Melatonin-synthesizing enzymes and melatonin receptor in rat thyroid cells

Histology and Histopathology

Volumn 27, Issue 11, 2012, Pages 1429-1438

  García Marín, Rocío ^a   de Miguel, Manuel ^a   Fernández Santos, José Ma ^a   Carrillo Vico, Antonio ^b,c   Utrilla, José Carmelo ^a   Morillo Bernal, Jesús ^a   Díaz Parrado, Eduardo ^a   Rodríguez Prieto, Ismael ^b,c   Guerrero, Juan Miguel ^b,c   Martín Lacave, Inés ^a  

^a School of Medicine   (Spain)

^b HOSPITAL UNIVERSITARIO VIRGEN DEL ROCÍO   (Spain)

^c UNIVERSITY OF SEVILLE   (Spain)

Author keywords

C cells; Follicular cells; Melatonin; MT1; Thyroid

Indexed keywords

ACETYLSEROTONIN METHYLTRANSFERASE; ARALKYLAMINE ACETYLTRANSFERASE; MELATONIN; MELATONIN RECEPTOR;

ANIMAL; ARTICLE; BIOSYNTHESIS; CELL LINE; CYTOLOGY; ENZYMOLOGY; GENETICS; METABOLISM; RAT; THYROID GLAND;

ACETYLSEROTONIN O-METHYLTRANSFERASE; ANIMALS; ARYLALKYLAMINE N-ACETYLTRANSFERASE; CELL LINE; MELATONIN; RATS; RECEPTORS, MELATONIN; THYROID GLAND;

RATTUS;

EID: 84869838126     PISSN: 02133911     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (68)

