Putative relationship between hormonal status and serum pyrrolidone carboxypeptidase activity in pre- and post- menopausal women with breast cancer

Breast

Volumn 21, Issue 6, 2012, Pages 751-754

  Carrera González, María del Pilar ^a   Ramírez Expósito, María Jesús ^a   Dueñas, Basilio ^a   Martínez Ferrol, Julia ^a   Mayas, María Dolores ^a   Martínez Martos, José Manuel ^a  

^a UNIVERSITY OF JAÉN   (Spain)

Author keywords

Breast cancer; FSH; GnRH; LH; Post menopausal women; Pyrrolidone carboxypeptidase

Indexed keywords

FOLLITROPIN; GONADORELIN; LUTEINIZING HORMONE; PEPTIDE HYDROLASE; PYRROLIDONE CARBOXYPEPTIDASE; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BREAST CARCINOMA; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; FOLLITROPIN BLOOD LEVEL; HORMONE BLOOD LEVEL; HUMAN; LUTEINIZING HORMONE BLOOD LEVEL; MAJOR CLINICAL STUDY; POSTMENOPAUSE; PREMENOPAUSE; PRIORITY JOURNAL;

EID: 84869227109     PISSN: 09609776     EISSN: 15323080     Source Type: Journal    
DOI: 10.1016/j.breast.2012.02.001     Document Type: Article

References (13)

1. Hall J.E., Lavoie H.B., Marsh E.E., Martin K.A. Decrease in gonadotropin-releasing hormone (GnRH) pulse frequency with aging in postmenopausal women. J Clin Endocrinol Metab 2000, 85:1794-1800.
2. Hall J.E. Neuroendocrine changes with reproductive aging in women. Semin Reprod Med 2007, 25:344-351.
3. Schneider J., Martin-Gutierrez S., Tresguerres J.A., Garcia-Velasco J.A. Circulating estradiol defines the tumor phenotype in menopausal breast cancer patients. Maturitas 2009, 64:43-45.
4. Pujol P., Daures J.P., Brouillet J.P., Chang S., Rouanet P., Bringer J., et al. A prospective prognostic study of the hormonal milieu at the time of surgery in premenopausal breast carcinoma. Cancer 2001, 91:1854-1861.
5. Cummins P.M., O'Connor B. Pyroglutamyl peptidase; an overview of the three known enzymatic forms. Biochim Biophys Acta 1998, 429:1-17.
6. Beynon R., Bond J. Proteolytic Enzymes 2001, Oxford University Press, New York.
7. Carrera M.P., Ramirez-Exposito M.J., Valenzuela M.T., Garcia M.J., Mayas M.D., Martinez-Martos J.M. Serum pyrrolidone carboxypeptidase activity in N-methyl-nitrosourea induced rat breast cancer. Horm Metab Res 2003, 35:502-505.
8. Martinez J.M., Prieto I., Ramirez M.J., Cueva C., Alba F., Ramirez M. Aminopeptidase activities in breast cancer tissue. Clin Chem 1999, 45:1797-1802.
9. Kottler M.L., Starzec A., Carre M.C., Lagarde J.P., Martin A., Counis R. The genes for gonadotropin-releasing hormone and its receptor are expressed in human breast with fibrocystic disease and cancer. Int J Cancer 1997, 71:595-599.
10. Martinez J.M., Ramirez M.J., Prieto I., Petzelt C., Hermoso F., Alba F., et al. Human serum pyroglutamyl-beta-naphthylamide hydrolyzing activity during development and aging. Arch Gerontol Geriatr 1999, 28:31-36.
11. Sapoznik S., Cohen B., Tzuman Y., Meir G., Ben-Dor S., Harmelin A., et al. Gonadotropin-regulated lymphangiogenesis in ovarian cancer is mediated by LEDGF-induced expression of VEGF-C. Cancer Res 2009, 69:9306-9314.
12. Gill S., Sharpless J.L., Rado K., Hall J.E. Evidence that GnRH decreases with gonadal steroid feedback but increases with age in postmenopausal women. J Clin Endocrinol Metab 2002, 87:2290-2296.
13. Raheem S.N., Atoum M., Al-Hourani H., Rasheed M., Nimer N., Almuhrib T. Relationship between plasma progesterone, estradiol and prolactin concentrations and breast cancer in pre and postmenopausal women. Neoplasma 2010, 57:74-78.