-
1
-
-
0031608723
-
Results of surgical treatment for recurrent hepatocellular carcinoma; comparison of outcome among patients with multicentric carcinogenesis, intrahepatic metastasis, and extrahepatic recurrence
-
Arii S, Monden K, Niwano M, et al: Results of surgical treatment for recurrent hepatocellular carcinoma; comparison of outcome among patients with multicentric carcinogenesis, intrahepatic metastasis, and extrahepatic recurrence. J Hepatobiliary Pancreat Surg 5: 86-92, 1998.
-
(1998)
J Hepatobiliary Pancreat Surg
, vol.5
, pp. 86-92
-
-
Arii, S.1
Monden, K.2
Niwano, M.3
-
2
-
-
47949116252
-
Sorafenib in advanced hepatocellular carcinoma
-
Llovet JM, Ricci S, Mazzaferro V, et al: Sorafenib in advanced hepatocellular carcinoma. N Engl J Med 359: 378-390, 2008.
-
(2008)
N Engl J Med
, vol.359
, pp. 378-390
-
-
Llovet, J.M.1
Ricci, S.2
Mazzaferro, V.3
-
3
-
-
37149003891
-
Management of hepatocellular carcinoma in Japan: Consensus-based clinical practice manual proposed by the Japan Society of Hepatology
-
Suppl
-
Kudo M and Okanoue T: Management of hepatocellular carcinoma in Japan: consensus-based clinical practice manual proposed by the Japan Society of Hepatology. Oncology 72 (Suppl 1): S2-S15, 2007.
-
(2007)
Oncology
, vol.72
, Issue.1
-
-
Kudo, M.1
Okanoue, T.2
-
4
-
-
0342314475
-
Combined therapy consisting of intraarterial cisplatin infusion and systemic interferon-alpha for hepatocellular carcinoma patients with major portal vein thrombosis or distant metastasis
-
Chung YH, Song IH, Song BC, et al: Combined therapy consisting of intraarterial cisplatin infusion and systemic interferon-alpha for hepatocellular carcinoma patients with major portal vein thrombosis or distant metastasis. Cancer 88: 1986-1991, 2000.
-
(2000)
Cancer
, vol.88
, pp. 1986-1991
-
-
Chung, Y.H.1
Song, I.H.2
Song, B.C.3
-
5
-
-
0036289092
-
Combination chemotherapy for advanced hepatocellular carcinoma complicated by major portal vein thrombosis
-
Suppl
-
Kaneko S, Urabe T and Kobayashi S: Combination chemotherapy for advanced hepatocellular carcinoma complicated by major portal vein thrombosis. Oncology 62 (Suppl 1): S69-S73, 2002.
-
(2002)
Oncology
, vol.62
, Issue.1
-
-
Kaneko, S.1
Urabe, T.2
Kobayashi, S.3
-
6
-
-
0037315472
-
Phase II trial of systemic continuous fuorouracil and subcutaneous recombinant interferon Alfa-2b for treatment of hepatocellular carcinoma
-
Patt YZ, Hassan MM, Lozano RD, et al: Phase II trial of systemic continuous fuorouracil and subcutaneous recombinant interferon Alfa-2b for treatment of hepatocellular carcinoma. J Clin Oncol 21: 421-427, 2003.
-
(2003)
J Clin Oncol
, vol.21
, pp. 421-427
-
-
Patt, Y.Z.1
Hassan, M.M.2
Lozano, R.D.3
-
7
-
-
33646383886
-
Combination therapy of intra-arterial 5-fuorouracil and systemic interferon-alpha for advanced hepatocellular carcinoma with portal venous invasion
-
Obi S, Yoshida H, Toune R, et al: Combination therapy of intra-arterial 5-fuorouracil and systemic interferon-alpha for advanced hepatocellular carcinoma with portal venous invasion. Cancer 106: 1990-1997, 2006.