1. Ahren B. (1991). Regulatory peptides in the thyroid gland: A review on their localization and function. Acta. Endocrinol. (Copenh.) 124, 225-232.
2. Ain K.B., Taylor K.D., Tofiq S. and Venkataraman G. (1997). Somatostatin receptor subtype expression in human thyroid and thyroid carcinoma cell lines. J. Clin. Endocrinol. Metab. 82, 1857-1862.
3. Aizawa S., Hoshino S., Sakata I., Adachi A., Yashima S., Hattori A. and Sakai T.J. (2007). Diurnal change of thyroid-stimulating hormone mRNA expression in the rat pars tuberalis. Neuroendocrinoly 11, 839-46.
4. Arias J., Scopsi L., Fischer J.A. and Larsson L.I. (1989). Light and electron-microscopical localization of calcitonin, calcitonin generelated peptide, somatostatin and C-terminal gastrin/cholecystokinin immunoreactivities in rat thyroid. Histochemistry 91, 265-272.
5. Axelrod J. and Weissbach H. (1960). Enzymatic O-methylation of Nacetylserotonin to melatonin. Science 29, 131-1312.
6. Barrett P., Fraser S., MacDonald A., Helliwell R.J.A. and Morgan P.J. (1994). Strategies for cloning and characterizing the melatonin and other G-protein coupled receptors expressed in the pars tuberalis. Adv. Pin. Res. 8, 309-319.
7. Carrillo-Vico A., Calvo J.R., Abreu P., Lardone P.J., García-Mauriño S., Reiter R.J. and Guerrero J.M. (2004). Evidence of melatonin synthesis by human lymphocytes and its physiological significance: possible role as intracrine, autocrine, and/or paracrine substance. FASEB J. 3, 537-539.
8. Carrillo-Vico A., Lardone P.J., Fernández-Santos J.M., Martín-Lacave I., Calvo J.R., Karasek M. and Guerrero J.M. (2005). Human lymphocyte-synthesized melatonin is involved in the regulation of the interleukin-2/interleukin-2 receptor system. J. Clin. Endocrinol. Metab. 2, 992-1000.
9. Cohn D.V., Elting J.J., Frick M. and Elde R. (1984). Selective localization of the parathyroid secretory protein-I/adrenal medulla chromogranin A protein family in a wide variety of endocrine cells of the rat. Endocrinology 114, 1963-1974
10. De Miguel M., Fernandez-Santos J.M., Utrilla J.C., Carrillo-Vico A., Borrero J., Conde E. and Martin-Lacave I. (2005). Thyrptropinreleasing hormone receptor expression in thyroid follicular cells: a new paragrine role of C-cells?. Histol. Histophatol. 20, 713-718.
11. Djeridane Y., Vivien-Roels B., Simonneaux V., Miguez J.M. and Pevet P. (1998). Evidence for melatonin synthesis in rodent Harderian gland: A dynamic in vitro study. J. Pineal Res. 25, 54-64.
12. Fekete C. and Lechan R.M. (2006). Neuroendocrine implications for the association between cocaine-and amphetamine regulated transcript (CART) and hypophysiotropic thyrotropinreleasing hormone (TRH). Peptides 27, 2012-2018.
13. Fekete C., Singru P.S., Sanchez E., Sarkar S., Christoffolete M.A., Riberio R.S., Rand W.M., Emerson C.H., Bianco A.C. and Lechan R.M. (2006). Differential effects of central leptin, insulin, or glucose administration during fasting on the hypothalamic-pituitary-thyroid axis and feeding-related neurons in the arcuate nucleus. Endocrinology 147, 520-529.
14. Fischer T.W., Slominski A., Zmijewski M.A., Reiter R.J. and Paus R. (2008). Melatonin as a major skin protectant: from free radical scavenging to DNA damage repair. Exp. Dermatol. 9, 713-30.
15. Gkonos P.J., Tavianini M.A., Liu C.C. and Roos B.A. (1989). Thyrotropin-releasing hormone gene expression in normal thyroid parafollicular cells. Mol. Endocrinol. 3, 2101-2109.
16. Grunditz T., Persson P., Hakanson R., Absood A., Böttcher G., Rerup C. and Sundler F. (1989). Helodermin-like peptides in thyroid C-cells: stimulation of thyroid hormone secretion and suppression of calcium incorporation into bone. Proc. Natl. Acad. Sci. USA 86, 1357-1361.
17. Guerrero J.M. and Reiter R.J. (2002). Melatonin-immune system relationships. Curr. Top. Med. Chem. 2, 167-79
18. Howard A.D., Feighner S.D. and Cully D.F. (1996). A receptor in pituitary and hypothalamus that functions in growth hormone release. Science 273, 974-977.
19. Itoh M.T., Ishizuka B., Kudo Y., Fusama S., Amemiya A. and Sumi Y. (1997). Detection of melatonin and serotonin N-acetyltransferase and hydroxyindole-O-methyltransferase activities in rat ovary. Mol. Cell. Endocrinol. 136, 7-13.
20. Itoh M.T., Ishizuka B., Kuribayashi Y., Amemiya A. and Sumi Y. (1999). Melatonin, its precursors, and synthesizing enzyme activities in the human ovary. Mol. Hum. Reprod. 5, 402-408.
21. Iuvone P.M., Brown A.D., Haque R., Weller J., Zawilska J.B., Chaurasia S.S., Ma M. and Klein D.C. (2002). Retinal melatonin production: Role of proteasomal proteolysis in the circadian and photic control of arylalkylamine N-acetyltransferase. Invest. Ophthalmol. Vis. Sci. 43, 564-572.
