Otx2 selectively controls the neurogenesis of specific neuronal subtypes of the ventral tegmental area and compensates En1-dependent neuronal loss and MPTP vulnerability

Developmental Biology

Volumn 373, Issue 1, 2013, Pages 176-183

  Di Giovannantonio, Luca Giovanni ^a   Di Salvio, Michela ^a   Acampora, Dario ^a,b   Prakash, Nilima ^c   Wurst, Wolfgang ^c,d,e   Simeone, Antonio ^a,b  

^a CEINGE BIOTECNOLOGIE AVANZATE   (Italy)

^b INSTITUTE OF GENETICS AND BIOPHYSICS ADRIANO BUZZATI TRAVERSO   (Italy)

^c TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^d MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

^e GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

Author keywords

Dopaminergic progenitors; En1; Neuronal identity; Otx2; Substantia nigra; Ventral tegmental area

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; ALDEHYDE DEHYDROGENASE ISOENZYME 2; BRAIN PROTEIN; CALBINDIN; DOPAMINE TRANSPORTER; EN1 PROTEIN; G PROTEIN COUPLED INWARDLY RECTIFYING POTASSIUM CHANNEL; TRANSCRIPTION FACTOR OTX2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL LOSS; CELL SPECIFICITY; CELL TYPE; DIENCEPHALON; DOPAMINERGIC NERVE CELL; DRUG SENSITIVITY; EMBRYO; FEMALE; HAPLOINSUFFICIENCY; MESENCEPHALON; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN GLYCOSYLATION; SUBSTANTIA NIGRA PARS COMPACTA; VENTRAL TEGMENTUM;

EID: 84870054767     PISSN: 00121606     EISSN: 1095564X     Source Type: Journal    
DOI: 10.1016/j.ydbio.2012.10.022     Document Type: Article

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