Gene silencing mediated by siRNA-binding fusion proteins is attenuated by double-stranded RNA-binding domain structure

Molecular Therapy Nucleic Acids

Volumn 1, Issue 11, 2012, Pages

  Geoghegan, James C ^a   Gilmore, Brian L ^a   Davidson, Beverly L ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

DRBD; protein transduction domain; RNA interference; siRNA delivery

Indexed keywords

CELL PENETRATING PEPTIDE; DOUBLE STRANDED RNA; HYBRID PROTEIN; PROTEIN KINASE R; SMALL INTERFERING RNA; TRANSFERRIN RECEPTOR;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; CYTOPLASM; DRUG DELIVERY SYSTEM; ENDOSOME; GENE SILENCING; HELA CELL; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN MOTIF; PROTEIN STRUCTURE; PROTEIN TARGETING; RNA BINDING; RNA INTERFERENCE;

EID: 84869399610     PISSN: None     EISSN: 21622531     Source Type: Journal    
DOI: 10.1038/mtna.2012.43     Document Type: Article

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