Risk of retinoblastoma is associated with a maternal polymorphism in dihydrofolatereductase (DHFR) and prenatal folic acid intake

Cancer

Volumn 118, Issue 23, 2012, Pages 5912-5919

  Orjuela, Manuela A ^a,b   Cabrera Muñoz, Lourdes ^c   Paul, Ligi ^d   Ramirez Ortiz, Marco A ^c   Liu, Xinhua ^a   Chen, Jia ^e   Mejia Rodriguez, Fabiola ^f   Medina Sanson, Aurora ^c   Diaz Carreño, Silvia ^a   Suen, Ida H ^a   Selhub, Jacob ^d   Ponce Castañeda, M Veronica ^g  

^a Department of Medicine   (United States)

^b Hospital Infantil de Mexico ^*  (United States)

^c HOSPITAL INFANTIL DE MÉXICO FEDERICO GÓMEZ   (Mexico)

^d TUFTS UNIVERSITY   (United States)

^e MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^f INSTITUTO NACIONAL DE SALUD PÚBLICA   (Mexico)

^g HOSPITAL DE PEDIATRÍA   (Mexico)

Author keywords

childhood cancer; DHFR; dihydrofolatereductase; folic acid intake; retinoblastoma risk

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); DIHYDROFOLATE REDUCTASE; FOLIC ACID; THYMINE;

ADULT; AMINO ACID SUBSTITUTION; ARTICLE; CANCER RISK; CASE CONTROL STUDY; CHILD; CHILDHOOD CANCER; CONTROLLED STUDY; DATA ANALYSIS; DHFR GENE; FEMALE; GENE; GENE DELETION; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; HOMOZYGOSITY; HUMAN; INTERVIEW; INTRON; MAJOR CLINICAL STUDY; MEXICO; MTHFR GENE; POLYMERASE CHAIN REACTION; PRENATAL CARE; PRIORITY JOURNAL; RETINOBLASTOMA; SINGLE NUCLEOTIDE POLYMORPHISM; VITAMIN INTAKE; VITAMIN SUPPLEMENTATION;

CASE-CONTROL STUDIES; DIETARY SUPPLEMENTS; FEMALE; FOLIC ACID; GENE DELETION; GENOTYPE; HUMANS; POLYMORPHISM, SINGLE NUCLEOTIDE; PREGNANCY; RETINAL NEOPLASMS; RETINOBLASTOMA; RISK; TETRAHYDROFOLATE DEHYDROGENASE;

EID: 84869499862     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.27621     Document Type: Article

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