CoMFA and CoMSIA studies on aryl carboxylic acid amide derivatives as dihydroorotate dehydrogenase (DHODH) inhibitors vivek k. vyas

Current Computer-Aided Drug Design

Volumn 8, Issue 4, 2012, Pages 271-282

  Vyas, Vivek K ^a   Ghate, Manjunath ^a  

^a NIRMA UNIVERSITY   (India)

Author keywords

3D QSAR; Aryl carboxylic acid amide derivatives; CoMFA; COMSIA; HDHODH inhibitors

Indexed keywords

CARBOXYLIC ACIDS; DISEASES;

3D-QSAR; ARYL CARBOXYLIC ACID AMIDE DERIVATIVE; ARYL CARBOXYLIC ACIDS; COMPARATIVE MOLECULAR FIELD ANALYSIS; COMSIA; FLAVOENZYMES; HDHODH INHIBITOR; INDEX MODELS; MOLECULAR SIMILARITY; SIMILARITY INDICES;

AMIDES;

DIHYDROOROTATE DEHYDROGENASE INHIBITOR;

ARTICLE; BOOTSTRAPPING; CHEMICAL REACTION; COMPARATIVE MOLECULAR FIELD ANALYSIS; COMPARATIVE MOLECULAR SIMILARITY INDICES ANALYSIS; DRUG CONFORMATION; DRUG DESIGN; DRUG STRUCTURE; HYDROGEN BOND; HYDROPHOBICITY; IC 50; INTERFEROMETRY; LIPOPHILICITY; PARTIAL LEAST SQUARES REGRESSION; PREDICTIVE VALUE; QUANTITATIVE STRUCTURE ACTIVITY RELATION; STATIC ELECTRICITY; STEREOSPECIFICITY;

EID: 84870210536     PISSN: 15734099     EISSN: 18756697     Source Type: Journal    
DOI: 10.2174/157340912803519598     Document Type: Article

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