Bambusae Caulis in Taeniam modulates neuroprotective and anti-neuroinflammatory effects in hippocampal and microglial cells via HO-1- and Nrf-2-mediated pathways

International Journal of Molecular Medicine

Volumn 30, Issue 6, 2012, Pages 1512-1520

  Eom, Hye Won ^a   Park, Sun Young ^a   Kim, Young Hun ^a   Seong, Su Jin ^a   Jin, Mei Ling ^a   Ryu, Eun Yeon ^a   Kim, Min Ju ^a   Lee, Sang Joon ^a  

^a Pusan National University   (South Korea)

Author keywords

Bambusae Caulis in Taeniam; Heme oxygenase 1; Hippocampal cells; Microglial cells; Nuclear erythroid 2 related factor 2

Indexed keywords

BAMBUSAE CAULIS IN TAENIAM ETHYL ACETATE; HEME OXYGENASE 1; HERBACEOUS AGENT; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; HIPPOCAMPUS; MICROGLIA; NEUROPROTECTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ALZHEIMER DISEASE; ANIMALS; ANTI-INFLAMMATORY AGENTS; BAMBUSA; CELL LINE; CELL SURVIVAL; CYTOKINES; DRUGS, CHINESE HERBAL; ENZYME INDUCTION; GLUTAMIC ACID; HEME OXYGENASE-1; HIPPOCAMPUS; INFLAMMATION MEDIATORS; LIPOPOLYSACCHARIDES; MEMBRANE PROTEINS; MICE; MICROGLIA; NEURONS; NEUROPROTECTIVE AGENTS; NF-E2-RELATED FACTOR 2; NITRITES; PROTEIN TRANSPORT; REACTIVE OXYGEN SPECIES; TRANSCRIPTIONAL ACTIVATION;

EID: 84869438180     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2012.1128     Document Type: Article

References (29)

