Mucor irregularis Infection and Lethal Midline Granuloma: A Case Report and Review of Published Literature

Mycopathologia

Volumn 174, Issue 5-6, 2012, Pages 429-439

  Li, Dong Ming ^a   Lun, Li De ^b  

^a PEKING UNIVERSITY THIRD HOSPITAL   (China)

^b AIR FORCE GENERAL HOSPITAL   (China)

Author keywords

Lethal midline granuloma; Mucor irregularis; Mucorales; Mycosis; NK T cell lymphoma; Rhizomucorvariabilis

Indexed keywords

MUCOR; MUCORALES;

EID: 84869196209     PISSN: 0301486X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11046-012-9559-2     Document Type: Review

References (94)

1. Friedmann I, Sando I, Balkany T. Idiopathic pleomorphic midfacial granuloma (Stewart's type). J Laryngol Otol. 1978; 92: 601-11.
2. Califano L, Zupi A, Maremonti P, De Rosa G. Sinonasal lymphoma presenting as a lethal midline granuloma: case report. J Oral Maxillofac Surg. 1998; 56: 667-71.
3. Tsokos M, Fauci AS, Costa J. Idiopathic midline destructive disease (IMDD): a subgroup of patients with the "midline granuloma" syndrome. Am J Clin Pathol. 1982; 77: 162-8.
4. Rodrigo JP, Suárez C, Rinaldo A, Devaney KO, Carbone A, Barnes L, et al. Idiopathic midline destructive disease: fact or fiction. Oral Oncol. 2005; 41: 340-8.
5. Barker TH, Hosni AA. Idiopathic midline destructive disease-does it exist? J Laryngol Otol. 1998; 112: 307-9.
6. Batra P, Shah N, Mathur S. Midline lethal granuloma-a clinical enigma. Indian J Dent Res. 2003; 14: 174-83.
7. Kohrt H, Advani R. Extranodal natural killer/T-cell lymphoma: current concepts in biology and treatment. Leuk Lymphoma. 2009; 50: 1773-84.
8. Goldberg RA, Weisman JS, McFarland JE, Krauss HR, Hepler RS, Shorr N, et al. Orbital inflammation and optic neuropathies associated with chronic sinusitis of intranasal cocaine abuse. Possible role of contiguous inflammation. Arch Ophthalmol. 1989; 107: 831-5.
9. Torre V, Bucolo S, Galletti B, Cavallari V. Midfacial granuloma syndrome or an inflammatory non-specific disease? A case report. J Oral Pathol Med. 2001; 30: 190-2.
10. Isobe Y, Aritaka N, Sasaki M, Oshimi K, Sugimoto K. Spontaneous regression of natural killer cell lymphoma. J Clin Pathol. 2009; 62: 647-50.
11. Hu ZM, Wang Y, Zhou FH, Chen LQ, Tong ZS, Jiang P, et al. Primary cutaneous mucormycosis due to Rhizomucor variabilis: a case report. Chin J Dermatol. 2010; 43: 259-62.
12. Hemashettar BM, Patil RN, O'Donnell K, Chaturvedi V, Ren P, Padhye AA, et al. Chronic rhinofacial mucormycosis caused by Mucor irregularis (Rhizomucor variabilis) in India. J Clin Microbiol. 2011; 49: 2372-5.
13. Lu XL, Liu ZH, Shen YN, She XD, Lu GX, Zhan P, et al. Primary cutaneous zygomycosis caused by Rhizomucor variabilis: a new endemic zygomycosis? A case report and review of 6 cases reported from China. Clin Infect Dis. 2009; 49: e39-43.
14. Fu M, Chen H, Song L, Chen W, Hou W, Li H, et al. Facial mucormycosis due to Rhizomucor variabilis: a case report [in Chinese]. Int J Dermatol Venereol. 2006; 32: 67-9.
15. Zhao Y, Zhang QQ, Li L, Zhu JH, Kang KF, Chen LJ, et al. Primary cutaneous mucormycosis caused by Rhizomucor variabilis in an immunocompetent patient. Mycopathologia. 2009; 168: 243-7.
16. Li DM, de Hoog GS. Rhino-orbital-cerebral mycosis and cavernous thrombosis, a case report and review of published literature. Mycopathologia. (submitted).
