Structural and functional insights into the role of the N-terminal Mps1 TPR domain in the SAC (spindle assembly checkpoint)

Biochemical Journal

Volumn 448, Issue 3, 2012, Pages 321-328

  Thebault, Philippe ^a   Chirgadze, Dimitri Y ^b   Dou, Zhen ^c   Blundell, Tom L ^b   Elowe, Sabine ^d   Bolanos Garcia, Victor M ^b,e  

^a University Laval   (Canada)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

^d UNIVERSITÉ LAVAL   (Canada)

^e OXFORD BROOKES UNIVERSITY   (United Kingdom)

Author keywords

Chromosome segregation; Crystal structure; Mitotic checkpoint; Monopolar spindle 1 (Mps1); Tetratricopeptide repeat motif (TPR motif)

Indexed keywords

BUB1 RELATED PROTEIN; DIMER; PHOSPHOTRANSFERASE; PROTEIN BUB1; PROTEIN KNL1; PROTEIN MPS1; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CENTROMERE; CRYSTAL STRUCTURE; DIMERIZATION; ENZYME REGULATION; HUMAN; HUMAN CELL; M PHASE CELL CYCLE CHECKPOINT; MITOSIS; MOLECULAR DOCKING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN MOTIF; TETRATRICOPEPTIDE REPEAT;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; AMINO ACID SEQUENCE; CELL CYCLE PROTEINS; CRYSTALLOGRAPHY, X-RAY; HEK293 CELLS; HELA CELLS; HETEROTRIMERIC GTP-BINDING PROTEINS; HUMANS; M PHASE CELL CYCLE CHECKPOINTS; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; REPETITIVE SEQUENCES, AMINO ACID;

EID: 84869986597     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20121448     Document Type: Article

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