Sitagliptin successfully ameliorates glycemic control in Werner syndrome with diabetes

Diabetes Care

Volumn 35, Issue 12, 2012, Pages

  Kitamoto, Takumi ^a   Takemoto, Minoru ^a   Fujimoto, Masaki ^a   Ishikawa, Takahiro ^a   Onishi, Shunichiro ^a   Okabe, Emiko ^a   Ishibashi, Ryoichi ^a   Kobayashi, Kazuki ^a   Kawamura, Harukiyo ^a   Yokote, Koutaro ^a  

^a CHIBA UNIVERSITY HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

C PEPTIDE; GLUCOSE; HEMOGLOBIN A1C; INSULIN; PIOGLITAZONE; SITAGLIPTIN;

ADULT; ARTICLE; BLOOD GLUCOSE MONITORING; BODY MASS; CASE REPORT; DIABETES MELLITUS; DIET RESTRICTION; DISEASE ASSOCIATION; DNA DETERMINATION; DRUG EFFICACY; FEMALE; GLUCAGON RELEASE; GLYCEMIC CONTROL; HUMAN; HYPERGLYCEMIA; INSULIN RELEASE; INTRAABDOMINAL FAT; OBESITY; POSTPRANDIAL STATE; TREATMENT OUTCOME; WEIGHT GAIN; WERNER SYNDROME;

BLOOD GLUCOSE; DIABETES MELLITUS; DIPEPTIDYL-PEPTIDASE IV INHIBITORS; FEMALE; HUMANS; MIDDLE AGED; PYRAZINES; TRIAZOLES; WERNER SYNDROME;

EID: 84869847319     PISSN: 01495992     EISSN: 19355548     Source Type: Journal    
DOI: 10.2337/dc12-1179     Document Type: Article

References (5)

1. Epstein CJ, Martin GM, Schultz AL, Motulsky AG. Werner's syndrome a review of its symptomatology, natural history, pathologic features, genetics and relationship to the natural aging process. Medicine (Baltimore) 1966;45:177-221
2. Yokote K, Hara K, Mori S, Kadowaki T, Saito Y, Goto M. Dysadipocytokinemia in Werner syndrome and its recovery by treatment with pioglitazone. Diabetes Care 2004;27:2562-2563 (Pubitemid 39281424)
3. Hattori S, Kasai M, Namatame T, Hattori Y, Kasai K. Pioglitazone treatment of insulin resistance in a patient with Werner's syndrome. Diabetes Care 2004;27:3021-3022 (Pubitemid 39565086)
4. Yamada K, Ikegami H, Yoneda H, Miki T, Ogihara T. All patients with Werner's syndrome are insulin resistant, but only those who also have impaired insulin secretion develop overt diabetes. Diabetes Care 1999;22:2094-2095 (Pubitemid 30434003)
5. Brown DW. Werner syndrome and genetic obesity: speculation. Med Hypotheses 1995;45:91-93