Columbamine suppresses the proliferation and neovascularization of metastatic osteosarcoma U2OS cells with low cytotoxicity

Toxicology Letters

Volumn 215, Issue 3, 2012, Pages 174-180

  Bao, Meimei ^a   Cao, Zhifei ^a   Yu, Di ^a   Fu, Shilong ^a   Zhang, Gaochuan ^a   Yang, Ping ^a   Pan, Yanyan ^a   Yang, Bo ^b   Han, Hongyan ^c   Zhou, Quansheng ^a  

^a THE FIRST AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY   (China)

^b THE THIRD AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY   (China)

^c SOOCHOW UNIVERSITY   (China)

Author keywords

Columbamine; Neovascularization; Osteosarcoma; Toxicity; U2OS; Vasculogenic mimicry

Indexed keywords

COLUMBAMINE; COPTIS CHINENSIS EXTRACT; CYCLIN DEPENDENT KINASE 6; GELATINASE A; STAT3 PROTEIN;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL ADHESION; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; COPTIS CHINENSIS; CYTOTOXICITY; DOWN REGULATION; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; NEOVASCULARIZATION (PATHOLOGY); OSTEOSARCOMA CELL; PHASE TRANSITION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

ANTINEOPLASTIC AGENTS; BERBERINE ALKALOIDS; BONE NEOPLASMS; CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; HUMANS; MOLECULAR STRUCTURE; NEOPLASM INVASIVENESS; NEOVASCULARIZATION, PATHOLOGIC; OSTEOSARCOMA; PLANT EXTRACTS;

COPTIS CHINENSIS;

EID: 84869885235     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2012.10.015     Document Type: Article

References (53)

