Pathologic significance of immunoglobulin G4-positive plasma cells in extrahepatic cholangiocarcinoma

Human Pathology

Volumn 43, Issue 12, 2012, Pages 2149-2156

  Kimura, Yasushi ^a   Harada, Kenichi ^a   Nakanuma, Yasuni ^a  

^a KANAZAWA UNIVERSITY   (Japan)

Author keywords

Cholangiocarcinoma; Cytotoxic T cell; IgG4; Regulatory T cell

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; IMMUNOGLOBULIN G4; TRANSCRIPTION FACTOR FOXP3;

AGED; ARTICLE; BILE DUCT CARCINOMA; CANCER SURGERY; CANCER TISSUE; CD8+ T LYMPHOCYTE; CELL INFILTRATION; CLINICAL ARTICLE; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPHOCYTE COUNT; MALE; OVERALL SURVIVAL; REGULATORY T LYMPHOCYTE;

AGED; BILE DUCT NEOPLASMS; BILE DUCTS, EXTRAHEPATIC; CHOLANGIOCARCINOMA; CHOLANGITIS, SCLEROSING; FEMALE; HUMANS; IMMUNOGLOBULIN G; MALE; PLASMA CELLS; T-LYMPHOCYTES, REGULATORY;

EID: 84869497162     PISSN: 00468177     EISSN: 15328392     Source Type: Journal    
DOI: 10.1016/j.humpath.2012.03.001     Document Type: Article

References (31)

