The effect of PKC phosphorylation on the "architectural" properties of HMGB1 protein

Molecular Biology Reports

Volumn 39, Issue 11, 2012, Pages 9947-9953

  Ugrinova, Iva ^a   Zlateva, Stanislava ^a   Pasheva, Evdokia ^a  

^a INSTITUTE OF MOLECULAR BIOLOGY   (Bulgaria)

Author keywords

Architectural factor; Distorted DNA; DNA bending; HMGB1 protein; PKC phosphorylation

Indexed keywords

CISPLATIN; DNA FRAGMENT; HIGH MOBILITY GROUP B1 PROTEIN; PROTEIN KINASE C;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DNA DAMAGE; ENZYME ACTIVITY; IN VITRO STUDY; PROTEIN DNA BINDING; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE;

ANIMALS; DNA; HMGB1 PROTEIN; HUMANS; LYSINE; PHOSPHORYLATION; PROTEIN KINASE C; PROTEIN PROCESSING, POST-TRANSLATIONAL; RATS;

EID: 84869493402     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-012-1863-x     Document Type: Article

References (38)

1. Bustin M (1999) Regulation of DNA-dependent activities by the functional motifs of the high-mobility-group chromosomal proteins. Mol Cell Biol 19: 5237-5246
2. Thomas JO, Travers AA (2001) HMG1 and 2, and related 'architectural' DNA-binding proteins. Trends Biochem Sci 26: 167-174
3. Ugrinova I, Zlateva S, Pashev IG, Pasheva EA (2009) Native HMGB1 protein inhibits repair of cisplatin-damaged nucleosomes in vitro. Int J Biochem Cell Biol 41: 1556-1562
4. Topalova D, Ugrinova I, Pashev IG, Pasheva EA (2008) HMGB1 protein inhibits DNA replication in vitro: a role of the acetylation and the acidic tail. Int J Biochem Cell Biol 40: 1536-1542
5. Bonaldi T, Langst G, Strohner R, Becker PB, Bianchi ME (2002) The DNA chaperone HMGB1 facilitates ACF/CHRACdependent nucleosome sliding. EMBO J 21: 6865-6873
6. Muller S, Scaffidi P, Degryse B, Bonaldi T, Ronfani L, Agresti A, Beltrame M, Bianchi ME (2001) New EMBO members' review: the double life of HMGB1 chromatin protein: architectural factor and extracellular signal. EMBO J 20: 4337-4340
7. Ugrinova I, Pasheva E, Armengaud J, Pashev IG (2001) In vivo acetylation of HMGB 1 protein enhances its binding affinity to distorted DNA structures. Biochemistry 41: 14655-14660
8. Ugrinova I, Mitkova E, Moskalenko C, Pashev IG, Pasheva E (2007) DNA bending versus DNA end joining activity of HMGB1 protein is modulated in vitro by acetylation. Biochemistry 46: 2111-2117
9. Mitkova E, Ugrinova I, Pashev IG, Pasheva EA (2005) The inhibitory effect of HMGB1 protein on the repair of cisplatindamaged DNA is accomplished through the acidic domain. Biochemistry 44: 5893-5898
10. Ugrinova I, Pashev IG, Pasheva EA (2009) Nucleosome binding properties and Co-remodeling activities of native and in vivo acetylated HMGB-1 and HMGB-2 proteins. Biochemistry 48: 6502-6507
11. Wisniewski J, Schulze E, Sapetto B (1994) DNA binding and nuclear translocation of insect high-mobility-group- protein-1 (HMG1) proteins are inhibited by phosphorylation. Eur J Biochem 255: 987-993
12. Wisniewski JR, Szewzuk Z, Petry I, Schwanbeck R, Renner U (1999) Constitutive phosphorylation of the acidic tails of the high mobility group 1 proteins by casein kinase II alters their conformation, stability, and DNA binding specificity. J Biol Chem 274: 20116-20122
13. Stemmer C, Schwanden A, Bauw G, Fojan P, Grasser KD (2002) Specificity of the stimulatory interaction between chromosomal HMGB proteins and the transcription factor Dof2 and its negative regulation by protein kinase CK2-mediated phosphorylation. J Biol Chem 277: 1092-1098
14. Alami-Ouahabi N, Veilleux S, Meistrich ML, Boissonneault G (1996) The testis-specific high mobility-group protein, a phosphorylation- dependent DNA packaging factor elongating and condensing spermatids. Mol Cell Biol 16: 3723-3729
15. Youn JH, Shin J (2006) Nucleocytoplasmic shuttling of HMGB1 is regulated by phosphorylation that redirects it toward secretion. J Immunol 177: 7889-7897
16. Oh YJ, Youn JH, Ji Y, Lee SE, Lim KJ, Choi JE, Shin JS (2009) HMGB1 is phosphorylated by classical protein kinase C and is secreted by a calcium-dependent mechanism. J Immunol 182: 5800-5809
