Basal but not luminal mammary epithelial cells require PI3K/mTOR signaling for Ras-driven overgrowth

Cancer Research

Volumn 72, Issue 22, 2012, Pages 5856-5866

  Plichta, Kristin A ^a,b   Mathers, Jessica L ^a,b   Gestl, Shelley A ^a,b   Glick, Adam B ^b,c   Gunther, Edward J ^a,b  

^a PENN STATE CANCER INSTITUTE   (United States)

^b PENN STATE COLLEGE OF MEDICINE   (United States)

^c PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHATIDYLINOSITOL 3 KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CARCINOGENESIS; BREAST EPITHELIUM; CELL ASSAY; CELL COMPARTMENTALIZATION; CELL GROWTH; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CELL SURVIVAL; CELL TRANSFORMATION; CLONAL EVOLUTION; CONTROLLED STUDY; ENZYME INHIBITION; GENE ACTIVATION; GENE CONTROL; GENE REPRESSION; IMMUNOHISTOCHEMISTRY; INTRACELLULAR SIGNALING; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; ONCOGENE H RAS; PHENOTYPE; PRIORITY JOURNAL; VIDEO MICROSCOPY;

ANIMALS; BENZAMIDES; CELL GROWTH PROCESSES; CHROMONES; DIPHENYLAMINE; EPITHELIAL CELLS; FEMALE; IMMUNOHISTOCHEMISTRY; MAMMARY GLANDS, ANIMAL; MICE; MICE, TRANSGENIC; MITOGEN-ACTIVATED PROTEIN KINASES; MORPHOLINES; PHOSPHATIDYLINOSITOL 3-KINASES; RAS PROTEINS; TOR SERINE-THREONINE KINASES; TRANSGENES;

EID: 84869219913     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-12-1635     Document Type: Article

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