22. Kameda Y. (1987). Localization of immunoreactive calcitonin generelated peptide in thyroid c cells from various mammalian species. Anat. Rec. 219, 204-212.
23. Kameda Y., Oyama H., Endoh M. and Horino M. (1982). Somatostatin immunoreactive C cells in thyroid glands from various mammalian species. Anat. Rec. 204, 161-70.
24. Karbownik M. and Lewinski A. (2003a). The role of oxidative stree in physiological and pathological processes in the thyroid gland; possible involvement in pineal-thyroid interactions. Neuro. Endocrinol. Lett. 24, 293-303.
25. Karbownik M. and Lewinski A. (2003b). Melatonin reduces Fenton reaction-induced lipid peroxidation in porcine thyroid tissue. J. Cell. Biochem. 90, 806-11.
26. Konturek S.J., Konturek P.C., Brzozowska I., Pawlik M., Sliwowski Z., Czesnikiewicz-Guzik M., Kwiecien S., Brzozowski T., Bubenik G.A. and Pawlik W.W. (2007). Localization and biological activities of melatonin in intact and diseased gastrointestinal tract (GIT). J. Physiol. Pharmacol. 58, 381-405.
27. Kvetnoy I.M. (1999). Extrapineal melatonin: location and role within diffuse neuroendocrine system. Histochem. J. 31, 1-12
28. Korbonits M., Bustin S.A., Kojima M., Jordan S., Adams E.F., Lowe D.G., Kangawa K. and Grossman A. B.(2001). The expression of the growth hormone secretagogue receptor ligand ghrelin in normal and abnormal human pituitary and other neuroendocrine tumors. J. Clin. Endocrino. Metab. 86, 881-887.
29. Lewinski A. and Sewerynek E. (1986). Melatonin inhibits the basal and TSH-stimulated mitotic activity of thyroid follicular cells in vivo and in organ culture. J. Pineal Res. 3, 291-299.
30. Lewinski A. and Karbownik M. (2002). Melatonin and the thyroid gland. Neuro. Endocrinol. Lett. 1, 73-78.
31. Makay B., Makay O., Yenisey C., Icoz G., Ozgen G., Unsal E., Akyildiz M. and Yetkin E. (2009). The interaction of oxidative stress response with cytokines in the thyrotoxic rat: is there a link? Mediators. Inflamm. 2009, 391682.
32. Martín-Lacave I., Borrero M.J., Utrilla J.C., Fernández-Santos J.M., de Miguel M., Morillo J., Guerrero J.M., García-Marín R. and Conde E. (2009). C-cells evolve at the same rhythm as follicular cells when thyroidal status changes in rats. J. Anat. Mar. 214, 301-309.
33. Martinez-Cruz F., Pozo D., Osuna C., Espinar A., Marchante C. and Guerrero J.M. (2002). Oxidative stress induced by phenylketonuria in the rat: Prevention by melatonin, vitamin E, and vitamin C. J. Neurosci. Res. 69, 550-8.
34. McMillan P.J., Heiddbiichel U. and Vollrath L. (1985). Number and size of rat thyroid C cells: no effect of pinealectomy. Anat. Rec. 212, 167-171.
35. Mennenga K., Ueck M. and Reiter R.J. (1991). Immunohistological localization of melatonin in the pineal gland and retina of the rat. J. Pin. Res.10, 159-164.
36. Mocchegiani E., Santarelli L., Costarelli L., Cipriano C., Muti E., Giacconi R. and Malavolta M. (2006). Plasticity of neuroendocrinethymus interactions during ontogeny and ageing: role of zinc and arginine. Ageing Res. Rev. 5, 281-309.
37. Mogulkoc R., Baltaci A.K., Oztekin E., Aydin L. and Sivrikaya A. (2006). Melatonin prevents oxidant damage in various tissues of rats with hyperthyroidism. Life. Sci. 79, 311-315.
38. Morillo-Bernal J., Fernández-Santos J.M., Utrilla J.C., de Miguel M., García-Marín R. and Martín-Lacave I. (2009). Functional expression of the thyrotropin receptor in C cells: new insights into their involvement in the hypothalamic-pituitary-thyroid axis. J Anat. 215, 150-158.
39. Morillo-Bernal J., Fernández-Santos J.M., De Miguel M., García-Marín R., Gordillo-Martínez F., Díaz-Parrado E., Utrilla J.C. and Martín-Lacave I. (2011). Ghrelin potentiates TSH-induced expression of the thyroid tissue-specific genes thyroglobulin, thyroperoxidase and sodium-iodine symporter, in rat PC-Cl3 Cells. Peptides 32, 2333-2339.
40. Nakamura Y., Tamura H., Takayama H. and Kato H. (2003). Increased endogenous level of melatonin in preovulatory human follicles does not directly influence progesterone production. Fertil. Steril. 80, 1012-1016.
41. Naranjo M.C., Guerrero J.M., Rubio A., Lardone P.J., Carrillo-Vico A., Carrascosa-Salmoral M.P., Jiménez-Jorge S., Arellano M.V., Leal-Noval S.R., Leal M., Lissen E. and Molinero P. (2007). Melatonin biosynthesis in the thymus of humans and rats. Cell. Mol. Life. Sci. 64, 781-790.
42. Nitta K., Kito S., Kubota Y., Girgis S.I., Hillyard C.J., MacIntyre I. and Inagaki S. (1986). Ontogeny of calcitonin gene-related peptide and calcitonin in the rat thyroid. Histochemistry 84, 139-143.
43. Pévet P. (2000). Melatonin and biological rhythms. Signals Recept. 9, 203-212.
