Evaluation of immunomodulatory and antitumor activity of all trans retinoic acid (ATRA) in solid tumor bearing mice

Immunopharmacology and Immunotoxicology

Volumn 35, Issue 1, 2013, Pages 110-118

  Siddikuzzaman, ^a   Berlin, Grace V M ^a  

^a KARUNYA UNIVERSITY   (India)

Author keywords

Antioxidant and antitumor activity; ATRA; Delayed type hypersensitivity (DTH); Immunomodulator

Indexed keywords

ESTERASE; GLUTATHIONE; NITRIC OXIDE; RETINOIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BAGG ALBINO MOUSE; BONE MARROW CELL; CANCER INHIBITION; CLINICAL EVALUATION; CONTROLLED STUDY; DELAYED HYPERSENSITIVITY; FOOT PAD; HEMATOLOGY; IMMUNOMODULATION; LEUKOCYTE COUNT; MALE; MELANOMA; MELANOMA CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SHEEP ERYTHROCYTE; SURVIVAL RATE; TUMOR GROWTH; TUMOR VOLUME;

ANIMALS; ANTINEOPLASTIC AGENTS; BONE MARROW CELLS; CELL LINE, TUMOR; ERYTHROCYTES; GLUTATHIONE; HYPERSENSITIVITY; IMMUNOLOGIC FACTORS; MALE; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED BALB C; NITRIC OXIDE; SHEEP; SURVIVAL RATE; TRETINOIN;

MUS; OVIS ARIES;

EID: 84869161759     PISSN: 08923973     EISSN: 15322513     Source Type: Journal    
DOI: 10.3109/08923973.2012.712137     Document Type: Article

References (37)

