Elastolytic mechanism of a novel M23 metalloprotease pseudoalterin from deep-sea Pseudoalteromonas sp. CF6-2: Cleaving not only glycyl bonds in the hydrophobic regions but also peptide bonds in the hydrophilic regions involved in cross-linking

Journal of Biological Chemistry

Volumn 287, Issue 47, 2012, Pages 39710-39720

  Zhao, Hui Lin ^a   Chen, Xiu Lan ^a   Xie, Bin Bin ^a   Zhou, Ming Yang ^a   Gao, Xiang ^a   Zhang, Xi Ying ^a   Zhou, Bai Cheng ^a   Weiss, Anthony S ^b   Zhang, Yu Zhong ^a  

^a SHANDONG UNIVERSITY   (China)

^b UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CLEAVAGE SITES; DEEP SEA SEDIMENT; DEGRADATION MODEL; GENOME ANALYSIS; HIGH ACTIVITY; HYDROPHILIC REGIONS; HYDROPHOBIC REGIONS; INSOLUBLE PROTEINS; METALLO-PROTEASE; PEPTIDE BONDS; PSEUDOALTEROMONAS; SCANNING ELECTRON MICROSCOPIC; TROPOELASTIN;

HYDROPHOBICITY; PEPTIDES; SCANNING ELECTRON MICROSCOPY; SEDIMENTOLOGY; SEDIMENTS;

GLYCOPROTEINS;

ALANINE; DESMOSINE; DESMOSINE ALANYLALANINE; DESMOSINE ALANYLALANYLALANINE; ELASTIN; LYSINE; METALLOPROTEINASE; PEPTIDE DERIVATIVE; PSEUDOALTERIN; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DEEP SEA SPECIES; ELASTOLYSIS; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME DEGRADATION; ENZYME MECHANISM; ENZYME PURIFICATION; ENZYME SPECIFICITY; GENOME ANALYSIS; HYDROPHOBICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN CROSS LINKING; PROTEIN DEGRADATION; PROTEIN FAMILY; PSEUDOALTEROMONAS; SCANNING ELECTRON MICROSCOPY; SEDIMENT;

AMINO ACID SEQUENCE; ANIMALS; CATTLE; ELASTIN; METALLOPROTEASES; MOLECULAR SEQUENCE DATA; OCEANS AND SEAS; PSEUDOALTEROMONAS; SEAWATER; WATER MICROBIOLOGY;

BOVINAE; PSEUDOALTEROMONAS SP.; VERTEBRATA;

EID: 84869209148     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.405076     Document Type: Article

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