ones: Enantioselective synthesis of 2,3-dihydro-1H-indol-3-ones with quaternary stereogenic centers
a
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Author keywords
Catalysis; Hinckdentine A; Indol 2 acetaldehyde; Mannich reaction; Proline
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Indexed keywords
ALIPHATIC ALDEHYDES;
CHIRAL DERIVATIVES;
ENANTIOSELECTIVE SYNTHESIS;
HINCKDENTINE A;
INDOL-2-ACETALDEHYDE;
MANNICH REACTIONS;
NATURAL PRODUCTS;
PROLINE;
STEREOGENIC CENTERS;
ALDEHYDES;
AMINO ACIDS;
CATALYSIS;
ORGANIC COMPOUNDS;
ENANTIOSELECTIVITY;
2 (2 BROMOPHENYL) 2 (2 HYDROXYETHYL) 2,3 DIHYDRO 1H INDOL 3 ONE;
2 (2 BROMOPHENYL) 2,3 DIHYDRO 2 (2 HYDROXYETHYL) 1H INDOL 3 ONE;
2 (2 HYDROXYETHYL) 2 (4 METHOXYPHENYL) 2,3 DIHYDRO 1H INDOL 3 ONE;
2 (2 HYDROXYETHYL) 2 (4 METHYLPHENYL) 2,3 DIHYDRO 1H INDOL 3 ONE;
2 (2 HYDROXYETHYL) 2 (NAPHTHALEN 2 YL) 2,3 DIHYDRO 1H INDOL 3 ONE;
2 (2 HYDROXYETHYL) 2 PHENYL 2,3 DIHYDRO 1H INDOL3 ONE;
2 (4 BROMOPHENYL) 2 (2 HYDROXYETHYL) 2,3 DIHYDRO 1H INDOL 3 ONE;
2 (4 CHLOROPHENYL) 2 (2 HYDROXYETHYL) 2,3 DIHYDRO 1H INDOL 3 ONE;
2 (4 ETHYLPHENYL) 2 (2 HYDROXYETHYL) 1,2 DIHYDRO 3H INDOL 3 ONE;
2 (4 FLUOROPHENYL) 2 (2 HYDROXYETHYL) 2,3 DIHYDRO 1H INDOL 3 ONE;
2 [1 (HYDROXYMETHYL) 2 METHYLPROPYL] 2 (4 METHYLPHENYL) 2,3 DIHYDRO 1H INDOL 3 ONE;
2 [1 (HYDROXYMETHYL)BUTYL] 2 (4 METHYLPHENYL) 2,3 DIHYDRO 1H INDOL 3 ONE;
ALDEHYDE DERIVATIVE;
ALIPHATIC COMPOUND;
ANTIINFLAMMATORY AGENT;
ANTINEOPLASTIC AGENT;
HINCKDENTINE;
INDOLE DERIVATIVE;
NATURAL PRODUCT;
PROLINE;
UNCLASSIFIED DRUG;
ADDITION REACTION;
ARTICLE;
ASYMMETRIC SYNTHESIS;
CHIRALITY;
CONTROLLED STUDY;
ENANTIOSELECTIVITY;
PRIORITY JOURNAL;
STEREOSPECIFICITY;
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EID: 84870231889
PISSN: 0018019X
EISSN: 15222675
Source Type: Journal
DOI: 10.1002/hlca.201200498 Document Type: Article |
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Times cited : (53)
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References (47)
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