44. Raghay K., Garcia-Caballero T., Nogueiras R., Morel G., Beiras A., Diéguez C. and Gallego R. (2006). Ghrelin localization in rat and human thyroid and parathyroid glands and tumours. Histochem. Cell. Biol. 125, 239-246.
45. Raikhlin N.T., Kvetnoy I.M. and Tolkachev V.N. (1975). Melatonin may be synthesised in enterochromaffin cells. Nature 255, 344-345.
46. Rao M.V. and Chhunchha B. (2010). Protective role of melatonin against the mercury induced oxidative stress in the rat thyroid. Food Chem. Toxicol. 48, 7-10.
47. Reiter R.J., Paredes S.D., Manchester L.C. and Tan D.X. (2009). Reducing oxidative/nitrosative stress: a newly-discovered genre for melatonin. Crit. Rev. Biochem. Mol. Biol. 44, 175-200.
48. Reiter R.J., Tan D.X., Leon J., Kilic U. and Kilic E. (2005). When melatonin gets on your nerves: its beneficial actions in experimental models of stroke. Exp. Biol. Med. 230, 104-117.
49. Reiter R.J., Tan D.X., Mayo J.C., Sainz R.M. and Lopez-Burillo S. (2002). Melatonin, longevity and health in the aged: an assessment. Free. Radic. Res. 36, 1323-1329.
50. Sainz R.M., Mayo J.C., Reiter R.J., Tan D.X. and Rodriguez C. (2003). Apoptosis in primary lymphoid organs with aging. Microsc. Res. Tech. 62, 524-539.
51. Sallinen P., Saarela S., Jives M., Vakkuri O. and Leppäluoto J. (2005). The expression of MT1 and MT2 melatonin receptor mRNA in several rat tissues. Life. Sci. 76, 1123-1134.
52. Sawicki B. (1995). Evaluation of the role of mammalian thyroid parafollicular cells. Acta. Histochem. 97, 389-399.
53. Scopsi L., Pilotti S. and Rilke F. (1990). Immunocytochemical localization and identification of members of the pancreatic polypeptide (PP)-fold family in human thyroid C cells and medullary carcinomas. Regul. Pept. 30, 89-104.
54. Skinner M.M., Nass R., Lopes B., Laws E.R. and Thorner M.O. (1998). Growth hormone secretagogue receptor expression in human pituitary tumors. J. Clin. Endocrinol. Metab. 83, 4314-4320.
55. Slominski A., Wortsman J., Kohn L., Ain K.B., Venkataraman G.M., Pisarchik A., Chung J.H., Giuliani C., Thornton M., Slugocki G. and Tobin D.J. (2002). Expression of hypothalamic-pituitary-thyroid axis related genes in the human skin. J. Invest. Dermatol. 119, 1449-1455.
56. Tajes M., Gutierrez-Cuesta J., Ortuño-Sahagun D., Camins A. and Pallàs M. (2009). Anti-aging properties of melatonin in an in vitro murine senescence model: involvement of the sirtuin 1 pathway. J. Pineal Res. 47, 228-37.
57. Tamir H., Hsiung S.C., Yu P.Y., Liu K.P., Adlersberg M., Nunez E.A. and Gershon M.D. (1992). Serotonergic signalling between thyroid cells: protein kinase C and 5-HT2 receptors in the secretion and action of serotonin. Synapse 12, 155-168.
58. Tamir H., Hsiung S.C., Liu K.P., Blakely R.D., Russo A.F., Clark M.S., Nunez E.A. and Gershon M.D. (1996). Expression and development of a functional plasmalemmal 5-hydroxytryptamine transporter by thyroid follicular cells. Endocrinology 137, 4475-4486.
59. Tijmes M., Pedraza R. and Valladares L. (1996). Melatonin in the rat testis: evidence for local synthesis. Steroids 61, 65-68.
60. Tosini G., Davidson A.J., Fukuhara C., Kasamatsu M. and Castanon-Cervantes O. (2007). Localization of a circadian clock in mammalian photoreceptors. FASEB J. 21, 3866-3871.
61. Van Noorden S., Polak J.M., Negri L. and Pearse A.G. (1977). Common peptides in brain, intestine and skin: embryology, evolution and significance [proceedings]. J. Endocrinol. 75, 33-34.
62. Voisin P., Namboodiri M.A. and Klein D.C. (1984). Arylamine Nacetyltransferase and arylalkylamine N-acetyltransferase in the mammalian pineal gland. J. Biol. Chem. 259, 10913-10918.
63. Wierup N., Gunnarsdottir A., Ekblad E. and Sundler F. (2007). Characterisation of CART containing neurons and cells in the porcine pancreas, gastro-intestinal tract, adrenal and thyroid glands. BMC Neurosci. 8, 51.
64. Wright M.L., Cuthbert K.L., Donohue M.J., Solano S.D. and Proctor K.L. (2000). Direct influence of melatonin on the thyroid and comparison with prolactin. J. Exp. Zool. 286, 625-631.
65. Wright M.L., Pikula A., Babski A.M., Labieniec K.E. and Molan R.B. (1997). Effect of melatonin on the response of the thyroid to thyrotropin stimulation in vitro. Gen. Comp. Endocrinol. 108, 298-305.
66. Wurtman R.J. and Axelrod J. (1968). The formation, metabolism and physiologic effects of melatonin. Adv. Pharmacol. 6, 141-151.
67. Zabel M. (1984). Ultrastructural localization of calcitonin, somatostatin and serotonin in parafollicular cells of rat thyroid. Histochem. J. 16, 1265-1272.
68. Zabel M., Surdyk J. and Biela-Jacek I. (1987). Immunocytochemical studies on thyroid parafollicular cells in postnatal development of the rat. Acta. Anat. (Basel) 130, 251-256.