-
(2006)
Cancer
, vol.106
, pp. 1990-1997
-
-
Obi, S.1
Yoshida, H.2
Toune, R.3
-
8
-
-
35148870112
-
Similar effects of recombinant interferon-alpha-2b and natural interferon-alpha when combined with intra-arterial 5-fuorouracil for the treatment of advanced hepatocellular carcinoma
-
Uka K, Aikata H, Takaki S, et al: Similar effects of recombinant interferon-alpha-2b and natural interferon-alpha when combined with intra-arterial 5-fuorouracil for the treatment of advanced hepatocellular carcinoma. Liver Int 27: 1209-1216, 2007.
-
(2007)
Liver Int
, vol.27
, pp. 1209-1216
-
-
Uka, K.1
Aikata, H.2
Takaki, S.3
-
9
-
-
0037080269
-
C o m b i n e d i n t r a a r t e r i a l 5 - f u o -rouracil and subcutaneous interferon-α therapy for advanced hepatocellular carcinoma with tumor thrombi in the major portal branches
-
Sakon M, Nagano H, Dono K, et al: C o m b i n e d i n t r a a r t e r i a l 5 - f u o -rouracil and subcutaneous interferon-α therapy for advanced hepatocellular carcinoma with tumor thrombi in the major portal branches. Cancer 94: 435-442, 2002.
-
(2002)
Cancer
, vol.94
, pp. 435-442
-
-
Sakon, M.1
Nagano, H.2
Dono, K.3
-
10
-
-
26944439521
-
Treatment of hepatocellular carcinoma with major portal vein thrombosis by combined therapy with subcutaneous interferon-alpha and intra-arterial 5-fuorouracil; role of type 1 interferon receptor expression
-
Ota H, Nagano H, Sakon M, et al: Treatment of hepatocellular carcinoma with major portal vein thrombosis by combined therapy with subcutaneous interferon-alpha and intra-arterial 5-fuorouracil; role of type 1 interferon receptor expression. Br J Cancer 93: 57-64, 2005.
-
(2005)
Br J Cancer
, vol.93
, pp. 57-64
-
-
Ota, H.1
Nagano, H.2
Sakon, M.3
-
12
-
-
0033941539
-
Augmentation of antitumor activity of 5-fuorouracil by interferon alpha is associated with up-regulation of p27Kip1 in human hepatocellular carcinoma cells
-
Eguchi H, Nagano H, Yamamoto H, et al: Augmentation of antitumor activity of 5-fuorouracil by interferon alpha is associated with up-regulation of p27Kip1 in human hepatocellular carcinoma cells. Clin Cancer Res 6: 2881-2890, 2000.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 2881-2890
-
-
Eguchi, H.1
Nagano, H.2
Yamamoto, H.3
-
13
-
-
9744276046
-
Partial contribution of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)/TRAIL receptor pathway to anti-tumor effects of interferon-alpha/5-fuorouracil against hepatocellular carcinoma
-
Yamamoto T, Nagano H, Sakon M, et al: Partial contribution of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)/TRAIL receptor pathway to anti-tumor effects of interferon-alpha/5-fuorouracil against hepatocellular carcinoma. Clin Cancer Res 10: 7884-7895, 2004.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 7884-7895
-
-
Yamamoto, T.1
Nagano, H.2
Sakon, M.3
-
14
-
-
19944430939
-
Combination of IFN-alpha and 5-fuorouracil induces apoptosis through IFN-alpha/beta receptor in human hepatocellular carcinoma cells
-
Kondo M, Nagano H, Wada H, et al: Combination of IFN-alpha and 5-fuorouracil induces apoptosis through IFN-alpha/beta receptor in human hepatocellular carcinoma cells. Clin Cancer Res 11: 1277-1286, 2005.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 1277-1286
-
-
Kondo, M.1
Nagano, H.2
Wada, H.3
-
15
-
-
35748985110
-
Role of the Fas/FasL pathway in combination therapy with interferon-alpha and fuo-rouracil against hepatocellular carcinoma in vitro
-
Nakamura M, Nagano H, Sakon M, et al: Role of the Fas/FasL pathway in combination therapy with interferon-alpha and fuo-rouracil against hepatocellular carcinoma in vitro. J Hepatol 46: 77-88, 2007.