1. Baeten C.I., Hillen F., Pauwels P., de Bruine A.P., Baeten C.G. Prognostic role of vasculogenic mimicry in colorectal cancer. Diseases of the Colon and Rectum 2009, 52:2028-2035.
2. Bid H.K., Oswald D., Li C., London C.A., Lin J., Houghton P.J. Anti-angiogenic activity of a small molecule STAT3 inhibitor LLL12. PLoS One 2012, 7:e35513.
3. Briccoli A., Rocca M., Salone M., Guzzardella G.A., Balladelli A., Bacci G. High grade osteosarcoma of the extremities metastatic to the lung: long-term results in 323 patients treated combining surgery and chemotherapy, 1985-2005. Surgical Oncology 2010, 19:193-199.
4. Broadhead M.L., Clark J.C., Myers D.E., Dass C.R., Choong P.F. The molecular pathogenesis of osteosarcoma: a review. Sarcoma 2011, 2011:959248.
5. Bu Z., Pan Y., Shang B., Cao Z., Zhou Q., Ruan C. SZ-117, a monoclonal antibody against matrix metalloproteinase-2 inhibits tumor cell-mediated angiogenesis. Hybridoma (Larchmt) 2012, 31:63-67.
6. Cai X.S., Jia Y.W., Mei J., Tang R.Y. Tumor blood vessels formation in osteosarcoma: vasculogenesis mimicry. Chinese Medical Journal 2004, 117:94-98.
7. Carmeliet P., Jain R.K. Molecular mechanisms and clinical applications of angiogenesis. Nature 2011, 473:298-307.
8. Chen H.Y., Ye X.L., Cui X.L., He K., Jin Y.N., Chen Z., Li X.G. Cytotoxicity and antihyperglycemic effect of minor constituents from Rhizoma Coptis in HepG2 cells. Fitoterapia 2012, 83:67-73.
9. D'Adamo D.R. Appraising the current role of chemotherapy for the treatment of sarcoma. Seminars in Oncology 2011, 38(Suppl. 3):S19-S29.
10. der Schaft D.W., Hillen F.v., Pauwels P., Kirschmann D.A., Castermans K., Egbrink M.G., Tran M.G., Sciot R., Hauben E., Hogendoorn P.C., Delattre O., Maxwell P.H., Hendrix M.J., Griffioen A.W. Tumor cell plasticity in Ewing sarcoma, an alternative circulatory system stimulated by hypoxia. Cancer Research 2005, 65:11520-11528.
11. Feng Y., Zhang S., Tu J., Cao Z., Pan Y., Shang B., Liu R., Bao M., Guo P., Zhou Q. Novel function of scutellarin in inhibiting cell proliferation and inducing cell apoptosis of human Burkitt lymphoma Namalwa cells. Leukemia & Lymphoma 2012, 53:2456-2464.
12. Ferrari S., Palmerini E., Staals E.L., Mercuri M., Franco B., Picci P., Bacci G. The treatment of nonmetastatic high grade osteosarcoma of the extremity: review of the Italian Rizzoli experience. Impact on the future. Cancer Treatment and Research 2009, 152:275-287.
13. Fossey S.L., Bear M.D., Kisseberth W.C., Pennell M., London C.A. Oncostatin M promotes STAT3 activation, VEGF production, and invasion in osteosarcoma cell lines. BMC Cancer 2011, 11:125.
14. Fu D., He X., Yang S., Xu W., Lin T., Feng X. Zoledronic acid inhibits vasculogenic mimicry in murine osteosarcoma cell line in vitro. BMC Musculoskeletal Disorders 2011, 12:146.
15. Fujimoto A., Onodera H., Mori A., Nagayama S., Yonenaga Y., Tachibana T. Tumour plasticity and extravascular circulation in ECV304 human bladder carcinoma cells. Anticancer Research 2006, 26:59-69.
16. Hanahan D., Weinberg R.A. Hallmarks of cancer: the next generation. Cell 2011, 144:646-674.
17. Hess A.R., Margaryan N.V., Seftor E.A., Hendrix M.J. Deciphering the signaling events that promote melanoma tumor cell vasculogenic mimicry and their link to embryonic vasculogenesis: role of the Eph receptors. Developmental Dynamics 2007, 236:3283-3296.
18. Hess A.R., Seftor E.A., Gardner L.M., Carles-Kinch K., Schneider G.B., Seftor R.E., Kinch M.S., Hendrix M.J. Molecular regulation of tumor cell vasculogenic mimicry by tyrosine phosphorylation: role of epithelial cell kinase (Eck/EphA2). Cancer Research 2001, 61:3250-3255.
19. Honicke A.S., Ender S.A., Radons J. Combined administration of EGCG and IL-1 receptor antagonist efficiently downregulates IL-1-induced tumorigenic factors in U2OS human osteosarcoma cells. International Journal of Oncology 2012, 41:753-758.
