Generation of retinal cells from pluripotent stem cells

Progress in Brain Research

Volumn 201, Issue , 2012, Pages 171-181

  Jin, Zi Bing ^a   Takahashi, Masayo ^b,c  

^a WENZHOU MEDICAL UNIVERSITY   (China)

^b RIKEN Center for Biosystems Dynamics Research   (Japan)

^c KYOTO UNIVERSITY   (Japan)

Author keywords

Differentiation; Photoreceptor; Pluripotent stem cell; Retina; RPE

Indexed keywords

APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL FUNCTION; CELL LINE; CELL MATURATION; EMBRYO DEVELOPMENT; EMBRYONIC STEM CELL; HUMAN; NONHUMAN; PHOTORECEPTOR CELL; PIGMENT EPITHELIUM; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; RETINA BIPOLAR GANGLION CELL; RETINA CELL; RETINA DEGENERATION; RETINA DEVELOPMENT; RETINA GANGLION CELL; RETINA MACULA AGE RELATED DEGENERATION; RETINA NERVE CELL; STARGARDT DISEASE; STEM CELL; STEM CELL TRANSPLANTATION;

EID: 84870231673     PISSN: 00796123     EISSN: 18757855     Source Type: Book Series    
DOI: 10.1016/B978-0-444-59544-7.00008-1     Document Type: Chapter

References (38)