-
(2007)
J Hepatol
, vol.46
, pp. 77-88
-
-
Nakamura, M.1
Nagano, H.2
Sakon, M.3
-
16
-
-
67349198077
-
Activation of Wnt/ beta-catenin signalling pathway induces chemoresistance to interferon-alpha/5-fuorouracil combination therapy for hepato-cellular carcinoma
-
Noda T, Nagano H, Takemasa I, et al: Activation of Wnt/ beta-catenin signalling pathway induces chemoresistance to interferon-alpha/5-fuorouracil combination therapy for hepato-cellular carcinoma. Br J Cancer 100: 1647-1658, 2009.
-
(2009)
Br J Cancer
, vol.100
, pp. 1647-1658
-
-
Noda, T.1
Nagano, H.2
Takemasa, I.3
-
17
-
-
70449627138
-
Combination of interferon-alpha and 5-fluorouracil inhibits endothelial cell growth directly and by regulation of angiogenic factors released by tumor cells
-
Wada H, Nagano H, Yamamoto H, et al: Combination of interferon-alpha and 5-fluorouracil inhibits endothelial cell growth directly and by regulation of angiogenic factors released by tumor cells. BMC Cancer 9: 361-372, 2009.
-
(2009)
BMC Cancer
, vol.9
, pp. 361-372
-
-
Wada, H.1
Nagano, H.2
Yamamoto, H.3
-
18
-
-
77952242309
-
Insulin-like growth factor-binding protein 7 alters the aensitivity to interferon-based anticancer therapy in hepatocellular carcinoma cells
-
Tomimaru Y, Eguchi H, Wada H, et al: Insulin-like growth factor-binding protein 7 alters the aensitivity to interferon-based anticancer therapy in hepatocellular carcinoma cells. Br J Cancer 102: 1483-1490, 2010.
-
(2010)
Br J Cancer
, vol.102
, pp. 1483-1490
-
-
Tomimaru, Y.1
Eguchi, H.2
Wada, H.3
-
19
-
-
78149469070
-
MicroRNA-21 induces resistance to the anti-tumor effect of interferon-α/5-fuorouracil in hepatocellular carcinoma cells
-
Tomimaru Y, Eguchi H, Nagano H, et al: MicroRNA-21 induces resistance to the anti-tumor effect of interferon-α/5-fuorouracil in hepatocellular carcinoma cells. Br J Cancer 103: 1617-1626, 2010.
-
(2010)
Br J Cancer
, vol.103
, pp. 1617-1626
-
-
Tomimaru, Y.1
Eguchi, H.2
Nagano, H.3
-
20
-
-
34047129082
-
Hepatic resection followed by IFN-alpha and 5-FU for advanced hepatocellular carcinoma with tumor thrombus in the major portal branch
-
Nagano H, Sakon M, Eguchi H, et al: Hepatic resection followed by IFN-alpha and 5-FU for advanced hepatocellular carcinoma with tumor thrombus in the major portal branch. Hepatogastroenterology 54: 172-179, 2007.
-
(2007)
Hepatogastroenterology
, vol.54
, pp. 172-179
-
-
Nagano, H.1
Sakon, M.2
Eguchi, H.3
-
21
-
-
36448942509
-
Interferon-α and 5-fuorouracil combination therapy following palliative hepatic resection in patients with advanced hepatocellular carcinoma, portal venous tumor thrombus in the major trunk and multiple nodules
-
Nagano H, Miyamoto A, Wada H, et al: Interferon-α and 5-fuorouracil combination therapy following palliative hepatic resection in patients with advanced hepatocellular carcinoma, portal venous tumor thrombus in the major trunk and multiple nodules. Cancer 110: 2493-2501, 2007.
-
(2007)
Cancer
, vol.110
, pp. 2493-2501
-
-
Nagano, H.1
Miyamoto, A.2
Wada, H.3
-
23
-
-
0020396015
-
Toxicity and response criteria of the Eastern Cooperative Oncology Group
-
Oken MM, Creech RH, Tormey DC, et al: Toxicity and response criteria of the Eastern Cooperative Oncology Group. Am J Clin Oncol 5: 649-655, 1982.