1. Selkoe DJ: The molecular pathology of Alzheimer's disease. Neuron 6: 487-498, 1991.
2. Vina J, Lloret A, Giraldo E, Badia MC and Alonso MD: Antioxidant pathways in Alzheimer's disease: possibilities of intervention. Curr Pharm Des 17: 3861-3864, 2011.
3. Dheen ST, Kaur C and Ling EA: Microglial activation and its implications in the brain diseases. Curr Med Chem 14: 1189-1197, 2007. (Pubitemid 46739320)
4. Perry VH: The influence of systemic inflammation on inflammation in the brain: implications for chronic neurodegenerative disease. Brain Behav Immun 18: 407-413, 2004.
5. Jeong GS, Lee DS, Kwon TO, Lee HS, An RB and Kim YC: Cytoprotective constituents of the heartwood of Caesalpinia sappan on glutamate-induced oxidative damage in HT22 cells. Biol Pharm Bull 32: 945-949, 2009.
6. Murphy TH, Miyamoto M, Sastre A, Schnaar RL and Coyle JT: Glutamate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress. Neuron 2: 1547-1558, 1989.
7. Nguyen T, Nioi P and Pickett CB: The Nrf2-antioxidant response element signaling pathway and its activation by oxidative stress. J Biol Chem 284: 13291-13295, 2009.
8. Jiang T, Huang Z, Chan JY and Zhang DD: Nrf2 protects against As(III)-induced damage in mouse liver and bladder. Toxicol Appl Pharmacol 240: 8-14, 2009.
9. Li W and Kong AN: Molecular mechanisms of Nrf2-mediated antioxidant response. Mol Carcinog 48: 91-104, 2009.
10. Maines MD: The heme oxygenase system: a regulator of second messenger gases. Annu Rev Pharmacol Toxicol 37: 517-554, 1997.
11. Schipper HM: Heme oxygenase-1 in Alzheimer disease: a tribute to Moussa Youdim. J Neural Transm 118: 381-387, 2011.
12. Schipper HM, Song W, Zukor H, Hascalovici JR and Zeligman D: Heme oxygenase-1 and neurodegeneration: expanding frontiers of engagement. J Neurochem 110: 469-485, 2009.
13. Schipper HM: Heme oxygenase expression in human central nervous system disorders. Free Radic Biol Med 37: 1995-2011, 2004.
14. Shibata M, Yamatake Y, Sakamoto M, Kanamori M and Takagi K: Phamacological studies on bamboo grass (1). Acute toxicity and anti-inflammatory and antiulcerogenic activities of watersoluble fraction (Folin) extracted from Sasa albomarginata Makino et Shibata. Nihon Yakurigaku Zasshi 71: 481-490, 1975 (In Japanese).
15. Brown GC and Neher JJ: Inflammatory neurodegeneration and mechanisms of microglial killing of neurons. Mol Neurobiol 41: 242-247, 2010.
16. Shin DH, Shin JY, Kim SH, Kim JH, Chung HJ and Kim JC: Single oral dose toxicity study of Bambusae caulis in Taeniam in rats. J Toxicol and Public Health 20: 325-328, 2004 (In Korean).
17. Nakamura Y, Si QS and Kataoka K: Lipopolysaccharideinduced microglial activation in culture: temporal profiles of morphological change and release of cytokines and nitric oxide. Neurosci Res 35: 95-100, 1999. (Pubitemid 29518400)
18. Liu J, Li L and Suo WZ: HT22 hippocampal neuronal cell line possesses functional cholinergic properties. Life Sci 84: 267-271, 2009.
19. Meda L, Cassatella MA, Szendrei GI, Otvos L Jr, Baron P, Villalba M, Ferrari D and Rossi F: Activation of microglial cells by beta-amyloid protein and interferon-gamma. Nature 374: 647-650, 1995.
20. Fang J, Qin H, Seki T, Nakamura H, Tsukigawa K, Shin T and Maeda H: Therapeutic potential of pegylated hemin for reactive oxygen species-related diseases via induction of heme oxygenase-1: results from a rat hepatic ischemia/reperfusion injury model. J Pharmacol Exp Ther 339: 779-789, 2011.
21. Jung KA and Kwak MK: The Nrf2 system as a potential target for the development of indirect antioxidants. Molecules 15: 7266-7291, 2010.
22. Dennery PA: Regulation and role of heme oxygenase in oxidative injury. Curr Top Cell Regul 36: 181-199, 2000.
23. Surh YJ, Kundu JK, Li MH, Na HK and Cha YN: Role of Nrf2-mediated heme oxygenase-1 upregulation in adaptive survival response to nitrosative stress. Arch Pharm Res 32: 1163-1176, 2009.
24. Ben-Hur T, Ben-Menachem O, Furer V, Einstein O, Mizrachi-Kol and Grigoriadis N: Effects of proinflammatory cytokines on the growth, fate, and motility of multipotential neural precursor cells. Mol Cell Neurosci 24: 623-631, 2003. (Pubitemid 37506007)
25. Ekdahl CT, Claasen JH, Bonde S, Kokaia Z and Lindvall O: Inflammation is detrimental for neurogenesis in adult brain. Proc Natl Acad Sci USA 100: 13632-13637, 2003. (Pubitemid 37444791)
26. Seo T, Cha S, Kim TI, Lee JS and Woo KM: Porphyromonas gingivalis-derived lipopolysaccharide-mediated activation MAPK signaling regulates inflammatory response and differentiation in human periodontal ligament fibroblasts. J Microbiol 50: 311-319, 2012.
27. Ra J, Lee S, Kim HJ, Jang YP, Ahn H and Kim J: Bambusae Caulis in Taeniam extract reduces ovalbumin-induced airway inflammation and T helper 2 responses in mice. J Ethnopharmacol 128: 241-247, 2010.
28. Davies KJ: Oxidative stress: the paradox of aerobic life. Biochem Soc Symp 61: 1-31, 1995.
29. Maeda H and Akaike T: Oxygen free radicals as pathogenic molecules in viral diseases. Proc Soc Exp Biol Med 198: 721-727, 1991.