17. Martín-Moro JG, Calleja JMLA, García MB, Carretero JLC, Rodríguez JG. Rhinoorbitocerebral mucormycosis: a case report and literature review. Med Oral Patol Oral Cir Bucal. 2008; 13: E792-5.
18. Au WY, Ma SY, Chim CS, Choy C, Loong F, Lie AKW, et al. Clinicopathologic features and treatment outcome of mature T-cell and natural killer-cell lymphomas diagnosed according to the World Health Organization classification scheme: a single center experience of 10 years. Ann Oncol. 2005; 16: 206-14.
19. Al-Hakeem DA, Fedele S, Carlos R, Porter S. Extranodal NK/T-cell lymphoma, nasal type. Oral Oncol. 2007; 43: 4-14.
20. Zhang S, Zhou X, Zhang Y, Wang P, Zhang C, Huang SF, et al. Pathological features and types of T and NKcell lymphomas based on 152 cases. J Diag Pathol. 2006; 13: 12-4.
21. Mendenhall WM, Olivier KR, Lynch JW, Mendenhall NP. Lethal midline granuloma-nasal natural killer/T-cell lymphoma. Am J Clin Oncol. 2006; 29: 202-6.
22. Schell WA, O'Donnell K, Alspaugh JA. Heterothallic mating in Mucor irregularis and first isolate of the species outside of Asia. Med Mycol. 2011; 49: 714-23.
23. Zheng R, Chen C. A non-thermophilic Rhizomucor causing human primary cutaneous mucormycosis. Mycosystema. 1991; 4: 45-57.
24. Zhou JC, Wang L, Xu Y, Zhong BY, Hao F. A case of Rhizomucor variabilis infection in the face. Chin J Mycol. 2011; 6: 361-2.
25. Zhang SP, Hu P, Zhou HL, Jiang FX, Wu AL, Lv GX. A case of Rhizomucor variabilis infection in the face. Chin J Dermatol. 2012; 43: 134.
26. Li CL, Wu L, Hao XD, Jia TH, Guo H, Zhang QQ. Pathological and electronic investigations of cutaneous mucorales infection caused by Rhizomucor variabilis sp. Chin J Pathol. 1994; 23: 176-7.
27. Li CY, Li Y, Hu ZM. A case report of primary cutaneous mucormycosis caused by Rhizomucor variabilis [in Chinese]. J Clin Dermatol. 2004; 33: 158-9.
28. Wang AP, Li RY, Wang DL, Wang XH, Zou ZD, Wan Z. A case of necrotic mucocutaneous mucormycosis due to Rhizomucor variabilis. Chin J Dermatol. 1994; 27: 51-2.
29. Abuali MM, Posada R, Del Toro G, Roman E, Ramani R, Chaturvedi S, et al. Rhizomucor variabilis var. regularior and Hormographiella aspergillata infections in a leukemic bone marrow transplant recipient with refractory neutropenia. J Clin Microbiol. 2009; 47: 4176-9.
30. Ribeiro NFF, Heath CH, Kierath J, Rea S, Duncan-Smith M, Wood FM, et al. Burn wounds infected by contaminated water: case reports, review of the literature and recommendations for treatment. Burns. 2010; 36: 9-22.
31. Tomita H, Muroi E, Takenaka M, Nishimoto K, Kakeya H, Ohno H, et al. Rhizomucor variabilis infection in human cutaneous mucormycosis. Clin Exp Dermatol. 2010.
32. Torres JR, Torres-Viera MA, Schupbach J, Rangel HR, Pujol FH. Non-immune thrombocytopenia responsive to antiretroviral therapy and HIV-2 infection. J Infect. 2007; 54: e21-4.
33. Gold JE, Ghali V, Gold S, Brown JC, Zalusky R. Angiocentric immunoproliferative lesion/T-cell non-Hodgkin's lymphoma and the acquired immune deficiency syndrome: a case report and review of the literature. Cancer. 1990; 66: 2407-13.
34. Cobo F, Talavera P, Busquier H, Concha A. CNK/T-cell brain lymphoma associated with Epstein-Barr virus in a patient with AIDS. Neuropathology. 2007; 27: 396-402.