-
(1982)
Am J Clin Oncol
, vol.5
, pp. 649-655
-
-
Oken, M.M.1
Creech, R.H.2
Tormey, D.C.3
-
24
-
-
33845382806
-
Nonparametric estimation from incomplete observations
-
Kaplan EL and Meier P: Nonparametric estimation from incomplete observations. J Am Stat Assoc 53: 457-481, 1958.
-
(1958)
J Am Stat Assoc
, vol.53
, pp. 457-481
-
-
Kaplan, E.L.1
Meier, P.2
-
25
-
-
23044488917
-
Report of the 16th follow-up survey of primary liver cancer. The Liver Cancer Study Group of Japan
-
Ikai I, Arii S, Ichida T, et al: Report of the 16th follow-up survey of primary liver cancer. The Liver Cancer Study Group of Japan. Hepatol Res 32: 163-172, 2005.
-
(2005)
Hepatol Res
, vol.32
, pp. 163-172
-
-
Ikai, I.1
Arii, S.2
Ichida, T.3
-
26
-
-
0033053969
-
Clinical effcacy of portal vein stent placement in patients with hepatocellular carcinoma invading the main portal vein
-
Yamakado K, Tanaka N, Nakatsuka A, et al: Clinical effcacy of portal vein stent placement in patients with hepatocellular carcinoma invading the main portal vein. J Hepatol 30: 660-668, 1999.
-
(1999)
J Hepatol
, vol.30
, pp. 660-668
-
-
Yamakado, K.1
Tanaka, N.2
Nakatsuka, A.3
-
27
-
-
0031782818
-
A new prognostic system for hepatocellular carcinoma: A retrospective study of 435 patients
-
Cancer of the Liver Italian Program (CLIP) investigators
-
Cancer of the Liver Italian Program (CLIP) investigators: A new prognostic system for hepatocellular carcinoma: a retrospective study of 435 patients. Hepatology 28: 751-755, 1998.
-
(1998)
Hepatology
, vol.28
, pp. 751-755
-
-
-
28
-
-
0032767327
-
Hepatic resection with tumor thrombectomy for hepatocellular carcinoma with tumor thrombi in the major vasculature
-
Asahara T, Itamoto T, Katayama K, et al: Hepatic resection with tumor thrombectomy for hepatocellular carcinoma with tumor thrombi in the major vasculature. Hepatogastroenterology 46: 1862-1869, 1999.
-
(1999)
Hepatogastroenterology
, vol.46
, pp. 1862-1869
-
-
Asahara, T.1
Itamoto, T.2
Katayama, K.3
-
29
-
-
0034535296
-
Surgical results for hepatocellular carcinoma with macroscopic portal vein thrombosis
-
Ohkubo T, Yamamoto J, Sugawara Y, et al: Surgical results for hepatocellular carcinoma with macroscopic portal vein thrombosis. J Am Coll Surg 191: 657-660, 2000.
-
(2000)
J Am Coll Surg
, vol.191
, pp. 657-660
-
-
Ohkubo, T.1
Yamamoto, J.2
Sugawara, Y.3
-
30
-
-
0030804106
-
Hepatocellular carcinoma with portal vein tumor thrombus: Embolization of arterioportal shunts
-
Furuse J, Iwasaki M, Yoshino M, et al: Hepatocellular carcinoma with portal vein tumor thrombus: embolization of arterioportal shunts. Radiology 204: 787-790, 1997.
-
(1997)
Radiology
, vol.204
, pp. 787-790
-
-
Furuse, J.1
Iwasaki, M.2
Yoshino, M.3
-
31
-
-
15644382890
-
The safety and effcacy of trans-catheter arterial chemoembolization in the treatment of patients with hepatocellular carcinoma and main portal vein obstruction: A prospective controlled study
-
Lee HS, Kim JS, Choi IJ, et al: The safety and effcacy of trans-catheter arterial chemoembolization in the treatment of patients with hepatocellular carcinoma and main portal vein obstruction: a prospective controlled study. Cancer 79: 2087-2094, 1997.
