Order and disorder: Differential structural impacts of myricetin and ethyl caffeate on human amylase, an antidiabetic target

Journal of Medicinal Chemistry

Volumn 55, Issue 22, 2012, Pages 10177-10186

  Williams, Leslie K ^a   Li, Chunmin ^a   Withers, Stephen G ^a   Brayer, Gary D ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA AMYLASE PANCREAS ISOENZYME; AMYLASE INHIBITOR; ANTIDIABETIC AGENT; CAFFEIC ACID; CAFFEIC ACID ETHYL ESTER; FLAVONOL DERIVATIVE; MYRICETIN; POLYPEPTIDE; UNCLASSIFIED DRUG;

ARTICLE; CRYSTAL STRUCTURE; DRUG STRUCTURE; ENZYME ACTIVE SITE; NONHUMAN; PREVALENCE; PROTEIN EXPRESSION;

BINDING SITES; CAFFEIC ACIDS; CATALYSIS; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; FLAVONOIDS; HUMANS; HYDROGEN BONDING; HYPOGLYCEMIC AGENTS; MODELS, MOLECULAR; PANCREATIC ALPHA-AMYLASES; PROTEIN CONFORMATION;

EID: 84870040447     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm301273u     Document Type: Article

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