20. Jiang J., Liu W., Guo X., Zhang R., Zhi Q., Ji J., Zhang J., Chen X., Li J., Zhang J., Gu Q., Liu B., Zhu Z., Yu Y. IRX1 influences peritoneal spreading and metastasis via inhibiting BDKRB2-dependent neovascularization on gastric cancer. Oncogene 2011, 30:4498-4508.
21. Leinonen T., Pirinen R., Bohm J., Johansson R., Kosma V.M. Increased expression of matrix metalloproteinase-2 (MMP-2) predicts tumour recurrence and unfavourable outcome in non-small cell lung cancer. Histology and Histopathology 2008, 23:693-700.
22. Letourneau P.A., Xiao L., Harting M.T., Lally K.P., Cox C.S., Andrassy R.J., Hayes-Jordan A.A. Location of pulmonary metastasis in pediatric osteosarcoma is predictive of outcome. Journal of Pediatric Surgery 2011, 46:1333-1337.
23. Li C., Lu N., Qi Q., Li F., Ling Y., Chen Y., Qin Y., Li Z., Zhang H., You Q., Guo Q. Gambogic acid inhibits tumor cell adhesion by suppressing integrin beta1 and membrane lipid rafts-associated integrin signaling pathway. Biochemical Pharmacology 2011, 82:1873-1883.
24. Li L., Chen P., Ling Y., Song X., Lu Z., He Q., Li Z., Lu N., Guo Q. Inhibitory effects of GL-V9 on the invasion of human breast carcinoma cells by downregulating the expression and activity of matrix metalloproteinase-2/9. European Journal of Pharmaceutical Sciences 2011, 43:393-399.
25. Li M., Gu Y., Zhang Z., Zhang S., Zhang D., Saleem A.F., Zhao X., Sun B. Vasculogenic mimicry: a new prognostic sign of gastric adenocarcinoma. Pathology Oncology Research 2010, 16:259-266.
26. Liu R., Cao Z., Tu J., Pan Y., Shang B., Zhang G., Bao M., Zhang S., Yang P., Zhou Q. Lycorine hydrochloride inhibits metastatic melanoma cell-dominant vasculogenic mimicry. Pigment Cell & Melanoma Research 2012, 25:630-638.
27. Liu W.B., Xu G.L., Jia W.D., Li J.S., Ma J.L., Chen K., Wang Z.H., Ge Y.S., Ren W.H., Yu J.H., Wang W., Wang X.J. Prognostic significance and mechanisms of patterned matrix vasculogenic mimicry in hepatocellular carcinoma. Medical Oncology 2011, 28(Suppl. 1):S228-S238.
28. Liu X., Hu Z., Shi Q., Zeng H., Shen Y., Jin H., Zhang W. Anti-inflammatory and anti-nociceptive activities of compounds from Tinospora sagittata (Oliv.) Gagnep. Archives of Pharmacal Research 2010, 33:981-987.
29. Liu X.S., Jiang J., Jiao X.Y., Wu Y.E., Lin J.H., Cai Y.M. Lycorine induces apoptosis and down-regulation of Mcl-1 in human leukemia cells. Cancer Letters 2009, 274:16-24.
30. Ma X., Yang Y., Wang Y., An G., Lv G. Small interfering RNA-directed knockdown of S100A4 decreases proliferation and invasiveness of osteosarcoma cells. Cancer Letters 2010, 299:171-181.
31. Maniotis A.J., Folberg R., Hess A., Seftor E.A., Gardner L.M., Pe'er J., Trent J.M., Meltzer P.S., Hendrix M.J. Vascular channel formation by human melanoma cells in vivo and in vitro: vasculogenic mimicry. American Journal of Pathology 1999, 155:739-752.
32. Mei J., Gao Y., Zhang L., Cai X., Qian Z., Huang H., Huang W. VEGF-siRNA silencing induces apoptosis, inhibits proliferation and suppresses vasculogenic mimicry in osteosarcoma in vitro. Experimental Oncology 2008, 30:29-34.
33. Mei J., Jia Y.W., Cai X.S. Vascular channel formation by osteosarcoma cells in vitro: vasculogenic mimicry. The Chinese-German Journal of Clinical Oncology 2003, 2:237-239.
34. Mirabello L., Troisi R.J., Savage S.A. Osteosarcoma incidence and survival rates from 1973 to 2004: data from the Surveillance, Epidemiology, and End Results Program. Cancer 2009, 115:1531-1543.
35. Misik V., Bezakova L., Malekova L., Kostalova D. Lipoxygenase inhibition and antioxidant properties of protoberberine and aporphine alkaloids isolated from Mahonia aquifolium. Planta Medica 1995, 61:372-373.
36. Osborne T.S., Khanna C. A review of the association between osteosarcoma metastasis and protein translation. Journal of Comparative Pathology 2012, 146:132-142.
