-
2
-
-
33744547840
-
Pharmacogenetics and pharmacogenomics: origin, status, and the hope for personalized medicine.
-
10.1038/sj.tpj.6500361, 16415920
-
Kalow W. Pharmacogenetics and pharmacogenomics: origin, status, and the hope for personalized medicine. Pharmacogenomics J 2006, 6:162-165. 10.1038/sj.tpj.6500361, 16415920.
-
(2006)
Pharmacogenomics J
, vol.6
, pp. 162-165
-
-
Kalow, W.1
-
3
-
-
84868243529
-
CFTR potentiator VX-770 (ivacaftor) opens the defective channel gate of mutant CFTR in a phosphorylation-dependent but ATP-independent manner
-
10.1074/jbc.M112.393637, 22942289
-
Eckford PD, Li C, Ramjeesingh M, Bear CE. CFTR potentiator VX-770 (ivacaftor) opens the defective channel gate of mutant CFTR in a phosphorylation-dependent but ATP-independent manner. J Biol Chem 2012, 287:36639-36649. 10.1074/jbc.M112.393637, 22942289.
-
(2012)
J Biol Chem
, vol.287
, pp. 36639-36649
-
-
Eckford, P.D.1
Li, C.2
Ramjeesingh, M.3
Bear, C.E.4
-
4
-
-
84858433310
-
Personal omics profiling reveals dynamic molecular and medical phenotypes
-
10.1016/j.cell.2012.02.009, 22424236
-
Chen R, Mias GI, Li-Pook-Than J, Jiang L, Lam HY, Chen R, Miriami E, Karczewski KJ, Hariharan M, Dewey FE, Cheng Y, Clark MJ, Im H, Habegger L, Balasubramanian S, O'Huallachain M, Dudley JT, Hillenmeyer S, Haraksingh R, Sharon D, Euskirchen G, Lacroute P, Bettinger K, Boyle AP, Kasowski M, Grubert F, Seki S, Garcia M, Whirl-Carrillo M, Gallardo M, et al. Personal omics profiling reveals dynamic molecular and medical phenotypes. Cell 2012, 148:1293-1307. 10.1016/j.cell.2012.02.009, 22424236.
-
(2012)
Cell
, vol.148
, pp. 1293-1307
-
-
Chen, R.1
Mias, G.I.2
Li-Pook-Than, J.3
Jiang, L.4
Lam, H.Y.5
Chen, R.6
Miriami, E.7
Karczewski, K.J.8
Hariharan, M.9
Dewey, F.E.10
Cheng, Y.11
Clark, M.J.12
Im, H.13
Habegger, L.14
Balasubramanian, S.15
O'Huallachain, M.16
Dudley, J.T.17
Hillenmeyer, S.18
Haraksingh, R.19
Sharon, D.20
Euskirchen, G.21
Lacroute, P.22
Bettinger, K.23
Boyle, A.P.24
Kasowski, M.25
Grubert, F.26
Seki, S.27
Garcia, M.28
Whirl-Carrillo, M.29
Gallardo, M.30
more..
-
5
-
-
84871344105
-
Quantitative and Systems Pharmacology in the Post-genomic Era: New Approaches to Discovering Drugs and Understanding Therapeutic Mechanisms
-
(Ed)
-
Ward R, . (Ed) Quantitative and Systems Pharmacology in the Post-genomic Era: New Approaches to Discovering Drugs and Understanding Therapeutic Mechanisms. (Ed)., http://www.nigms.nih.gov/nr/rdonlyres/8ecb1f7c-be3b-431f-89e6-a43411811ab1/0/systemspharmawpsorger2011.pdf
-
-
-
Ward, R.1
-
6
-
-
84871357552
-
Tamoxifen use in postmenopausal breast cancer: CYP2D6 matters.
-
Brauch H, Schroth W, Goetz MP, Mürdter TE, Winter S, Ingle JN, Schwab M, Eichelbaum M. Tamoxifen use in postmenopausal breast cancer: CYP2D6 matters. J Clin Oncol 2012,
-
(2012)
J Clin Oncol
-
-
Brauch, H.1
Schroth, W.2
Goetz, M.P.3
Mürdter, T.E.4
Winter, S.5
Ingle, J.N.6
Schwab, M.7
Eichelbaum, M.8
-
7
-
-
80052962391
-
Clinical Pharmacogenetics Implementation Consortium Guidelines for CYP2C9 and VKORC1 genotypes and warfarin dosing.
-
10.1038/clpt.2011.185, 3187550,3187550, 21900891, Clinical Pharmacogenetics Implementation Consortium
-
Johnson JA, Gong L, Whirl-Carrillo M, Gage BF, Scott SA, Stein CM, Anderson JL, Kimmel SE, Lee MT, Pirmohamed M, Wadelius M, Klein TE, Altman RB, . Clinical Pharmacogenetics Implementation Consortium Clinical Pharmacogenetics Implementation Consortium Guidelines for CYP2C9 and VKORC1 genotypes and warfarin dosing. Clin Pharmacol Ther 2011, 90:625-629. 10.1038/clpt.2011.185, 3187550,3187550, 21900891, Clinical Pharmacogenetics Implementation Consortium.
-
(2011)
Clin Pharmacol Ther
, vol.90
, pp. 625-629
-
-
Johnson, J.A.1
Gong, L.2
Whirl-Carrillo, M.3
Gage, B.F.4
Scott, S.A.5
Stein, C.M.6
Anderson, J.L.7
Kimmel, S.E.8
Lee, M.T.9
Pirmohamed, M.10
Wadelius, M.11
Klein, T.E.12
Altman, R.B.13
-
8
-
-
80052954066
-
Warfarin pharmacogenetics meets clinical use.
-
Schwab M, Schaeffeler E. Warfarin pharmacogenetics meets clinical use. Blood 2011, 18:2938-2939.
-
(2011)
Blood
, vol.18
, pp. 2938-2939
-
-
Schwab, M.1
Schaeffeler, E.2
-
9
-
-
84871351017
-
WarfarinDosing.
-
WarfarinDosing. , http://www.warfarindosing.org
-
-
-
-
10
-
-
79951811383
-
The emerging role of electronic medical records in pharmacogenomics.
-
10.1038/clpt.2010.260, 3204342, 21248726
-
Wilke RA, Xu H, Denny JC, Roden DM, Krauss RM, McCarty CA, Davis RL, Skaar T, Lamba J, Savova G. The emerging role of electronic medical records in pharmacogenomics. Clin Pharmacol Ther 2011, 89:379-386. 10.1038/clpt.2010.260, 3204342, 21248726.
-
(2011)
Clin Pharmacol Ther
, vol.89
, pp. 379-386
-
-
Wilke, R.A.1
Xu, H.2
Denny, J.C.3
Roden, D.M.4
Krauss, R.M.5
McCarty, C.A.6
Davis, R.L.7
Skaar, T.8
Lamba, J.9
Savova, G.10
-
11
-
-
84862200972
-
Escaping the EHR trap--the future of health IT.
-
10.1056/NEJMp1203102, 22693995
-
Mandl KD, Kohane IS. Escaping the EHR trap--the future of health IT. N Engl J Med 2012, 366:2240-2242. 10.1056/NEJMp1203102, 22693995.
-
(2012)
N Engl J Med
, vol.366
, pp. 2240-2242
-
-
Mandl, K.D.1
Kohane, I.S.2
|