35. Vidal E, Deán A, Alamillos F, Salas J, López R. Lethal midline granuloma in a human immunodeficiency virus-infected patient. Am J Med. 2001; 111: 244-5.
36. Lawyer C, Henkle J, Bakir H. Nasal carriage of staphylococcal infection in Wegener granulomatosis. Ann Intern Med. 1994; 121: 74-5.
37. van Putten JW, van Haren EH, Lammers JW. Association between Wegener's granulomatosis and Staphylococcus aureus infection? Eur Respir J. 1996; 9: 1955-7.
38. Rachapalli SM, Kiely PDW. Cocaine-induced midline destructive lesions mimicking ENT-limited Wegener's granulomatosis. Scand J Rheumatol. 2008; 37: 477-80.
39. Sittel C, Eckel HE. Nasal cocaine abuse presenting as a central facial destructive granuloma. Eur Arch Otorhinolaryngol. 1998; 255: 446-7.
40. Angit C, Dabrowski MT, Owen CM. Cocaine-induced midline destructive lesion. Clin Exp Dermatol. 2009; 34: e469-70.
41. Smith JC, Kacker A, Anand VK. Midline nasal and hard palate destruction in cocaine abusers and cocaine's role in rhinologic practice. Ear Nose Throat J. 2002; 81: 172-7.
42. Sercarz JA, Strasnick B, Newman A, Dodd LG. Midline nasal destruction in cocaine abusers. Otolaryngol Head Neck Surg. 1991; 105: 694-701.
43. Chen CS, Miller NR, Lane A, Eberhart C. Third cranial nerve palsy caused by intracranial extension of a sino-orbital natural killer T-cell lymphoma. J Neuroophthalmol. 2008; 28: 31-5.
44. Liu JK, Sayama C, Chin SS, Couldwell WT. Extranodal NK/T-cell lymphoma presenting as a pituitary mass. Case report and review of the literature. J Neurosurg. 2007; 107: 660-5.
45. Roden MM, Zaoutis TE, Buchanan WL, Knudsen TA, Sarkisova TA, Schaufele RL, et al. Epidemiology and outcome of zygomycosis: a review of 929 reported cases. Clin Infect Dis. 2005; 41: 634-53.
46. Wang J, Liao Y. Spoeranox in the treatment of primary cutaneous mucormycosis: report of a case. J Clin Dermatol. 1999; 28: 174-6.
47. Ketharanathan N, van Kipshagen PJ, Vasmel W, Barbé E, de Vries N. T/NK cell lymphoma presenting as a "blocked nose". Eur Arch Otorhinolaryngol. 2008; 265: 1131-4.
48. Ostri C, Heegaard S, Prause JU. Sclerosing Wegener's granulomatosis in the orbit. Acta Ophthalmol (Copenh). 2008; 86: 917-20.
49. Ferenczi K, Summers P, Aubert P, Cooper B, Meyerson H, Cooper KD, et al. A case of CD30 + nasal natural killer/T-cell lymphoma. Am J Dermatopathol. 2008; 30: 567-71.
50. Kuo TT, Shih LY, Tsang NM. Nasal NK/T cell lymphoma in Taiwan: a clinicopathologic study of 22 cases, with analysis of histologic subtypes, Epstein-Barr virus LMP-1 gene association, and treatment modalities. Int J Surg Pathol. 2004; 12: 375-87.
51. Meyer JH, Scharf B, Gerling J. Midline granuloma presenting as orbital cellulitis. Graefes Arch Clin Exp Ophthalmol. 1996; 234: 137-9.
52. Hon C, Kwok AKH, Shek TWH, Chim JCS, Au WY. Vision-threatening complications of nasal T/NK lymphoma. Am J Ophthalmol. 2002; 134: 406-10.
53. Chim CS, Ooi GC, Shek TW, Liang R, Kwong YL. Lethal midline granuloma revisited: nasal T/Natural-killer cell lymphoma. J Clin Oncol. 1999; 17: 1322-5.
54. Baba S, Baba M, Hagisawa M, Kimura M, Nakashima M, Nakahara H, et al. A case of nasal natural killer/T lymphoma revealed by repeated deep neck abscess. Am J Otolaryngol. 2009; 30: 269-72.
55. Reinartz SM, Schot LJ, Riedl RG, Oldenburger F, van den Brekel MWM. Presentation of two cases of nasal type NK/T-cell lymphoma. Eur Arch Otorhinolaryngol. 2007; 264: 39-43.
