Nasal-type NK/T-cell lymphoma presenting as hemophagocytic syndrome in an 11-year-old mexican boy

Journal of Pediatric Hematology/Oncology

Volumn 30, Issue 12, 2008, Pages 938-940

  Brodkin, David E ^a   Hobohm, Dan W ^a   Nigam, Renuka ^a  

^a MARICOPA MEDICAL CENTER   (United States)

Author keywords

Epstein Barr virus; EUNKTL; Hemophagocytic lymphohistiocytosis; Hemophagocytic syndrome; Nasal type NK T cell lymphoma; NK T cell lymphoma; UNKTL

Indexed keywords

AMOXICILLIN; AMOXICILLIN PLUS CLAVULANIC ACID;

ANAMNESIS; ARTICLE; BONE MARROW BIOPSY; CASE REPORT; CHILD; CLINICAL FEATURE; HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS; HUMAN; LYMPH NODE BIOPSY; MALE; PRIORITY JOURNAL; SCHOOL CHILD; T CELL LYMPHOMA; DIFFERENTIAL DIAGNOSIS; FATALITY; MEXICO; MULTIPLE ORGAN FAILURE; NATURAL KILLER CELL; NOSE TUMOR; PATHOLOGY;

CHILD; DIAGNOSIS, DIFFERENTIAL; FATAL OUTCOME; HUMANS; KILLER CELLS, NATURAL; LYMPHOHISTIOCYTOSIS, HEMOPHAGOCYTIC; LYMPHOMA, T-CELL; MALE; MEXICO; MULTIPLE ORGAN FAILURE; NOSE NEOPLASMS;

EID: 59149092277     PISSN: 10774114     EISSN: 15363678     Source Type: Journal    
DOI: 10.1097/MPH.0b013e31817e4b25     Document Type: Article

References (19)

1. Siu LL, Kwong YL. Natural killer cell malignancies: clinicopatho-logic and molecular features. Histol Histopathol. 2002;17:539-554.
2. Jaffe ES. Mature T-cell and NK-cell lymphomas in the pediatric age group. Am J Clin Pathol. 2004;122:S110-S121.
3. Jaffe ES, Chan JKC, Su IJ, et al. Report of the Workshop on Nasal and Related Extranodal Angiocentic T/Natural Killer Cell Lymphomas. Definitions, differential diagnosis, and epidemiology. Am J Surg Pathol. 1996;20:103-111.
4. Harris NL, Jaffe ES, Diebold J, et al. World Health Organization classification of neoplastic diseases of the hematopoietic and lymphoid tissues: report of the clinical advisory committee meet-ing-Airlie House, Virginia, November 1997. J Clin Oncol. 1999; 17:3835-3849.
5. Chan JKC, Jaffe ES, Ralfkiaer E. Extranodal NK/T-cell lymphoma, nasal type. In: Jaffe ES, Harris NL, Stein H, et al. Pathology and Genetics, Tumours of Haematopoietic and Lymphoid Tissues. Lyon, France: IARC Press; 2001:204-207.
6. Pagano L, Gallamini A, Trape G, et al. NK/T-cell lymphomas "nasal type": an Italian multicentric retrospective survey. Ann Oncol. 2006;17:794-800.
7. Cheung MM, Chan JK, Wong KF. Natural killer cell neoplasms: a distinctive group of highly aggressive lymphomas/leukemias. Semin Hematol. 2003;40:221-232.
8. Lee J, Park YH, Kim WS, et al. Extranodal nasal type NK/T-cell lymphoma: elucidating clinical prognostic factors for risk-based stratification of therapy. Eur J Cancer. 2005;41:1402.
9. Chan JK, Sin VC, Wong KF, et al. Nonnasal lymphoma expressing the natural killer cell marker CD56: a clinicopathologic study of 49 cases of an uncommon aggressive neoplasm. Blood. 1997;89: 4501-4513.
10. Chan JK. Natural killer cell neoplasms. Anat Pathol. 1998;3:77-145.
11. Takahashi N, Miura I, Chubachi A, et al. A clinicopathological study of 20 patients with T/natural killer (NK)-cell lymphoma-associated hemophagocytic syndrome with special reference to nasal and type nasal-type NK/T-cell lymphoma. Int J Hematol. 2001;74: 303-308.
12. Ng SB, Lai KW, Murugaya S, et al. Nasal-type extranodal natural killer/T-cell lymphomas: a clinicopathologic and genotypic study of 42 cases in Singapore. Mod Pathol. 2004;17:1097-1107.
13. Lorenzen J, Liu WP, Gi GD, et al. Nasal T/NK cell lymphoma: a clinico pathologic study of 30 west Chinese patients with special reference to proliferation and apoptosis. Leuk Lymphoma. 1996; 23:593-602.
14. Kanavaros P, De Bruin PC, Briere J, et al. Epstein-Barr virus (EBV) in extranodal T-cell non-Hodgkin's lymphomas (T-NHL). Identification of nasal T-NHL as a distinct clinicopathological entity associated with EBV. Leuk Lymphoma. 1995;18:27-34.
15. Chan JK, Yip TT, Tsang WY, et al. Detection of Epstein-Barr viral RNA in malignant lymphomas of the upper aerodigestive tract. Am J Surg Pathol. 1994;18:938-946.
16. Kanavaros P, Lescs MC, Briere J, et al. Nasal T-cell lymphoma: a clinicopathologic entity associated with peculiar phenotype and with Epstein-Barr virus. Blood. 1993;81:2688-2695.
17. Arber DA, Weiss LM, Albujar PF, et al. Nasal lymphomas in Peru. High incidence of T-cell immunophenotype and Epstein-Barr virus infection. Am J Surg Pathol. 1993;17:392-399.
18. Jang KA, Choi JH, Sung KJ, et al. Primary CD56+ nasal-type T/natural killer-cell subcutaneous panniculitic lymphoma: presentation as haemophagocytic syndrome. Br J Dermatol. 1999;141: 706-709.
19. Quintanilla-Martinez L, Franklin JL, Guerrero I, et al. Histological and immunophenotypic profile of nasal NK/T cell lymphomas from Peru: high prevalence of p53 overexpression. Hum Pathol. 1999;30:849-855.