1. H. Hamano, S. Kawa, and A. Horiuchi High serum IgG4 concentrations in patients with sclerosing pancreatitis N Engl J Med 344 2001 732 738
2. H. Hamano, S. Kawa, and Y. Ochi Hydronephrosis associated with retroperitoneal fibrosis and sclerosing pancreatitis Lancet 359 2002 1403 1404
3. Y. Zen, and Y. Nakanuma IgG4-related disease: a cross-sectional study of 114 cases Am J Surg Pathol 34 2010 1812 1819
4. T. Kamisawa, H. Nakajima, N. Egawa, N. Funata, K. Tsuruta, and A. Okamoto IgG4-related sclerosing disease incorporating sclerosing pancreatitis, cholangitis, sialadenitis and retroperitoneal fibrosis with lymphadenopathy Pancreatology 6 2006 132 137
5. S. Kitagawa, Y. Zen, and K. Harada Abundant IgG4-positive plasma cell infiltration characterizes chronic sclerosing sialadenitis (Kuttner's tumor) Am J Surg Pathol 29 2005 783 791
6. S. Kasashima, Y. Zen, and A. Kawashima Inflammatory abdominal aortic aneurysm: close relationship to IgG4-related periaortitis Am J Surg Pathol 32 2008 197 204
7. T. Saeki, A. Saito, and H. Yamazaki Tubulointerstitial nephritis associated with IgG4-related systemic disease Clin Exp Nephrol 11 2007 168 173
8. Y. Zen, D. Inoue, and A. Kitao IgG4-related lung and pleural disease: a clinicopathologic study of 21 cases Am J Surg Pathol 33 2009 1886 1893
9. Y. Zen, M. Onodera, and D. Inoue Retroperitoneal fibrosis: a clinicopathologic study with respect to immunoglobulin G4 Am J Surg Pathol 33 2009 1833 1839
10. K. Okazaki, K. Uchida, and T. Fukui Recent advances in autoimmune pancreatitis: concept, diagnosis, and pathogenesis J Gastroenterol 43 2008 409 418
11. Y. Nakanuma, and Y. Zen Pathology and immunopathology of immunoglobulin G4-related sclerosing cholangitis: the latest addition to the sclerosing cholangitis family Hepatol Res 37 Suppl 3 2007 S478 S486
12. K. Okazaki, K. Uchida, M. Matsushita, and M. Takaoka Autoimmune pancreatitis Intern Med 44 2005 1215 1223
13. T. Kamisawa, and A. Okamoto Autoimmune pancreatitis: proposal of IgG4-related sclerosing disease J Gastroenterol 41 2006 613 625
14. K. Okazaki, and T. Chiba Autoimmune related pancreatitis Gut 51 2002 1 4
15. H. Inoue, H. Miyatani, Y. Sawada, and Y. Yoshida A case of pancreas cancer with autoimmune pancreatitis Pancreas 33 2006 208 209
16. T. Kamisawa, P.Y. Chen, and Y. Tu Pancreatic cancer with a high serum IgG4 concentration World J Gastroenterol 12 2006 6225 6228
17. F. Sakashita, T. Tanahashi, and K. Yamaguchi Case of pancreatic tail cancer associated with auto-immune pancreatitis Jpn J Gastroenterol 39 2006 78 83
18. A. Raina, A.M. Krasinskas, and J.B. Greer Serum immunoglobulin G fraction 4 levels in pancreatic cancer: elevations not associated with autoimmune pancreatitis Arch Pathol Lab Med 132 2008 48 53
19. Y. Zen, T. Fujii, and K. Harada Th2 and regulatory immune reactions are increased in immunoglobin G4-related sclerosing pancreatitis and cholangitis Hepatology 45 2007 1538 1546
20. N. Hiraoka, K. Onozato, T. Kosuge, and S. Hirohashi Prevalence of FOXP3+ regulatory T cells increases during the progression of pancreatic ductal adenocarcinoma and its premalignant lesions Clin Cancer Res 12 2006 5423 5434
21. K. Isse, K. Harada, Y. Sato, and Y. Nakanuma Characterization of biliary intra-epithelial lymphocytes at different anatomical levels of intrahepatic bile ducts under normal and pathological conditions: numbers of CD4+CD28- intra-epithelial lymphocytes are increased in primary biliary cirrhosis Pathol Int 56 2006 17 24
22. A. Ghazale, S.T. Chari, and T.C. Smyrk Value of serum IgG4 in the diagnosis of autoimmune pancreatitis and in distinguishing it from pancreatic cancer Am J Gastroenterol 102 2007 1646 1653
23. D. Dhall, A.A. Suriawinata, L.H. Tang, J. Shia, and D.S. Klimstra Use of immunohistochemistry for IgG4 in the distinction of autoimmune pancreatitis from peritumoral pancreatitis Hum Pathol 41 2010 643 652
24. U. Motosugi, T. Ichikawa, and H. Yamaguchi Small invasive ductal adenocarcinoma of the pancreas associated with lymphoplasmacytic sclerosing pancreatitis Pathol Int 59 2009 744 747
25. H.C. Oh, J.G. Kim, and J.W. Kim Early bile duct cancer in a background of sclerosing cholangitis and autoimmune pancreatitis Intern Med 47 2008 2025 2028
26. K. Harada, S. Shimoda, and Y. Kimura Significance of IgG4-positive cells in extrahepatic cholangiocarcinoma: molecular mechanism of IgG4 reaction in cancer tissue Hepatology 2012 [in press]
27. A. Ghazale, S.T. Chari, and L. Zhang Immunoglobulin G4-associated cholangitis: clinical profile and response to therapy Gastroenterology 134 2008 706 715
28. S.T. Chari, T.C. Smyrk, and M.J. Levy Diagnosis of autoimmune pancreatitis: the Mayo Clinic experience Clin Gastroenterol Hepatol 4 2006 1010 1016 [quiz 1934]
29. P. Jeannin, S. Lecoanet, Y. Delneste, J.F. Gauchat, and J.Y. Bonnefoy IgE versus IgG4 production can be differentially regulated by IL-10 J Immunol 160 1998 3555 3561
30. K.T. Nouri-Aria, P.A. Wachholz, and J.N. Francis Grass pollen immunotherapy induces mucosal and peripheral IL-10 responses and blocking IgG activity J Immunol 172 2004 3252 3259
31. M. Koyabu, K. Uchida, and H. Miyoshi Analysis of regulatory T cells and IgG4-positive plasma cells among patients of IgG4-related sclerosing cholangitis and autoimmune liver diseases J Gastroenterol 45 2010 732 741