1. Raphael, T.J., Kuttan, G. Effect of naturally occurring triterpenoids glycyrrhizic acid, ursolic acid, oleanolic acid and nomilin on the immune system. Phytomedicine 2003, 10, 483-489.
2. Rodrigo Mora, J., Makoto, I., Ulrich, H.V. Vitamin effects on the immune system: Vitamins A and D take center stage. Nat Rev Immunol 2008, 8, 685-698.
3. Siddikuzzaman, Guruvayoorappan, C., Berlin Grace, V.M. All trans retinoic acid and cancer. Immunopharmacol Immunotoxicol 2011, 33, 241-249.
4. Lee, Y.F., Bao, B.Y., Chang, C. Modulation of the retinoic acidinduced cell apoptosis and differentiation by the human TR4 orphan nuclear receptor. Biochem Biophys Res Commun 2004, 323, 876-883.
5. Di, C., Liao, S., Adamson, D.C., Parrett, T.J., Broderick, D.K., Shi, Q., Lengauer, C., Cummins, J.M., Velculescu, V.E., Fults, D.W., McLendon, R.E., Bigner, D.D., Yan, H. Identification of OTX2 as a medulloblastoma oncogene whose product can be targeted by alltrans retinoic acid. Cancer Res 2005, 65, 919-924.
6. Kim, D.G., Jo, B.H., You, K.R., Ahn, D.S. Apoptosis induced by retinoic acid in Hep 3B cells in vitro. Cancer Lett 1996, 107, 149-159.
7. Yang, Y., Macleod, V., Miao, H.Q., Theus, A., Zhan, F., Shaughnessy, J.D. Jr, Sawyer, J., Li, J.P., Zcharia, E., Vlodavsky, I., Sanderson, R.D. Heparanase enhances syndecan-1 shedding: a novel mechanism for stimulation of tumor growth and metastasis. J Biol Chem 2007, 282, 13326-13333.
8. Yin, L., Jie, F., Yunpeng, Z., Shaoyuan, C., Xiaodong, Z., Yuanming, Y., Chengxin, F. Immunomodulatory activity of aqueous extract of Actinidia macrosperma. Asia Pac J Clin Nutr 2007, 16, 261-265.
9. Nefedova, Y., Fishman, M., Sherman, S., Wang, X., Beg, A.A., Gabrilovich, D.I. Mechanism of all-trans retinoic acid effect on tumor-associated myeloid-derived suppressor cells. Cancer Res 2007, 67, 11021-11028.
10. Talwar, G.P. (1974). Handbook of Practical Immunology. In: Talwar, G.P., Ed. New Delhi: National Book Trust, 336-339.
11. Cole, S.P. Rapid chemosensitivity testing of human lung tumor cells using the MTT assay. Cancer Chemother Pharmacol 1986, 17, 259-263.
12. Benjamin, N.R. A rapid method for estimation of the total leukocyte count. Blood 1985, 13, 677-683.
13. Drabkin, D.L., Austin, J.M. Spectrometric studies; spectrometric constants for common hemoglobin derivatives in human, dog, and rabbit blood. J Biol Chem 1932, 98, 719-733.
14. Sredni, B., Albeck, M., Kazimirsky, G., Shalit, F. The immunomodulator AS101 administered orally as a chemoprotective and radioprotective agent. Int J Immunopharmacol 1992, 14, 613-619.
15. Bancraft, J.D., Cook, H.C., Eds. (1984). Manual of Histological Techniques. Edinburgh: Churchill Publications, 176.
16. Moran, M.A., Depicre, J.W., Mannervick, B. Levels of glutathione and glutathione-S-transferase activity in rat liver. Biochim Biophys Acta 1979, 582, 67-68.
17. Green, L.C., Wagner, D.A., Glogowski, J., Skipper, P.L., Wishnok, J.S., Tannenbaum, S.R. Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids. Anal Biochem 1982, 126, 131-138.
18. Booran, G.A., Eustis, S.L., Elwell, M.R., Montgory, C.A., McKenzie, W.F., Eds. (1990). Pathology of the Fisher Rat. San Diego: Academic Press, 405-418.
19. Berlin Grace, V.M., Niranjali Devaraj, S., Radhakrishnan Pillai, M., Devaraj, H. HPV-induced carcinogenesis of the uterine cervix is associated with reduced serum ATRA level. Gynecol Oncol 2006, 103, 113-119.
20. Kale, R., Saraf, M., Juvekar, A., Tayade, P. Decreased B16F10 melanoma growth and impaired tumour vascularization in BDF1 mice with quercetin-cyclodextrin binary system. J Pharm Pharmacol 2006, 58, 1351-1358.
21. Ratajczak, H.V., Aranyi, C., Bradof, J.N., Barbera, P., Fugmann, R., Fenters, J.D., Thomas, P.T. Ethylene dibromide: evidence of systemic and immunologic toxicity without impairment of in vivo host defenses. In Vivo 1994, 8, 879-884.
22. Wilson, S.D., McCay, J.A., Butterworth, L.F., Munson, A.E., White, K.L. Jr. Correlation of suppressed natural killer cell activity with altered host resistance models in B6C3F1 mice. Toxicol Appl Pharmacol 2001, 177, 208-218.
23. Hébert, P., Pruett, S.B. Ethanol decreases natural killer cell activation but only minimally affects anatomical distribution after administration of polyinosinic:polycytidylic acid: role in resistance to B16F10 melanoma. Alcohol Clin Exp Res 2003, 27, 1622-1631.
24. Ng, S., Yoshida, K., Zelikoff, J.T. Tumor challenges in immunotoxicity testing. Methods Mol Biol 2010, 598, 143-155.
25. Picaud, S., Bardot, B., De Maeyer, E., Seif, I. Enhanced tumor development in mice lacking a functional type I interferon receptor. J Interferon Cytokine Res 2002, 22, 457-462.
26. Gupta, Y., Jain, A., Jain, P., Jain, S.K. Design and development of folate appended liposomes for enhanced delivery of 5-FU to tumor cells. J Drug Target 2007, 15, 231-240.
27. Shahabuddin, M.S., Gopal, M., Raghavan, S.C. Intercalating, cytotoxic, antitumour activity of 8-chloro and 4-morpholinopyrimido [4',5':4,5]thieno(2,3- b)quinolines. J Photochem Photobiol B 2009, 94, 13-19.
28. Samir, P., David, B., Banji, J.F., Patel, M.M., Shah, K.K. Scrutinizing the role of aqueous extract of Trapa bispinosa as an immunomodulator in experimental animals. Int J Res Pharm Sci 2010, 1, 13-19.
29. Herberman Pinsky, C.M. Polyribonucleptides for cancer therapy: summary and recommendation for further research. J Biol Response 1985, 4, 219-221.
30. Liu, X., Chan, S.Y., Ho, P.C. Comparison of the in vitro and in vivo effects of retinoids either alone or in combination with cisplatin and 5-fluorouracil on tumor development and metastasis of melanoma. Cancer Chemother Pharmacol 2008, 63, 167-174.
31. Tami, J.A., Parr, M.D., Thompson, J.S. The immune system. Am J Hosp Pharm 1986, 43, 2483-2493.
32. Girija, K., Davis, L. Immunomodulatory activity of Withania somnifera. J Ethono-pharmacol 2000, 71, 193-200.
33. Girija, K., Sunila, E.S. Immunomodulatory and anti-tumor activity of Piper longum Linn and piperine. J Ethnopharmacol 2004, 90, 339-346.
34. Price, V.E., Greenfield, R.E. Anemia in cancer. Adv Cancer Res 1958, 5, 199-290.
35. Hogland, H.C. Haematological complications of cancer chemotherapy. Semin Oncol 1982, 9, 95-102.
36. Fenninger, L.D., Mider, G.B., Eds. (1954). Advances in Cancer Research. New York: Academic Press.
37. Syed, S.B.S., Muzib, H.R.A., Geetha, A. Evaluation of oxidative stress and nitric oxide levels in patients with oral cavity cancer. Japan J Clin Oncol 2004, 34, 379-385.