Effect of polar protic and polar aprotic solvents on negative-ion electrospray ionization and chromatographic separation of small acidic molecules

Analytical Chemistry

Volumn 84, Issue 22, 2012, Pages 9942-9950

  Huffman, Brian A ^a   Poltash, Michael L ^a   Hughey, Christine A ^a  

^a JAMES MADISON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANALYTE RESPONSE; ANALYTES; APROTIC; CHROMATOGRAPHIC SEPARATIONS; COMPREHENSIVE STUDIES; ELECTRON WITHDRAWING GROUP; ELECTROSPRAYS; ENHANCED SENSITIVITY; EXTENDED CONJUGATION; FLOW INJECTION; INDUCTIVE EFFECTS; INSTRUMENT PERFORMANCE; LIQUID CHROMATOGRAPHY/MASS SPECTROMETRY; LOWER LIMITS OF DETECTIONS; METABOLOMICS; METHOD DEVELOPMENT; MOBILE PHASIS; MOBILE-PHASE COMPOSITION; POLAR APROTIC SOLVENT; PROTIC SOLVENTS; RETENTION TIME; SMALL MOLECULES; SOURCE CONDITIONS; TRIPLE QUADRUPOLE;

ACETONE; ACETONITRILE; ELECTROSPRAY IONIZATION; EXPERIMENTS; GAS CHROMATOGRAPHY; IONIZATION; LIQUID CHROMATOGRAPHY; METHANOL; MOLECULES; NEGATIVE IONS; SOLVENTS;

ORGANIC SOLVENTS;

EID: 84869476901     PISSN: 00032700     EISSN: 15206882     Source Type: Journal    
DOI: 10.1021/ac302397b     Document Type: Article

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