Effect of process parameters on compressibility of granulation manufactured in a high-shear mixer

International Journal of Pharmaceutics

Volumn 198, Issue 1, 2000, Pages 51-61

  Badawy, Sherif I Farag ^a   Menning, Mark M ^a   Gorko, Mary Ann ^a   Gilbert, Donna L ^a  

^a DUPONT COMPANY   (United States)

Author keywords

Compressibility; Granulation; High shear; Lactose; Porosity

Indexed keywords

CROSPOVIDONE; LACTULOSE; POVIDONE;

ARTICLE; DRUG GRANULATION; DRUG MIXTURE; PARTICLE SIZE; PHARMACEUTICAL ENGINEERING; POROSITY; PRIORITY JOURNAL; PROCESS CONTROL; SHEAR RATE; TABLET COMPRESSION; TABLET HARDNESS;

DRUG COMPOUNDING; DRUG INDUSTRY; HUMIDITY; LACTOSE; MICROSCOPY, ELECTRON, SCANNING; PARTICLE SIZE; POROSITY; POWDERS; REGRESSION ANALYSIS;

EID: 0034732296     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(99)00445-7     Document Type: Article

References (9)

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