56. Brusati R, Carota F, Mortini P, Chiapasco M, Biglioli F. A peculiar case of midface reconstruction with four free flaps in a cocaine-addicted patient. J Plast Reconstr Aesthet Surg. 2009; 62: e33-40.
57. Guttal SS, Patil NP, Shetye AD. Prosthetic rehabilitation of a midfacial defect resulting from lethal midline granuloma-a clinical report. J Oral Rehabil. 2006; 33: 863-7.
58. Ooi GC, Chim CS, Liang R, Tsang KW, Kwong YL. Nasal T-cell/natural killer cell lymphoma: CT and MR imaging features of a new clinicopathologic entity. AJR Am J Roentgenol. 2000; 174: 1141-5.
59. Poorter RL, de Bree R, Leemans CR, van der Valk P, Slotman BJ, Langendijk JA, et al. Re-irradiation of a second localization of idiopathic midline destructive disease in the head and neck area. Eur Arch Otorhinolaryngol. 2007; 264: 1521-3.
60. Zamolo G, Gruber F, Manestar D, Segon M, Kolić Z, Jonjić A, et al. Lethal midline granuloma starting as granuloma laryngis. Tumori. 2000; 86: 98-101.
61. Harabuchi Y, Takahara M, Kishibe K, Moriai S, Nagato T, Ishii H, et al. Nasal natural killer (NK)/T-cell lymphoma: clinical, histological, virological, and genetic features. Int J Clin Oncol. 2009; 14: 181-90.
62. Rasmussen N. Management of the ear, nose, and throat manifestations of Wegener granulomatosis: an otorhinolaryngologist's perspective. Curr Opin Rheumatol. 2001; 13: 3-11.
63. Berk V, Yildiz R, Akdemir UO, Akyurek N, Karabacak NI, Coskun U, et al. Disseminated extranodal NK/T-cell lymphoma, nasal type, with multiple subcutaneous nodules: utility of 18F-FDG PET in staging. Clin Nucl Med. 2008; 33: 365-6.
64. Srivastava N, Mishra N, Singh S. Erythematous indurated swelling on nose and upper lip. Cutaneous T cell lymphoma. Dermatol Online J. 2008; 14: 16.
65. Whittaker S, Foroni L, Luzzatto L, Lampert I, Amlott P, Munro A, et al. Lymphomatoid granulomatosis-evidence of a clonal T-cell origin and an association with lethal midline granuloma. Q J Med. 1988; 68: 645-55.
66. McBride P. Photographs of a case of rapid destruction of the nose and face. Otol. 1897; 12: 64-6.
67. Ahmed M, Niffenegger JH, Jakobiec FA, Ben-Arie-Weintrob Y, Gion N, Androudi S, et al. Diagnosis of limited ophthalmic Wegener granulomatosis: distinctive pathologic features with ANCA test confirmation. Int Ophthalmol. 2008; 28: 35-46.
68. Friedmann I. McBride and the midfacial granuloma syndrome. J Laryngol Otol. 2002; 116: 882-92.
69. Mehta V, Balachandran C, Bhat S, Geetha V, Fernandes D. Nasal NK/T cell lymphoma presenting as a lethal midline granuloma. Indian J Dermatol Venereol Leprol. 2008; 74: 145-7.
70. Jia H, Sun T. Extranodal NK/T-cell lymphoma mimicking cellulitis. Leuk Lymphoma. 2004; 45: 1467-70.
71. Nakajima H, Imanishi N, Aiso S. Facial artery in the upper lip and nose: anatomy and a clinical application. Plast Reconstr Surg. 2002; 109: 855-61; discussion 862.
72. Marsot-Dupuch K, Quillard J, Meyohas MC. Head and neck lesions in the immunocompromised host. Eur Radiol. 2004; 14(Suppl 3): E155-67.
73. Teng MM, Chang CY, Guo WY, Li WY, Chang T. CT evaluation of polymorphic reticulosis. Neuroradiology. 1990; 31: 498-501.
74. Ochiai H, Iseda T, Miyahara S, Goya T, Wakisaka S. Rhinocerebral mucormycosis-case report. Neurol Med Chir (Tokyo). 1993; 33: 373-6.