-
(1997)
Cancer
, vol.79
, pp. 2087-2094
-
-
Lee, H.S.1
Kim, J.S.2
Choi, I.J.3
-
32
-
-
1642268463
-
Learning curve for radio-frequency ablation of liver tumors: Prospective analysis of initial 10 0 pat ients inatertiaryintiution
-
Poon RT, Ng KK, Lam CM, et al: Learning curve for radio-frequency ablation of liver tumors: prospective analysis of initial 10 0 pat ients i n a ter ti a r y i nst it ut ion. Ann Su rg 239: 4 41- 4 49, 2 0 04.
-
(2004)
Ann Su Rg
, vol.239
, Issue.4
, pp. 41-49
-
-
Poon, R.T.1
Ng, K.K.2
Lam, C.M.3
-
33
-
-
0345299824
-
Liver transplantation for the treatment of small hepatocellular carcinomas in patients with cirrhosis
-
Mazzaferro V, Regalia E, Doci R, et al: Liver transplantation for the treatment of small hepatocellular carcinomas in patients with cirrhosis. N Engl J Med 334: 693-700, 1996.
-
(1996)
N Engl J Med
, vol.334
, pp. 693-700
-
-
Mazzaferro, V.1
Regalia, E.2
Doci, R.3
-
34
-
-
85047689984
-
Prognosis after hepatic resection for stage I VA hepatocellular carcinoma: A need for reclassifcation
-
Poon RT, Fan ST, Ng IO and Wong J: Prognosis after hepatic resection for stage I VA hepatocellular carcinoma: a need for reclassifcation. Ann Surg 237: 376-383, 2003.
-
(2003)
Ann Surg
, vol.237
, pp. 376-383
-
-
Poon, R.T.1
Fan, S.T.2
Ng, I.O.3
Wong, J.4
-
35
-
-
0031911767
-
Surgical intervention for patients with stage IV-A hepatocellular carcinoma without lymph node metastasis proposal as a standard therapy
-
Ikai I, Yamaoka Y, Yamamoto Y, et al: Surgical intervention for patients with stage IV-A hepatocellular carcinoma without lymph node metastasis proposal as a standard therapy. Ann Surg 227: 433-439, 1998.
-
(1998)
Ann Surg
, vol.227
, pp. 433-439
-
-
Ikai, I.1
Yamaoka, Y.2
Yamamoto, Y.3
-
36
-
-
77954955081
-
Surgical treatment for hepatocellular carcinoma with portal vein tumor thrombus
-
Shi J, Lai ECH, Li N, et al: Surgical treatment for hepatocellular carcinoma with portal vein tumor thrombus. Ann Surg Oncol 17: 2073-2080, 2010.
-
(2010)
Ann Surg Oncol
, vol.17
, pp. 2073-2080
-
-
Shi, J.1
Lai, E.C.H.2
Li, N.3
-
37
-
-
0035722346
-
R a d i a t i o n t h e r a p y i n c o m b i n a t i o n with transcatheter arterial chemoembolization for hepatocellular carcinoma with extensive portal vein involvement
-
Tazawa J, Maeda M, Sakai Y, et al: R a d i a t i o n t h e r a p y i n c o m b i n a t i o n with transcatheter arterial chemoembolization for hepatocellular carcinoma with extensive portal vein involvement. J Gastroenterol Hepatol 16: 660-665, 2001.
-
(2001)
J Gastroenterol Hepatol
, vol.16
, pp. 660-665
-
-
Tazawa, J.1
Maeda, M.2
Sakai, Y.3
-
38
-
-
0036216375
-
Radiotherapy after transcatheter arterial chemoembolization for patients with hepatocellular carcinoma and portal vein tumor thrombus
-
Ishikura S, Ogino T, Furuse J, et al: Radiotherapy after transcatheter arterial chemoembolization for patients with hepatocellular carcinoma and portal vein tumor thrombus. Am J Clin Oncol 25: 189-193, 2002.
