Rational synthesis design of a potent anti-diabetic therapeutic 'pioglitazone' using retrosynthetic analysis

Journal of Chemical and Pharmaceutical Research

Volumn 4, Issue 9, 2012, Pages 4323-4333

  Bhanja, Chittaranjan ^a   Jena, Satyaban ^a  

^a UTKAL UNIVERSITY   (India)

Author keywords

Antidiabetic agent; Drug synthesis; Pioglitazone; Retrosynthetic analysis; Synthon disconnection approach

Indexed keywords

ANTIDIABETIC AGENTS; DRIVING FORCES; DRUG RESEARCH; HARVARD UNIVERSITY; MAJOR FACTORS; MEDICINAL CHEMISTRY; PIOGLITAZONE; RATIONAL SYNTHESIS DESIGN; RETROSYNTHETIC ANALYSIS; SHORT REACTION TIME; SYNTHETIC ROUTES; SYNTHONS;

DESIGN;

1 BROMO 4 (2 (5 ETHYLPYRIDINE 2 YL)ETHOXY)BENZENE; 1 BROMO 4 [2 (5 ETHYLPYRIDINE 2 YL)ETHOXY]BENZENE; 1 NITRO 4 [2 (5 ETHYLPYRIDINE 2 YL)ETHOXY]BENZENE; 2 (5 ETHYL 2 PYRIDYL)ETHANOL; 2 (5 ETHYLPYRIDINE 2 YL)ETHANOL; 2 IMINOTHIAZOLIDONE; 4 [2 (5 ETHYL PYRIDIN 2 YL)ETHOXY]BENZALDEHYDE; 4 [2 (5 ETHYLPYRIDINE 2 YL)ETHOXY]BENZALDEHYDE; 4 [2 (5 ETHYLPYRIDINE 2 YL)ETHOXY]BENZONITRILE; 4 BROMOPHENOL; 4 HYDROXYBENZALDEHYDE; 5 [4 [2 (5 ETHYL 2 PYRIDYL)ETHOXY]BENZILIDENE]2,4 THIAZOLIDINEDIONE; 5 [4 [2 (5 ETHYLPYRIDINE 2 YL)ETHOXY]BENZYLIDENE]THIAZOLIDINE 2,4 DIONE; 5 ETHYL 2 METHYL PYRIDINE; PIOGLITAZONE; THIOUREA; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHEMICAL REACTION; CYCLIZATION; DIABETES MELLITUS; DRUG DESIGN; DRUG HYDROLYSIS; DRUG RESEARCH; DRUG STRUCTURE; DRUG SYNTHESIS; HYDROFORMYLATION; HYDROGENATION; HYDROGENOLYSIS; POLYMERIZATION; PROBLEM SOLVING; RETROSYNTHETIC ANALYSIS; SUBSTITUTION REACTION;

EID: 84869202656     PISSN: None     EISSN: 09757384     Source Type: Journal    
DOI: None     Document Type: Article

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