1. Cavodeassi F., Carreira-Barbosa F., Young R.M., Concha M.L., Allende M.L., Houart C., Tada M., Wilson S.W. Early stages of zebrafish eye formation require the coordinated activity of Wnt11, Fz5, and the Wnt/beta-catenin pathway. Neuron 2005, 47:43-56.
2. Chen M., Chen Q., Sun X., Shen W., Liu B., Zhong X., Leng Y., Li C., Zhang W., Chai F., Huang B., Gao Q., Xiang A.P., Zhuo Y., Ge J. Generation of retinal ganglion-like cells from reprogrammed mouse fibroblasts. Invest. Ophthalmol. Vis. Sci. 2010, 51:5970-5978.
3. Chow R.L., Altmann C.R., Lang R.A., Hemmati-Brivanlou A. Pax6 induces ectopic eyes in a vertebrate. Development 1999, 126:4213-4222.
4. Eiraku M., Takata N., Ishibashi H., Kawada M., Sakakura E., Okuda S., Sekiguchi K., Adachi T., Sasai Y. Self-organizing optic-cup morphogenesis in three-dimensional culture. Nature 2011, 472:51-56.
5. Evans M.J., Kaufman M.H. Establishment in culture of pluripotential cells from mouse embryos. Nature 1981, 292:154-156.
6. Furukawa T., Kozak C.A., Cepko C.L. Rax, a novel paired-type homeobox gene, shows expression in the anterior neural fold and developing retina. Proc. Natl. Acad. Sci. U.S.A. 1997, 94:3088-3093.
7. Haruta M., Sasai Y., Kawasaki H., Amemiya K., Ooto S., Kitada M., Suemori H., Nakatsuji N., Ide C., Honda Y., Takahashi M. In vitro and in vivo characterization of pigment epithelial cells differentiated from primate embryonic stem cells. Invest. Ophthalmol. Vis. Sci. 2004, 45:1020-1025.
8. Hennig A.K., Peng G.H., Chen S. Regulation of photoreceptor gene expression by Crx-associated transcription factor network. Brain Res. 2008, 1192:114-133.
9. Hirami Y., Osakada F., Takahashi K., Okita K., Yamanaka S., Ikeda H., Yoshimura N., Takahashi M. Generation of retinal cells from mouse and human induced pluripotent stem cells. Neurosci. Lett. 2009, 458:126-131.
10. Hyatt G.A., Schmitt E.A., Fadool J.M., Dowling J.E. Retinoic acid alters photoreceptor development in vivo. Proc. Natl. Acad. Sci. U.S.A. 1996, 93:13298-13303.
11. Ikeda H., Osakada F., Watanabe K., Mizuseki K., Haraguchi T., Miyoshi H., Kamiya D., Honda Y., Sasai N., Yoshimura N., Takahashi M., Sasai Y. Generation of Rx+/Pax6+ neural retinal precursors from embryonic stem cells. Proc. Natl. Acad. Sci. U.S.A. 2005, 102:11331-11336.
12. Jagatha B., Divya M.S., Sanalkumar R., Indulekha C.L., Vidyanand S., Divya T.S., Das A.V., James J. In vitro differentiation of retinal ganglion-like cells from embryonic stem cell derived neural progenitors. Biochem. Biophys. Res. Commun. 2009, 380:230-235.
13. Jin Z.B., Okamoto S., Mandai M., Takahashi M. Induced pluripotent stem cells for retinal degenerative diseases: a new perspective on the challenges. J. Genet. 2009, 88:417-424.
14. Jin Z.B., Okamoto S., Osakada F., Homma K., Assawachananont J., Hirami Y., Iwata T., Takahashi M. Modeling retinal degeneration using patient-specific induced pluripotent stem cells. PLoS One 2011, 6:e17084.
15. Jin Z.B., Okamoto S., Xiang P., Takahashi M. Integration-free iPS cells derived from retinitis pigmentosa patient for disease modeling. Stem Cells Trans. Med. 2012, 1:503-509.
16. Juuti-Uusitalo K., Vaajasaari H., Ryhanen T., Narkilahti S., Suuronen R., Mannermaa E., Kaarniranta K., Skottman H. Efflux protein expression in human stem cell-derived retinal pigment epithelial cells. PLoS One 2012, 7:e30089.
17. Kawasaki H., Suemori H., Mizuseki K., Watanabe K., Urano F., Ichinose H., Haruta M., Takahashi M., Yoshikawa K., Nishikawa S., Nakatsuji N., Sasai Y. Generation of dopaminergic neurons and pigmented epithelia from primate ES cells by stromal cell-derived inducing activity. Proc. Natl. Acad. Sci. U.S.A. 2002, 99:1580-1585.
18. Klimanskaya I., Hipp J., Rezai K.A., West M., Atala A., Lanza R. Derivation and comparative assessment of retinal pigment epithelium from human embryonic stem cells using transcriptomics. Cloning Stem Cells 2004, 6:217-245.
19. Lagutin O.V., Zhu C.C., Kobayashi D., Topczewski J., Shimamura K., Puelles L., Russell H.R., McKinnon P.J., Solnica-Krezel L., Oliver G. Six3 repression of Wnt signaling in the anterior neuroectoderm is essential for vertebrate forebrain development. Genes Dev. 2003, 17:368-379.
