A validated microfluidics-based LC-chip-MS/MS method for the quantitation of fluoxetine and norfluoxetine in rat serum

Electrophoresis

Volumn 33, Issue 22, 2012, Pages 3370-3379

  Houbart, Virginie ^a   Servais, Anne Catherine ^a   Charlier, Thierry D ^a   Pawluski, Jodi L ^a,b   Abts, Frederic ^c   Fillet, Marianne ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b MAASTRICHT UNIVERSITY   (Netherlands)

^c AGILENT TECHNOLOGIES   (Belgium)

Author keywords

Fluoxetine; Mass spectrometry; Microfluidics; Pharmacokinetic study

Indexed keywords

BODY FLUIDS; MICROFLUIDICS; PHARMACOKINETICS; RATS; REGRESSION ANALYSIS;

CHIP DEVICES; FLUOXETINE; MICROFLUIDIC-BASED; MICROFLUIDICS SYSTEMS; NORFLUOXETINE; PHARMACOKINETIC STUDIES; RAT SERUM; SAMPLE VOLUME; SMALL ANIMAL; SMALL SAMPLES;

MASS SPECTROMETRY;

FLUOXETINE; NORFLUOXETINE;

ACCURACY; ARTICLE; BLOOD ANALYSIS; BLOOD SAMPLING; CATION EXCHANGE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG SCREENING; LIQUID CHROMATOGRAPHY; MICROFLUIDIC ANALYSIS; NONHUMAN; PROCESS DEVELOPMENT; PROCESS OPTIMIZATION; RAT; SENSITIVITY AND SPECIFICITY; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY; VALIDATION PROCESS;

EID: 84869821770     PISSN: 01730835     EISSN: 15222683     Source Type: Journal    
DOI: 10.1002/elps.201200168     Document Type: Article

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