Blockade of the BAK Hydrophobic Groove by Inhibitory Phosphorylation Regulates Commitment to Apoptosis

PLoS ONE

Volumn 7, Issue 11, 2012, Pages

  Azad, Abul ^a   Fox, Joanna ^a   Leverrier, Sabrina ^a,b   Storey, Alan ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME C; PHOSPHOPROTEIN PHOSPHATASE 2A; PROTEIN BAK; PROTEIN BCL 2;

APOPTOSIS; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; CYTOKINE RELEASE; DNA DAMAGE; HUMAN; HUMAN CELL; MITOCHONDRION; PROTEIN BINDING; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MULTIMERIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION;

APOPTOSIS; BCL-2 HOMOLOGOUS ANTAGONIST-KILLER PROTEIN; CASPASE 3; CYTOCHROMES C; ENZYME ACTIVATION; HCT116 CELLS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MODELS, BIOLOGICAL; MODELS, MOLECULAR; PEPTIDE FRAGMENTS; PHOSPHORYLATION; PROTEIN CONFORMATION; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN MULTIMERIZATION; PROTEIN PHOSPHATASE 2; PROTO-ONCOGENE PROTEINS; SERINE; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84870003427     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0049601     Document Type: Article

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