75. Ko YH, Ree HJ, Kim WS, Choi WH, Moon WS, Kim SW, et al. Clinicopathologic and genotypic study of extranodal nasal-type natural killer/T-cell lymphoma and natural killer precursor lymphoma among Koreans. Cancer. 2000; 89: 2106-16.
76. Brodkin DE, Hobohm DW, Nigam R. Nasal-type NK/T-cell lymphoma presenting as hemophagocytic syndrome in an 11-year-old Mexican boy. J Pediatr Hematol Oncol. 2008; 30: 938-40.
77. Li C, Xu Y, Hu Q. Facial Cutaneous Rhizomucormycosis caused by Rhizomucor variabilis: a case report [in Chinese]. Chin J Mycol. 2006; 1: 284-5.
78. Dökmetaş HS, Canbay E, Yilmaz S, Elaldi N, Topalkara A, Oztoprak I, et al. Diabetic ketoacidosis and rhino-orbital mucormycosis. Diabetes Res Clin Pract. 2002; 57: 139-42.
79. Ambrosetti D, Hofman V, Castillo L, Gari-Toussaint M, Hofman P. An expansive paranasal sinus tumour-like lesion caused by Bipolaris spicifera in an immunocompetent patient. Histopathology. 2006; 49: 660-2.
80. Marsot-Dupuch K, Cabane J, Raveau V, Aoun N, Tubiana JM. Lethal midline granuloma: impact of imaging studies on the investigation and management of destructive mid facial disease in 13 patients. Neuroradiology. 1992; 34: 155-61.
81. Drake-Lee AB, Milford CA. A review of the role of radiology in non-healing granulomas of the nose and nasal sinuses. Rhinology. 1989; 27: 231-6.
82. Borges A, Fink J, Villablanca P, Eversole R, Lufkin R. Midline destructive lesions of the sinonasal tract: simplified terminology based on histopathologic criteria. AJNR Am J Neuroradiol. 2000; 21: 331-6.
83. Flower C, Prussia P, Corbin D. Extensive extranodal adult T-cell lymphoma presenting with a lytic arthropathy of the ankle. J Clin Rheumatol. 2007; 13: 328-30.
84. Chan JK, Sin VC, Wong KF, Ng CS, Tsang WY, Chan CH, et al. Nonnasal lymphoma expressing the natural killer cell marker CD56: a clinicopathologic study of 49 cases of an uncommon aggressive neoplasm. Blood. 1997; 89: 4501-13.
85. Batsakis JG. Midfacial necrotizing diseases. Ann Otol Rhinol Laryngol. 1982; 91: 541-2.
86. Lim MS, de Leval L, Quintanilla-Martinez L. Commentary on the 2008 WHO classification of mature T- and NK-cell neoplasms. Journal of hematopathology. 2009.
87. Matsuda M, Iwanaga T, Hashimoto S, Uesugi T, Itagaki N. Primary Epstein-Barr virus-negative nasal-type natural killer/T cell lymphoma of the testis. Leuk Res. 2009; 33: e119-20.
88. Aydogdu I, Sari R, Mizrak B. Case report. Rhinocerebral zygomycosis. Mycoses. 2001; 44: 59-60.
89. Lee J, Park YH, Kim WS, Lee SS, Ryoo BY, Yang SH, et al. Extranodal nasal type NK/T-cell lymphoma: elucidating clinical prognostic factors for risk-based stratification of therapy. Eur J Cancer. 2005; 41: 1402-8.
90. Oshimi K. Progress in understanding and managing natural killer-cell malignancies. Br J Haematol. 2007; 139: 532-44.
91. Zhang XF, Ye QY, Yang XC, Deng J, Hao F, Song Q, et al. One case of nasal tye NK/T - cell lymphoma. J Clin Dermatol. 2005; 34: 752-3.
92. Shibahara T, Mitarai Y, Ishikawa Y, Sato M, Kadota K. Bovine nasal eosinophilic, granuloma with blood eosinophilia caused by Nocardia species. Aust Vet J. 2001; 79: 363-5.
93. Wang A, Li R, Wang D. Pathogenesis of Rhizomucor variabilis in mouse. J Clin Dermatol. 1996; 10(264): 272.
94. Zhao S, Tang QL, He MX, Yang F, Wang H, Zhang WY, et al. A novel nude mice model of human extranodal nasal type NK/T-cell lymphoma. Leukemia. 2008; 22: 170-8.