37. Paulis Y.W., Soetekouw P.M., Verheul H.M., Tjan-Heijnen V.C., Griffioen A.W. Signalling pathways in vasculogenic mimicry. Biochimica et Biophysica Acta 2010, 1806:18-28.
38. Qian Q., Wang Q., Zhan P., Peng L., Wei S.Z., Shi Y., Song Y. The role of matrix metalloproteinase 2 on the survival of patients with non-small cell lung cancer: a systematic review with meta-analysis. Cancer Investigation 2010, 28:661-669.
39. Qu J.T., Wang M., He H.L., Tang Y., Ye X.J. The prognostic value of elevated vascular endothelial growth factor in patients with osteosarcoma: a meta-analysis and systemic review. Journal of Cancer Research and Clinical Oncology 2012, 138:819-825.
40. Ricci-Vitiani L., Pallini R., Biffoni M., Todaro M., Invernici G., Cenci T., Maira G., Parati E.A., Stassi G., Larocca L.M., De Maria R. Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells. Nature 2010, 468:824-828.
41. Sharma N., Seftor R.E., Seftor E.A., Gruman L.M., Heidger P.M., Cohen M.B., Lubaroff D.M., Hendrix M.J. Prostatic tumor cell plasticity involves cooperative interactions of distinct phenotypic subpopulations: role in vasculogenic mimicry. Prostate 2002, 50:189-201.
42. Shirakawa K., Kobayashi H., Heike Y., Kawamoto S., Brechbiel M.W., Kasumi F., Iwanaga T., Konishi F., Terada M., Wakasugi H. Hemodynamics in vasculogenic mimicry and angiogenesis of inflammatory breast cancer xenograft. Cancer Research 2002, 62:560-566.
43. Sood A.K., Seftor E.A., Fletcher M.S., Gardner L.M., Heidger P.M., Buller R.E., Seftor R.E., Hendrix M.J. Molecular determinants of ovarian cancer plasticity. American Journal of Pathology 2001, 158:1279-1288.
44. Stahl M., Ranft A., Paulussen M., Bolling T., Vieth V., Bielack S., Gortitz I., Braun-Munzinger G., Hardes J., Jurgens H., Dirksen U. Risk of recurrence and survival after relapse in patients with Ewing sarcoma. Pediatric Blood & Cancer 2011, 57:549-553.
45. Sun B., Zhang S., Zhao X., Zhang W., Hao X. Vasculogenic mimicry is associated with poor survival in patients with mesothelial sarcomas and alveolar rhabdomyosarcomas. International Journal of Oncology 2004, 25:1609-1614.
46. Wang R., Chadalavada K., Wilshire J., Kowalik U., Hovinga K.E., Geber A., Fligelman B., Leversha M., Brennan C., Tabar V. Glioblastoma stem-like cells give rise to tumour endothelium. Nature 2010, 468:829-833.
47. Wang Y.C., Zheng L.H., Ma B.A., Zhou Y., Zhang M.H., Zhang D.Z., Fan Q.Y. Clinical value of signal transducers and activators of transcription 3 (STAT3) gene expression in human osteosarcoma. Acta Histochemica 2011, 113:402-408.
48. Wright C.W., Marshall S.J., Russell P.F., Anderson M.M., Phillipson J.D., Kirby G.C., Warhurst D.C., Schiff P.L. In vitro antiplasmodial, antiamoebic, and cytotoxic activities of some monomeric isoquinoline alkaloids. Journal of Natural Products 2000, 63:1638-1640.
49. Wu S., Yu L., Cheng Z., Song W., Zhou L., Tao Y. Expression of maspin in non-small cell lung cancer and its relationship to vasculogenic mimicry. Journal of Huazhong University of Science and Technology. Medical Sciences 2012, 32:346-352.
50. Zhang L.Z., Mei J., Qian Z.K., Cai X.S., Jiang Y., Huang W.D. The role of VE-cadherin in osteosarcoma cells. Pathology Oncology Research 2010, 16:111-117.
51. Zhang S., Zhang D., Sun B. Vasculogenic mimicry: current status and future prospects. Cancer Letters 2007, 254:157-164.
52. Zhou Q., Kapoor M., Guo M., Belani R., Xu X., Kiosses W.B., Hanan M., Park C., Armour E., Do M.H., Nangle L.A., Schimmel P., Yang X.L. Orthogonal use of a human tRNA synthetase active site to achieve multifunctionality. Nature Structural & Molecular Biology 2010, 17:57-61.
53. Zhou Q., Kiosses W.B., Liu J., Schimmel P. Tumor endothelial cell tube formation model for determining anti-angiogenic activity of a tRNA synthetase cytokine. Methods 2008, 44:190-195.