Mechanistic basis for the effects of process parameters on quality attributes in high shear wet granulation

International Journal of Pharmaceutics

Volumn 439, Issue 1-2, 2012, Pages 324-333

  Badawy, Sherif I F ^a   Narang, Ajit S ^a   Lamarche, Keirnan ^a   Subramanian, Ganeshkumar ^a   Varia, Sailesh A ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

Compaction; Dissolution; Granulation parameters; Particle size; Porosity; Wet granulation

Indexed keywords

BMS 561389; BRIVANIB ALANINATE; PEXACERFONT; RAZAXABAN; UNCLASSIFIED DRUG; WATER;

ARTICLE; CRITICAL QUALITY ATTRIBUTE; DRUG GRANULATION; DRUG GRANULE; DRUG QUALITY; DRUG SOLUBILITY; FLOW KINETICS; IMPELLER; LIQUID; PARTICLE SIZE; POROSITY; POWDER; PRIORITY JOURNAL; TABLET HARDNESS;

ALANINE; DRUG COMPOUNDING; ISOXAZOLES; PARTICLE SIZE; POROSITY; POWDERS; PYRAZOLES; QUALITY CONTROL; SOLUBILITY; TABLETS; TECHNOLOGY, PHARMACEUTICAL; TRIAZINES; WATER;

EID: 84869502063     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.09.011     Document Type: Article

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