Gastroprotective effect of Oxalis corniculata (whole plant) on experimentally induced gastric ulceration in Wistar rats

Indian Journal of Pharmaceutical Sciences

Volumn 74, Issue 1, 2012, Pages 48-53

  Sakat, S S ^a   Tupe, Preeti ^a   Juvekar, Archana ^a  

^a INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

Antiulcer; indomethacin; Oxalis corniculata; pylorus ligation; ranitidine

Indexed keywords

ANTIULCER AGENT; OXALIS CORNICULATA EXTRACT; PLANT EXTRACT; RANITIDINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIULCER ACTIVITY; ARTICLE; CONTROLLED STUDY; FEMALE; MALE; NONHUMAN; OXALIS CORNICULATA; PH; RAT; RATING SCALE; SCORING SYSTEM; STOMACH JUICE; STOMACH ULCER;

EID: 84870024083     PISSN: 0250474X     EISSN: 19983743     Source Type: Journal    
DOI: 10.4103/0250-474X.102543     Document Type: Article

References (33)

1. Sabiha S, Mohd AA, Asif M, Akhtar M. Role of phenolic compounds in peptic ulcer: An overview. J Pharm Bioallied Sci 2011;3:361-7.
2. Jainu M, Devi CS. Antiulcerogenic and ulcer healing effects of Solanum nigrum (L.) on experimental ulcer models: Possible mechanism for the inhibition of acid formation. J Ethnopharmacol 2006;104:156-63.
3. Lima ZP, Severi JA, Pellizzon CH, Brito AR, Solis PN, Caceres A, et al. Can the aqueous decoction of mango flowers be used as antiulcer agent? J Ethnopharmacol 2006;106:29-37.
4. Bighetti AE, Antonio MA, Kohn LK, Rehder VL, Foglio M, Possenti A, et al. Anti-ulcerogenic activity of a crude hydroalcoholic extract and coumarin isolated from Mikania laevigata Schultz Bip. Phytomedicine 2005;12:72-7.
5. Lakshimi V, Singh N, Shrivastva S, Mishra SK, Dharmani P, Palit G. Gedunian and photogedunin of Xilocarpus granatum show significant antisecretory effects and protect the gastric mucosa of peptic ulcer in rats. Phytomedicine 2009;17:569-74.
6. Chan FK, Leung WK. Peptic ulcer disease. Lancet 2002;360:933-41.
7. Ukwe CV, Ubaka CM, Madusqueuche J. Evaluation of the antiulcer activity of Olax subscorpioidea Oliv. Roots in rats. Asian Pac J Trop Med 2010;3; 13-16.
8. Joshi SG. Medicinal Plants. New Delhi: Oxford and IBH publishing Co. Pvt. Ltd.; 2000.
9. Arya VS. Indian Medicinal Plants. 1st ed. Vol. 4. Hyderabad: Orient Longman Ltd. Publication; 1995.
10. Kirtikar KR, Basu BD. Indian Medicinal Plants. 2nd ed. Vol. 1. Dehradun: International Book Distributors; 1935.
11. Tewari PV, Mapa HC, Chaturvedi C. Experimental study of estrogenic activity of certain indigenous drugs. J Res Indian Med Yoga Homeopath 1976;11:7-12.
12. Cambie RC, Ash J. Fijian Medicinal Plants. Australia: CSIRO; 1994. p. 234-5.
13. Achola KJ, Mwangi JW, Munenge RW. Pharmacological activity of Oxalis corniculata. Int J Pharmacogn 1995;33:247-9.
14. Sakat SS, Juvekar AR, Gambhire MN. In vitro antioxidant and antiinflammatory activity of methanol extract of Oxalis corniculata Linn. Int J Pharm Pharm Sci 2010;2:146-55.
15. Chetri DR, Parajuli S, Adhikari J. Antihepatopathic plants used by the Lepcha Tribe of the Sikkim and Darjeeling Himalayan Region of India. J Herbs Spices Med Plants 2008;18:27-35.
16. Abhilash PA, Nisha P, Prathapan A, Nampoothiri SV, Cherian OL, Sunitha TK, et al. Cardioprotective effects of aqueous extract of Oxalis corniculata in experimental myocardial infarction. Exp Toxicol Pathol 2011;63:535-40.
17. Farnsworth NR. Biological and phytochemical screening of plants. J Pharm Sci 1966;55:225-76.
18. Guidance document on acute oral toxicity testing" Series on testing and assessment No. 423. Organisation for economic co-operation and development, OECD Environment. Paris: Health and Safety Publications; 1996.
19. Muniappan M, Sundararaj T. Antiinflammatory and antiulcer activities of Bambusa arundinacea. J Ethnopharmacol 2003;88:161-7.
20. Shay H, Komarov SA, Fels SS, Meranze D, Grunstein M, Siplet H. A Simple method for uniform production of gastric ulcers in rats. Gastroenterol 1945;5:43-51.
21. Trease GE, Evans WC. Text Book of Pharmacognosy, 13th ed. London: Bailliere Tindall Publication; 1992.
22. Vogel HG, Vogel WH. Activity on the gastrointestinal tract. In: Drug discovery and evaluation (Pharmacological assays). Berlin: Springer Verlag Com pany; 1997. p. 486-7.
23. Aguwa CN, Mittal GC. Study of antiulcer activity of aqueous extract of leaves of Pyrenacantha standtii (Family I cacinaceae) using various models of experimental gastric ulcer in rats. Eur J Pharmacol 1981;74:215-19.
24. Muriel PB, Marivane L, Edson LM, Mateus FL, João PB, Jairo KB, et al. Evaluation of antiulcer activity of the main phenolic acids found in Brazilian Green Propolis. J Ethnopharmacol 2008;120:372-7.
25. Hoogerwerf WA, Pasricha PJ. Goodman and Gilman's The Pharmacological basis of therapeutics. In: Brunton, LL, Lazo JS, Parker KL, editors. Pharmacotherapy of gastric acidity, peptic ulcers, and gastroesophageal reflux disease. 11th ed. New York: McGraw-Hill Medical Publishing Division; 2006. p. 967-81.
26. Kumar A, Singh V, Chaudhary AK. Gastric antisecretory and antiulcer activities of Cedrus deodara (Roxb.) Loud. in Wistar rats. J Ethnopharmacol 2011;134:294-7.
27. Wallace JL. Mechanisms of protection and healing: Current knowledge and future research. Am J Med 2001;110:19S-22S.
28. Kushima H, Nishijima CM, Rodrigues CM, Rinaldo D, Sassa MF, Bauab TM. Davilla elliptica and Davilla nitida: Gastroprotective, antiinflammatory immunomodulatory and anti-Helicobacter pylori action. J Ethnopharmacol 2009;123:430-8.
29. Hayllar J, Bjarnason I. NSAIDs, COX-2 inhibitors, and the gut. Lancet 1995;346:521-2.
30. Malfertheiner P, Chan F K L, McColl K E L. Peptic ulcer disease. Lancet 2009;374:1149-61.
31. Parmar NS, Parmar S. Antiulcer potential of flavonoids. Indian J Physiol Pharmacol 1998;42:343-51.
32. Kahraman A, Erkasap NF, Köken T, Serteser M, Aktepe F, Erkasap S. The antioxidative and antihistaminic properties of quercetin in ethanolinduced gastric lesions. Toxicology 2003;183:133-42.
33. Francesca B, Angelo AI. The plant kingdom as a source of antiulcer remedies. Phytother Res 2000;14:581-91.