A facile diversity-oriented synthesis of imidazo[1,2-a]pyrazinones via gold-catalyzed regioselective heteroannulation of propynylaminopyrazinones

Tetrahedron

Volumn 69, Issue 1, 2013, Pages 359-365

  Vachhani, Dipak D ^a   Modha, Sachin G ^a   Sharma, Abhishek ^a   Van Der Eycken, Erik V ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Alkyne; Gold; Heteroannulation; Imidazopyrazinone; Suzuki

Indexed keywords

3 (1H INDOL 5 YL)METHYLENE) 7 BENZYL 5 CHLORO 2,3 DIHYDROIMIDAZO[1,2 A]PYRAZIN 8(7H) ONE; 3 (3 (1H INDOL 5 YL)PROP 2 YNYLAMINO) 1 BENZYL 5 CHLOROPYRAZIN 2(1H) ONE; 3 BENZYLIDENE 5 CHLORO 6,7 BIS(4 METHOXYPHENYL) 2,3 DIHYDROIMIDAZO[1,2 A]PYRAZIN 8(7H) ONE; 5 (3 CHLOROPHENYL) 3,7 DIMETHYL 6 PHENYLIMIDAZO[1,2 A]PYRAZIN 8(7H) ONE; 5 CHLORO 1 (4 METHOXYBENZYL) 3 (PROP 2 YNYLAMINO)PYRAZIN 2(1H) ONE; 5 CHLORO 1 (4 METHOXYPHENYL) 3 (PROP 2 YNYLAMINO)PYRAZIN 2(1H) ONE; 5 CHLORO 1 METHYL 3 (3 (NAPHTHALEN 1 YL)PROP 2 YNYLAMINO) 6 PHENYLPYRAZIN 2 (1H) ONE; 5 CHLORO 1,6 BIS(4 METHOXYPHENYL) 3 (3 O TOLYLPROP 2 YNYLAMINO)PYRAZIN 2(1H) ONE; 5 CHLORO 1,6 BIS(4 METHOXYPHENYL) 3 (3 PHENYLPROP 2 YNYLAMINO)PYRAZIN 2(1H) ONE; 5 CHLORO 3 (2 CHLOROPYRIDIN 4 YL)METHYLENE) 7 (4 METHOXYBENZYL) 2,3 DIHYDROIMIDAZO[1,2 A]PYRAZIN 8(7H) ONE; 5 CHLORO 3 (3 (2 CHLOROPYRIDIN 4 YL)PROP 2 YNYLAMINO) 1 (4 METHOXYBENZYL)PYRAZIN 2(1H) ONE; 5 CHLORO 3 METHYL 7 (3 PHENYLPROPYL) IMIDAZO[1,2 A]PYRAZIN 8 (7H) ONE; 5 CHLORO 3,7 DIMETHYL 6 PHENYLIMIDAZO[1,2 A]PYRAZIN 8(7H) ONE; 5 CHLORO 6 ISOBUTYL 7 (4 METHOXYBENZYL) 3 METHYLIMIDAZO[1,2 A]PYRAZINE 8(7H) ONE; 5 CHLORO 6,7 BIS(4 METHOXYPHENYL) 3 (2 METHYLBENZYLIDENE) 2,3 DIHYDROIMIDAZO[1,2 A]PYRAZIN 8(7H) ONE; 5 CHLORO 7 (4 METHOXYBENZYL) 3,6 DIMETHYLIMIDAZO[1,2 A]PYRAZIN 8(7H) ONE; 5 CHLORO 7 (4 METHOXYBENZYL) 6 (4 METHOXYPHENYL) 3 METHYLIMIDAZO[1,2 A]PYRAZIN 8(7H) ONE; 7 (4 METHOXYBENZYL) 3 METHYL 5 (THIOPHEN 3 YL)IMIDAZO[1,2 A]PYRAZIN 8(7H) ONE; 7 (4 METHOXYPHENYL) 3 METHYL 5 4 TOLYLIMIDAZO[1,2 A]PYRAZIN 8(7H) ONE; 7 (4 METHOXYPHENYL) 3 METHYL 5 PHENYLIMIDAZO[1,2 A]PYRAZIN 8(7H) ONE; AMINE; BORONIC ACID DERIVATIVE; GOLD; PYRAZINE DERIVATIVE; SOLVENT; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; DRUG SYNTHESIS; MICROWAVE IRRADIATION; PRIORITY JOURNAL; PROTON TRANSPORT; SUBSTITUTION REACTION; SUZUKI REACTION;

EID: 84870054755     PISSN: 00404020     EISSN: 14645416     Source Type: Journal    
DOI: 10.1016/j.tet.2012.10.019     Document Type: Article

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