17. Lotze MT, Tracey KJ (2005) High mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal. Nature Rev Immunol 5: 331-342
18. Poser I, Golob M, Buettner R, Bosserhoff A (2003) Upregulation of HMG1 leads to melanoma inhibitory activity expression in malignant melanoma cells and contributes to their malignancy phenotype. Mol Cell Biol 23: 2991-2998
19. Kang HJ, Lee H, Choi HJ, Youn JH, Shin JS, Ahn YH, Yoo JS, Paik YK, Kim H (2009) Non-histone nuclear factor HMGB1 is phosphorylated and secreted in colon cancers. Lab Invest 89: 948-959
20. Ugrinova I, Pasheva E, Armengaud J, Pashev IG (2001) In vivo acetylation of HMGB1 protein enhances its binding affinity to distorted DNA structures. Biochemistry 40: 14655-14660
21. Stedman JB, Bonner WM, West MHP (1980) Two dimensional gel analysis of acid extracts of nuclei, cells and tissues. Eur J Biochem 109: 17-23
22. Biade S, Sobol RW, Wilson SH, Matsumoto Y (1998) Impairment of proliferating cell nuclear antigen-dependent apurinic/apyrimidinic site repair on linear DNA. J Biol Chem 273: 898-902
23. Ugrinova I, Pashev IG, Pasheva EA (2011) Cyclin-dependent kinase 5 phosphorylates mammalian HMGB1 protein only if acetylated. J Biochem 149: 563-568
24. Herbert JM, Augereau JM, Gleye J, Maffrand JP (1990) Chelerythrine is a potent and specific inhibitor of protein kinase C. Biochem Biophys Res Commun 172: 993-999
25. Pelovsky P, Pashev IG, Pasheva EA (2009) Interplay between in vitro acetylation and phosphorylation of tailless HMGB1 protein. Biochem Biophys Res Commun 38: 138-142
26. Bianchi ME, Bertrame M, Paonessa G (1989) Specific recognition of cruciform DNA by nuclear protein HMG1. Science 243: 1056-1059
27. Bianchi ME, Falciola L, Ferrari S, Lilley DM (1992) The DNA binding site of HMG1 protein is composed of two similar segments (HMG boxes), both of which have counterparts in other eukaryotic regulatory proteins. EMBO J 11: 1055-1063
28. Pil PM, Lippard SJ (1992) Specific binding of chromosomal protein HMG1 to DNA damaged by the anticancer drug cisplatin. Science 256: 234-237
29. Pasheva EA, Pashev IG, Favre A (1988) Preferential binding of high mobility group 1 protein to UV damaged DNA. J Biol Chem 273: 34730-34736
30. Pil PM, Chow CS, Lippard SJ (1993) High-mobility-group 1 protein mediates DNA bending as determined by ring closures. Proc Natl Acad Sci USA 90: 9465-9469
31. Paul TT, Hakynson MJ, Johnson RC (1993) The nonspecific DNA-binding and -bending proteins HMG1 and HMG2 promote the assembly of complex nucleoprotein structures. Genes Dev 7: 1521-1534
32. Boonyaratanskornkit V, Melvin V, Prendergast P, Altmann M, Ronfani L, Bianchi ME, Taraseviciene L, Nordeen SK, Allegretto EA, Edwards DP (1998) High-mobility group chromatin proteins 1 and 2 functionally interact with steroid hormone receptors to enhance their DNA binding in vitro and transcriptional activity in mammalian cells. Mol Cell Biol 18: 4447-4487
33. ZappavignaV FalciolaL, Citterich MH, Mavillio F, Bianchi ME (1996) HMG1 interacts with HOX proteins and enhances their DNA binding and transcriptional activation. EMBO J 15: 4981-4991
34. Zwilling S, Konig H, Wirth T (1995) High mobility group protein 2 functionally interacts with the POU domains of octamer transcription factors. EMBO J 14: 1198-1208
35. Jayaraman L, Moorthy NC, Murthy KG, Manley JL, Bustin M, Prives C (1998) High mobility group protein-1 (HMG-1) is a unique activator of p53. Genes Dev 12: 462-472
36. Imamura T, Izumi H, Nagatani G, Ise T, Nomoto M, Iwamoto Y, Kohno K (2001) Interaction with p53 enhances binding of cisplatin- modified DNA by high mobility group 1 protein. J Biol Chem 276: 7534-7540
37. Sutrias-Grau M, Bianchi ME, Bernues J (1999) High mobility group protein 1 interacts specifically with the core domain of human TATA box-binding protein and interferes with transcription factor IIB within the pre-initiation complex. J Biol Chem 274: 1628-1634
38. Thomsen S, Franssen L, Launholt D, Fojan P, Grasser KD (2004) Interactions of the basic N-terminal and the acidic C-terminal domains of the maize chromosomal HMGB1 protein. Biochemistry 43: 8029-8037