Involvement of Wnt/p-catenin signaling in the osteogenesis of bone marrow mesenchymal stem cells induced by drynaria total flavonoids

National Medical Journal of China

Volumn 92, Issue 32, 2012, Pages 2288-2291

  Guo, Ying ^a   Li, Pei Fang ^c   Shu, Xiao Chun ^b   Deng, Huan ^c   Ma, Hai Li ^b   Sun, Liao ^b  

^a WEIFANG MEDICAL UNIVERSITY   (China)

^b SUN YAT SEN UNIVERSITY   (China)

^c NONE

Author keywords

Bone marrow mesenchymal stem cells; Drynaria total flavonoids; Osteogenic differentiation; Osteoporosis

Indexed keywords

ALKALINE PHOSPHATASE; BETA CATENIN; CYCLIN D; DRYNARIA TOTAL FLAVONOID; FLAVONOID; LYMPHOID ENHANCER FACTOR 1; MESSENGER RNA; UNCLASSIFIED DRUG; WNT PROTEIN;

ARTICLE; BONE DEVELOPMENT; ENZYME ACTIVITY; HEMATOPOIETIC STEM CELL; MESENCHYMAL STEM CELL; OSTEOBLAST; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; WNT SIGNALING PATHWAY; ANIMAL; BONE MARROW CELL; CELL DIFFERENTIATION; CYTOLOGY; DRUG EFFECT; MESENCHYMAL STROMA CELL; METABOLISM; POLYPODIACEAE; RAT; SPRAGUE DAWLEY RAT;

ANIMALS; BETA CATENIN; BONE MARROW CELLS; CELL DIFFERENTIATION; FLAVONOIDS; MESENCHYMAL STROMAL CELLS; OSTEOBLASTS; OSTEOGENESIS; POLYPODIACEAE; RATS; RATS, SPRAGUE-DAWLEY; WNT PROTEINS; WNT SIGNALING PATHWAY;

EID: 84869221065     PISSN: 03762491     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.0376-2491.2012.32.017     Document Type: Article

References (10)

1. 2010, 16: 652-654, 665.
2. 2008, 8: 19-20.
3. Westendorf J J, Kahler R A, Schroeder T M. Wnt signaling in osteoblasts and bone diseases. Gene, 2004, 341: 19-39.
4. Kengaku M, Capdevila J, Rodriguez-Esteban C, et al. Distinct WNT pathways regulating AER formation and dorsoventral polarity in the chick limb bud. Science, 1998, 280: 1274-1277.
5. 2010, 26: 1261-1264.
6. Orimo H. The mechanism of mineralization and the role of alkaline phosphatase in health and disease. J Nippon Med Sch, 2010, 77: 4-12.
7. 2010, 26: 990-992.
8. Zhang M, Yan Y, Lim Y B, et al. BMP-2 modulates beta-catenin signaling through stimulation of Lrp5 expression and inhibition of beta-TrCP expression in osteoblasts. J Cell Biochem, 2009, 108: 896-905.
9. Galindo M, Kahler R A, Teplyuk N M, et al. Cell cycle related modulations in Runx2 protein levels are independent of lymphocyte enhancer-binding factor 1 (Lef1) in proliferating osteoblasts. J Mol Histol, 2007, 38: 501-506.
10. 2010, 20: 684-688, 701.