20. Lamba D.A., Karl M.O., Ware C.B., Reh T.A. Efficient generation of retinal progenitor cells from human embryonic stem cells. Proc. Natl. Acad. Sci. U.S.A. 2006, 103:12769-12774.
21. Li W., Sun W., Zhang Y., Wei W., Ambasudhan R., Xia P., Talantova M., Lin T., Kim J., Wang X., Kim W.R., Lipton S.A., Zhang K., Ding S. Rapid induction and long-term self-renewal of primitive neural precursors from human embryonic stem cells by small molecule inhibitors. Proc. Natl. Acad. Sci. U.S.A. 2011, 108:8299-8304.
22. MacLaren R.E., Pearson R.A., MacNeil A., Douglas R.H., Salt T.E., Akimoto M., Swaroop A., Sowden J.C., Ali R.R. Retinal repair by transplantation of photoreceptor precursors. Nature 2006, 444:203-207.
23. Mathers P.H., Grinberg A., Mahon K.A., Jamrich M. The Rx homeobox gene is essential for vertebrate eye development. Nature 1997, 387:603-607.
24. McUsic A.C., Lamba D.A., Reh T.A. Guiding the morphogenesis of dissociated newborn mouse retinal cells and hES cell-derived retinal cells by soft lithography-patterned microchannel PLGA scaffolds. Biomaterials 2012, 33:1396-1405.
25. Meyer J.S., Howden S.E., Wallace K.A., Verhoeven A.D., Wright L.S., Capowski E.E., Pinilla I., Martin J.M., Tian S., Stewart R., Pattnaik B., Thomson J.A., Gamm D.M. Optic vesicle-like structures derived from human pluripotent stem cells facilitate a customized approach to retinal disease treatment. Stem Cells 2011, 29:1206-1218.
26. Mukhopadhyay M., Shtrom S., Rodriguez-Esteban C., Chen L., Tsukui T., Gomer L., Dorward D.W., Glinka A., Grinberg A., Huang S.P., Niehrs C., Izpisua Belmonte J.C., Westphal H. Dickkopf1 is required for embryonic head induction and limb morphogenesis in the mouse. Dev. Cell 2001, 1:423-434.
27. Okamoto S., Takahashi M. Induction of retinal pigment epithelial cells from monkey iPS cells. Invest. Ophthalmol. Vis. Sci. 2011, 52:8785-8790.
28. Osakada F., Ikeda H., Mandai M., Wataya T., Watanabe K., Yoshimura N., Akaike A., Sasai Y., Takahashi M. Toward the generation of rod and cone photoreceptors from mouse, monkey and human embryonic stem cells. Nat. Biotechnol. 2008, 26:215-224.
29. Osakada F., Jin Z.B., Hirami Y., Ikeda H., Danjyo T., Watanabe K., Sasai Y., Takahashi M. In vitro differentiation of retinal cells from human pluripotent stem cells by small-molecule induction. J. Cell Sci. 2009, 122:3169-3179.
30. Pearson R.A., Barber A.C., Rizzi M., Hippert C., Xue T., West E.L., Duran Y., Smith A.J., Chuang J.Z., Azam S.A., Luhmann U.F., Benucci A., Sung C.H., Bainbridge J.W., Carandini M., Yau K.W., Sowden J.C., Ali R.R. Restoration of vision after transplantation of photoreceptors. Nature 2012, 485:99-103.
31. Pizzarello L., Abiose A., Ffytche T., Duerksen R., Thulasiraj R., Taylor H., Faal H., Rao G., Kocur I., Resnikoff S. VISION 2020: The Right to Sight: a global initiative to eliminate avoidable blindness. Arch. Ophthalmol. 2004, 122:615-620.
32. Schwartz S.D., Hubschman J.P., Heilwell G., Franco-Cardenas V., Pan C.K., Ostrick R.M., Mickunas E., Gay R., Klimanskaya I., Lanza R. Embryonic stem cell trials for macular degeneration: a preliminary report. Lancet 2012, 379:713-720.
33. Suga H., Kadoshima T., Minaguchi M., Ohgushi M., Soen M., Nakano T., Takata N., Wataya T., Muguruma K., Miyoshi H., Yonemura S., Oiso Y., Sasai Y. Self-formation of functional adenohypophysis in three-dimensional culture. Nature 2011, 480:57-62.
34. Swaroop A., Kim D., Forrest D. Transcriptional regulation of photoreceptor development and homeostasis in the mammalian retina. Nat. Rev. Neurosci. 2010, 11:563-576.
35. Takahashi K., Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006, 126:663-676.
36. Tezel T.H., Del Priore L.V., Berger A.S., Kaplan H.J. Adult retinal pigment epithelial transplantation in exudative age-related macular degeneration. Am. J. Ophthalmol. 2007, 143:584-595.
37. Zhu D., Deng X., Spee C., Sonoda S., Hsieh C.L., Barron E., Pera M., Hinton D.R. Polarized secretion of PEDF from human embryonic stem cell-derived RPE promotes retinal progenitor cell survival. Invest. Ophthalmol. Vis. Sci. 2011, 52:1573-1585.
38. Zuber M.E., Gestri G., Viczian A.S., Barsacchi G., Harris W.A. Specification of the vertebrate eye by a network of eye field transcription factors. Development 2003, 130:5155-5167.