-
(2002)
Am J Clin Oncol
, vol.25
, pp. 189-193
-
-
Ishikura, S.1
Ogino, T.2
Furuse, J.3
-
39
-
-
0035118605
-
Selection criteria for hepatectomy in patients with hepatocellular carcinoma and portal vein tumor thrombus
-
Minagawa M, Makuuchi M, Takayama T and Ohtomo K: Selection criteria for hepatectomy in patients with hepatocellular carcinoma and portal vein tumor thrombus. Ann Surg 233: 379-384, 2001.
-
(2001)
Ann Surg
, vol.233
, pp. 379-384
-
-
Minagawa, M.1
Makuuchi, M.2
Takayama, T.3
Ohtomo, K.4
-
40
-
-
69249220328
-
Adjuvant transcatheter arterial chemoembolization improves effcacy of hepatectomy for patients with hepatocellular carcinoma and portal vein tumor thrombus
-
Peng BG, He Q, Li JP and Zhou F: Adjuvant transcatheter arterial chemoembolization improves effcacy of hepatectomy for patients with hepatocellular carcinoma and portal vein tumor thrombus. Am J Surg 198: 313-318, 2009.
-
(2009)
Am J Surg
, vol.198
, pp. 313-318
-
-
Peng, B.G.1
He, Q.2
Li, J.P.3
Zhou, F.4
-
41
-
-
42149116298
-
A pilot study of combination chemotherapy of S-1, a novel oral DPD inhibitor, and interferon-alpha for advanced hepatocellular carcinoma with extrahepatic metastasis
-
Nakamura M, Nagano H, Marubashi S, et al: A pilot study of combination chemotherapy of S-1, a novel oral DPD inhibitor, and interferon-alpha for advanced hepatocellular carcinoma with extrahepatic metastasis. Cancer 112: 1765-1771, 2008.
-
(2008)
Cancer
, vol.112
, pp. 1765-1771
-
-
Nakamura, M.1
Nagano, H.2
Marubashi, S.3
-
42
-
-
54449083925
-
Molecular targeted therapies in hepato-cellular carcinoma
-
Llovet JM and Bruix J: Molecular targeted therapies in hepato-cellular carcinoma. Hepatology 48: 1312-1327, 2008.
-
(2008)
Hepatology
, vol.48
, pp. 1312-1327
-
-
Llovet, J.M.1
Bruix, J.2
-
43
-
-
33749565425
-
High doses of tyrosine kinase inhibitor PTK787 enhance the effcacy of ischemic hypoxia for the treatment of hepatocellular carcinoma: Dual effects on cancer cell and angiogenesis
-
Yang ZF, Poon RT, Liu Y, et al: High doses of tyrosine kinase inhibitor PTK787 enhance the effcacy of ischemic hypoxia for the treatment of hepatocellular carcinoma: dual effects on cancer cell and angiogenesis. Mol Cancer Ther 5: 2261-2270, 2006.
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 2261-2270
-
-
Yang, Z.F.1
Poon, R.T.2
Liu, Y.3
-
44
-
-
67649946279
-
Effcacy, safety, and potential biomarkers of sunitinib monotherapy in advanced hepatocellular carcinoma: A phase II study
-
Zhu AX, Sahani DV, Duda DG, et al: Effcacy, safety, and potential biomarkers of sunitinib monotherapy in advanced hepatocellular carcinoma: a phase II study. J Clin Oncol 27: 3027-3035, 2009.
-
(2009)
J Clin Oncol
, vol.27
, pp. 3027-3035
-
-
Zhu, A.X.1
Sahani, D.V.2
Duda, D.G.3
-
45
-
-
79951558136
-
Ty r o s i n e kinase inhibitor PTK/ZK enhances the anti-tumor effects of interferon-α/5-fuorouracil therapy for hepatocellular carcinoma cells
-
Murakami M, Kobayashi S, Marubashi S, et al: Tyrosine kinase inhibitor PTK/ZK enhances the anti-tumor effects of interferon-α/5-fuorouracil therapy for hepatocellular carcinoma cells. Ann Surg Oncol 18: 589-596, 2011.
-
(2011)
Ann Surg Oncol
, vol.18
, pp. 589-596
-
-
Murakami, M.1
Kobayashi, S.2
Marubashi, S.3
|