Moral decision-making in polysubstance dependent individuals

Drug and Alcohol Dependence

Volumn 126, Issue 3, 2012, Pages 389-392

  Carmona Perera, Martina ^a   Verdejo García, Antonio ^a,b   Young, Liane ^c   Molina Fernández, Antonio ^d   Pérez García, Miguel ^a,b  

^a UNIVERSITY OF GRANADA   (Spain)

^b Biomedical Research Center CIBM   (Spain)

^c BOSTON COLLEGE   (United States)

^d Asociación Proyecto Hombre   (Spain)

Author keywords

Emotion; Moral judgment; Polysubstance dependent individuals

Indexed keywords

3,4 METHYLENEDIOXYMETHAMPHETAMINE; ALCOHOL; CANNABIS; COCAINE; DIAMORPHINE;

ADULT; ALCOHOL CONSUMPTION; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE ASSOCIATION; DRUG DEPENDENCE; EMOTION; HUMAN; MALE; MORALITY; PATIENT DECISION MAKING; PERCEPTION; PRIORITY JOURNAL;

ADULT; ALCOHOLISM; CASE-CONTROL STUDIES; COCAINE-RELATED DISORDERS; DECISION MAKING; HEROIN DEPENDENCE; HUMANS; INTERVIEW, PSYCHOLOGICAL; JUDGMENT; MALE; MORALS; N-METHYL-3,4-METHYLENEDIOXYAMPHETAMINE; SEVERITY OF ILLNESS INDEX; STREET DRUGS; SUBSTANCE-RELATED DISORDERS;

EID: 84869209002     PISSN: 03768716     EISSN: 18790046     Source Type: Journal    
DOI: 10.1016/j.drugalcdep.2012.05.038     Document Type: Article

References (38)

