Pregnancy Is Associated with Decreased Cardiac Proteasome Activity and Oxidative Stress in Mice

PLoS ONE

Volumn 7, Issue 11, 2012, Pages

  Iorga, Andrea ^a   Dewey, Shannamar ^b   Partow Navid, Rod ^a   Gomes, Aldrin V ^b   Eghbali, Mansoureh ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MEMBRANE PROTEIN; PROTEASOME; PROTEIN BETA5I; PROTEIN PA28ALPHA; PROTEIN RPN2; PROTEIN RPT4; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; GENETIC TRANSCRIPTION; HEART HYPERTROPHY; HEART STRESS; MOUSE; NONHUMAN; OXIDATIVE STRESS; PREGNANCY; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN LOCALIZATION; REAL TIME POLYMERASE CHAIN REACTION; UBIQUITINATION;

ANALYSIS OF VARIANCE; ANIMALS; BLOTTING, WESTERN; CARDIOMEGALY; DIESTRUS; DNA PRIMERS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; IMMUNOHISTOCHEMISTRY; MICE; MICROSCOPY, CONFOCAL; MYOCARDIUM; OXIDATIVE STRESS; POSTPARTUM PERIOD; PREGNANCY; PROTEASOME ENDOPEPTIDASE COMPLEX; REACTIVE OXYGEN SPECIES; REAL-TIME POLYMERASE CHAIN REACTION; UBIQUITINATION;

MUS;

EID: 84869209008     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0048601     Document Type: Article

References (29)

1. Mone SM, Sanders SP, Colan SD, (1996) Control mechanisms for physiological hypertrophy of pregnancy. Circulation 94: 667-72.
2. Dorn GW, Robbins J, Sugden PH, (2003) Phenotyping hypertrophy: eschew obfuscation. Circ Res 92: 1171-5.
3. Daniels SR, Meyer RA, Liang YC, Bove KE, (1988) Echocardiographically determined left ventricular mass index in normal children, adolescents and young adults. J Am Coll Cardiol 12: 703-8.
4. Pluim BM, Zwinderman AH, van der LA, van der Wall EE, (2000) The athlete's heart. A meta-analysis of cardiac structure and function. Circulation 101: 336-44.
5. Schannwell CM, Zimmermann T, Schneppenheim M, Plehn G, Marx R, et al. (2002) Left ventricular hypertrophy and diastolic dysfunction in healthy pregnant women. Cardiology 97: 73-8.
6. Predmore JM, Wang P, Davis F, Bartolone S, Westfall MV, et al. (2010) Ubiquitin proteasome dysfunction in human hypertrophic and dilated cardiomyopathies. Circulation 121: 997-1004.
7. Glickman MH, Ciechanover A, (2002) The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction. Physiol Rev 82: 373-428.
8. Glickman MH, Raveh D, (2005) Proteasome plasticity. FEBS Lett 579: 3214-23.
9. Gomes AV, Zong C, Ping P, (2006) Protein degradation by the 26S proteasome system in the normal and stressed myocardium. Antioxid Redox Signal 8: 1677-91.
10. Hochstrasser M, (1996) Ubiquitin-dependent protein degradation. Annu Rev Genet 30: 405-39.
11. Mearini G, Schlossarek S, Willis MS, Carrier L, (2008) The ubiquitin-proteasome system in cardiac dysfunction. Biochim Biophys Acta 1782: 749-63.
12. Drews O, Tsukamoto O, Liem D, Streicher J, Wang Y, et al. (2006) Differential regulation of proteasome function in isoproterenol-induced cardiac hypertrophy. Circ Res 107: 1094-101.
13. Zong C, Gomes AV, Drews O, Li X, Young GW, et al. (2006) Regulation of murine cardiac 20S proteasomes: role of associating partners. Circ Res 99: 372-80.
14. Gomes AV, Young GW, Wang Y, Zong C, Eghbali M, et al. (2009) Contrasting proteome biology and functional heterogeneity of the 20 S proteasome complexes in mammalian tissues. Mol Cell Proteomics 8: 302-15.
15. Eghbali M, Deva R, Alioua A, Minosyan TY, Ruan H, et al. (2005) Molecular and functional signature of heart hypertrophy during pregnancy. Circ Res 96: 1208-16.
16. Bader N, Grune T, (2006) Protein oxidation and proteolysis. Biol Chem 387: 1351-5.
17. Eghbali M, Wang Y, Toro L, Stefani E, (2006) Heart hypertrophy during pregnancy: a better functioning heart? Trends Cardiovasc Med 16: 285-91.
18. Li YF, Wang, (2011) The role of the proteasome in heart disease. Biochim Biophys Acta 1809: 141-9.
19. Tsukamoto O, Minamino T, Okada K, Shintani Y, Takashima S, et al. (2006) Depression of proteasome activities during the progression of cardiac dysfunction in pressure-overloaded heart of mice. Biochem Biophys Res Commun 340: 1125-33.
20. Depre C, Wang Q, Yan L, Hedhli N, Peter P, et al. (2006) Activation of the cardiac proteasome during pressure overload promotes ventricular hypertrophy. Circulation 114: 1821-8.
21. Hedhli N, Lizano P, Hong C, Fritzky LF, Dhar SK, et al. (2008) Proteasome inhibition decreases cardiac remodeling after initiation of pressure overload. Am J Physiol Heart Circ Physiol 295: H1385-H1393.
22. Otsuka K, Terasaki F, Shimomura H, Tsukada B, Horii T, et al. (2010) Enhanced expression of the ubiquitin-proteasome system in the myocardium from patients with dilated cardiomyopathy referred for left ventriculoplasty: an immunohistochemical study with special reference to oxidative stress. Heart Vessels 25: 474-84.
23. Liu CW, Li X, Thompson D, Wooding K, Chang TL, et al. (2006) ATP binding and ATP hydrolysis play distinct roles in the function of 26S proteasome. Mol Cell 24: 39-50.
24. Goldberg AL, (2003) Protein degradation and protection against misfolded or damaged proteins. Nature 426: 895-9.
25. Li YP, Chen Y, Li AS, Reid MB, (2003) Hydrogen peroxide stimulates ubiquitin-conjugating activity and expression of genes for specific E2 and E3 proteins in skeletal muscle myotubes. Am J Physiol Cell Physiol 285: C806-C812.
26. Seifert U, Bialy LP, Ebstein F, Bech-Otschir D, Voigt A, et al. (2010) Immunoproteasomes preserve protein homeostasis upon interferon-induced oxidative stress. Cell 142: 613-24.
27. Hamel FG, Fawcett J, Bennett RG, Duckworth WC, (2004) Control of proteolysis: hormones, nutrients, and the changing role of the proteasome. Curr Opin Clin Nutr Metab Care 7: 255-8.
28. Lee DH, Goldberg AL, (1998) Proteasome inhibitors: valuable new tools for cell biologists. Trends Cell Biol 8: 397-403.
29. Kazi A, Daniel KG, Smith DM, Kumar NB, Dou QP, (2003) Inhibition of the proteasome activity, a novel mechanism associated with the tumor cell apoptosis-inducing ability of genistein. Biochem Pharmacol 66: 965-76.