1. Aguilar de Arcos F., Verdejo-García A., López J., Montañez M., Arráez F., Pérez-García M. Respuesta emocional ante estímulos afectivos en sujetos adictos a opiáceos bajo consumo controlado en el P.E.P.S.A. Adicciones 2007, 20:27-36.
2. Aguilar de Arcos F., Verdejo-García A., Peralta-Ramírez M.I., Sánchez-Barrera M., Pérez-García M. Experience of emotions in substance abuser exposed to images containing neutral, positive and negative affective stimuli. Drug Alcohol Depend. 2005, 30:89-101.
3. Bechara A., Damasio H., Damasio A.R. Emotion, decision making, and the orbitofrontal cortex. Cereb. Cortex 2000, 10:295-307.
4. Bechara A., Dolan S., Hindes A. Decision-making and addiction (part II): miopia for the future or hypersensitivity to reward?. Neuropsychologia 2002, 40:1609-1705.
5. Carmona-Perera M., Verdejo-García A., Pérez-García M. Adaptación a la población española de dos instrumentos de juicios morales 2009, Universidad de Granada, Granada.
6. Ciaramelli E., Muccioli M., Làdavas E., Di Pellegrino G. Selective deficit in personal moral judgment following damage to ventromedial prefrontal cortex. Soc. Cogn. Affect. Neurosci. 2007, 2:84-92.
7. Crockett M.J., Clark L., Hauser M.D., Robbins T.W. Serotonin selectively influences moral judgment and behavior through effects on harm aversion. Proc. Natl. Acad. Sci. U. S. A. 2010, 107:17433-17438.
8. Cushman F., Young L., Hauser M. The role of conscious reasoning and intuition in moral judgment. Psychol. Sci. 2006, 17:1082-1089.
9. EMCDDA Annual Report on the State of the Drugs Problem 2010, European Monitoring Centre for Drugs and Drug Addiction, Lisbon.
10. Fernández-Serrano M.J., Lozano O., Pérez-García M., Verdejo-García A. Impact of severity of drug use on discrete emotions recognition in polysubstance abusers. Drug Alcohol Depend. 2010, 109. 57-54.
11. First M.B., Spitzer R.L., Gibbon M., Williams J.B., Benjamin L.S. Structured Clinical Interview for Axis I DSM-IV Disorders 1994, Biometrics Research, New York.
12. Foisy M.L., Philippot P., Verbanck P., Pelc I., Van der Straten G., Kornreich C. Emotional facial expression decoding impairment in persons dependent on multiple substances: impact of a history of alcohol dependence. J. Stud. Alcohol 2005, 66:637-681.
13. Franklin T.R., Acton P.A., Maldjian J.A., Gray J.D., Croft J.R., Dackis C.A., O'Brien C.P., Childress A.R. Decreased gray matter concentration in the insular, orbitofrontal, cingulate, and temporal cortices of cocaine patients. Biol. Psychiatry 2002, 51:134-142.
14. Greene J.D., Sommerville R.B., Nystrom L.E., Darley J.M., Cohen J.D. An fMRI investigation of emotional engagement in moral judgment. Science 2001, 293:2105-2108.
15. Greene J.D. Why are VMPFC patients more utilitarian? A dual-process theory of moral judgment explains. Trends Cogn. Sci. 2007, 11(8):322-323.
16. Greene J.D., Morelli S.A., Lowenberg K., Nystrom L.E., Cohen J.D. Cognitive load selectively interferes with utilitarian moral judgment. Cognition 2008, 107:1144-1154.
17. Kim Y.T., Lee J.J., Song H.J., Kim J.H., Kwon D.H., Kim M.N., Yoo D.S., Lee H.J., Kim H.J., Chang Y. Alterations in cortical activity of male methamphetamine abusers performing an empathy task: fMRI study. Hum. Psychopharmacol. 2010, 25:63-70.
18. Koenigs M., Young L., Adolphs R., Tranel D., Hauser M., Damasio A. Damage to the prefrontal cortex increases utilitarian moral judgements. Nature 2007, 447:808-911.
19. Korneich C., Foisy M.L., Philippot P., Dan B., Tecco J., Noel X., Hess U., Pelc I., Verbanck P. Impaired emotional facial expression recognition in alcoholics, opiate dependence subjects, methadone maintained subjects and mixed alcohol-opiate antecedents subjects compared with normal controls. Psychiatry Res. 2003, 119:251-260.
20. Korneich C., Philippot P., Foisy M.L., Blairy S., Raynaud E., Dan B., Hess U., Noel X., Pelc I., Verbanck P. Impaired emotional facial expression recognition is associated with interpersonal problems in alcoholism. Alcohol Alcohol. 2002, 37:390-400.
21. Leeman R.F., Toll B.A., Taylor L.A., Volpicelli J.R. Alcohol-induced disinhibition expectancies and impaired control as prospective predictors of problem drinking in undergraduates. Psychol. Addict. Behav. 2009, 23:553-563.
22. Maurage P., Grynberg D., Noël X., Joassin F., Hanak C., Verbanck V., Luminet O., Timary P., Campanella S., Philippot P. The "reading the mind in the eyes" test as a new way to explore complex emotions decoding in alcohol dependence. Psychiatry Res. 2011, 190:375-378.
23. Maurage P., Grynberg D., Noël X., Joassin F., Philippot P., Hanak C., Verbanck V., Luminet O., Timary P., Campanella S. Dissociation between affective and cognitive empathy in alcoholism: a specific deficit for the emotional dimension. Alcohol. Clin. Exp. Res. 2011, 35:1662-1668.
24. Méndez M., Anderson E., Shapira J. An investigation of moral judgments in frontotemporal dementia. Cogn. Behav. Neurol. 2005, 18:193-197.
25. Moll J., Oliveira-Souza R., Grafman J. Opinion: the neural basis of human moral cognition. Nat. Rev. Neurosci. 2005, 6:799-809.
26. Moretto G., Làdavas E., Mattioli F., Di Pellegrino G. A psychophysiological investigation of moral judgment after ventromedial prefrontal damage. J. Cogn. Neurosci. 2010, 22:1888-1899.
27. Payer D.E., Lieberman M.D., London E.D. Neural correlates of affect processing and aggression in methamphetamine dependence. Arch. Gen. Psychiatry 2011, 68:271-282.
28. Pyysiäinen I., Hauser M. The origins of religion: evolved adaptation or by-product?. Trends Cogn. Sci. 2010, 14:104-109.
29. Tanabe J., Tregellas J.R., Dalwani M., Thompson L., Owens E., Crowley T., Banich M. Medial orbitofrontal cortex gray matter is reduced in abstinent substance-dependent individuals. Biol. Psychiatry 2009, 65:160-164.
30. Uekermann J., Daum I., Schlebusch P., Trenckmann U. Processing of affective stimuli in alcoholism. Cortex 2005, 41:189-194.
31. Uekermann J., Channon S., Winkel K., Schlebusch P., Daum I. Theory of mind, humour processing and executive functioning in alcoholism. Addiction 2007, 102:232-240.
32. Verdejo-García A., Bechara A., Recknor E.C., Perez-Garcia M. Executive dysfunction in substance dependent individuals during drug use and abstinence: an examination of the behavioral, cognitive, and emotional correlates of addiction. J. Int. Neuropsychol. Soc. 2006, 12:405-415.
33. Verdejo-García A., Rivas-Pérez C., Vilar-López R., Pérez-García M. Strategic self-regulation, decision-making and emotion processing in poly-substance abusers in their first year of abstinence. Drug Alcohol Depend. 2007, 86:139-146.
34. Verdejo-García A., Lawrence A.J., Clark L. Impulsivity as a vulnerability marker for substance-use disorders: review of findings from high-risk research, problem gamblers and genetic association studies. Neurosci. Biobehav. Rev. 2008, 32:777-810.
35. Verdejo-García A., López-Torrecillas, Aguilar de Arcos F., Pérez-García M. Differential effects of MPMA, cocaine, and cannabis use severity on distinctive components of the executive functions in polysubstance users: a multiple regression analysis. Addict. Behav. 2005, 30:89-101.
36. Volkow N.D., Baler R.D., Goldstein R.Z. Addiction: pulling at the neural threads of social behaviors. Neuron 2011, 69:599-602.
37. Yechiam E., Kanz J., Bechara A., Stout J.C., Busemeyer J.R., Altmaier E.M., Paulsen J. Neurocognitive deficits related to poor decision-making in people behind bars. Psychon. Bull. Rev. 2008, 15:44-51.
38. Young L., Cushman F., Hauser M., Saxe R. The neural basis of the interaction between theory of mind and moral judgment. PNAS 2007, 104:8235-8240.