Low sperm counts in genitourinary medicine clinic attendees: Results from a case - Control study

Sexually Transmitted Infections

Volumn 88, Issue 6, 2012, Pages 422-426

  Carne, Christopher A ^a   Chilcott, Sian ^a   Palmer, Christopher ^b   Green, Oliver ^a   Bridge, Simeon ^a   Walsh, Richard ^a   Gramy Mason, Anna ^a   O'Donovan, Maria ^a  

^a ADDENBROOKE S HOSPITAL   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; CASE CONTROL STUDY; CONTROLLED STUDY; GENERAL PRACTICE; HOSPITAL PERSONNEL; HUMAN; MAJOR CLINICAL STUDY; MALE; MALE INFERTILITY; NONSPECIFIC URETHRITIS; PRIORITY JOURNAL; SEMEN ABNORMALITY; SPERMATOZOON COUNT; STATISTICAL SIGNIFICANCE;

ADULT; CASE-CONTROL STUDIES; HUMANS; MALE; OLIGOSPERMIA; PREVALENCE; URETHRITIS;

EID: 84869149368     PISSN: 13684973     EISSN: 14723263     Source Type: Journal    
DOI: 10.1136/sextrans-2011-050310     Document Type: Article

References (31)

1. Williams C, Giannopoulos T, Sherriff EA. Investigation of infertility with the emphasis on laboratory testing and with reference to radiological imaging. J Clin Pathol 2003;56:261-7.
2. Hirsh A. Male subfertility. BMJ 2003;327:669-72.
3. Younglai EV, Holloway AC, Foster WG. Environmental and occupational factors affecting fertility and IVF success. Hum Reprod Update 2005;11:43-57.
4. STI Annual Data Tables. STI Table 2a. Country UK. 2009. http://www.hpa.org.uk/web/HPAWebFile/HPAweb-C/1215589013908 (accessed 13 May 2011).
5. Carey AJ, Beagley KW. Chlamydia trachomatis, a hidden epidemic: effects on female reproduction and options for treatment. Am J Reprod Immunol 2010;63:576-86.
6. Dieterle S. Urogenital infections in reproductive medicine. Andrologia 2008;40:117-19.
7. Greendale GA, Haas ST, Holbrook K, et al. The relationship of Chlamydia trachomatis infection and male infertility. Am J Public Health 1993;83 :996-1001.
8. McKay L, Clery H, Carrick-Anderson K, et al . Genital Chlamydia trachomatis infection in a subgroup of young men in the UK. Lancet 2003;361:1792.
9. Grosskurth H, Mayaud P, Mosha F, et al. Asymptomatic gonorrhoea and chlamydial infection in rural Tanzanian men. BMJ 1996;312:277.
10. Mandal D, Gillanders V. Chlamydial infection is asymptomatic in England as well as Tanzania. BMJ 1996;312:1231.
11. Comhaire FH, Mahmoud AMA, Depuydt CE, et al. Mechanisms and effects of male genital tract infection on sperm quality and fertilising potential: the andrologist's viewpoint. Hum Reprod Update 1999;5:393-8.
12. Clinical Effectiveness Group, British Association for Sexual Health and HIV. UK National Guideline on the Management of Non-gonococcal Urethritis, 2007. http://www.bashh.org/guidelines
13. Horner PJ. Should we still be testing for asymptomatic non-specific urethritis in departments of genitourinary medicine? Int J STD AIDS 2005;16:273-7.
14. Schiefer MG. Microbiology of male urethroadnexitis: diagnostic procedures and criteria for aetiological classification. Andrologia 1998;30:7-13.
15. WHO Laboratory Manual For The Examination And Processing Of Human Semen. 5th edn. 2010. http://www.who.int/reproductivehealth/publications/infertility/ 9789241547789/en/index.html
16. Cancer Research UK - Smoking statistics. 2009. http://info. cancerresearchuk.org/cancerstats/types/lung/smoking/#source9
17. Jalal H, Stephen H, Bibby DF, et al . Molecular epidemiology of genital human papillomavirus and Chlamydia trachomatis among patients attending a genitourinary medicine clinic - will vaccines protect? Int J STD AIDS 2007;18:617-21.
18. Akande V, Turner C, Horner P, et al. Impact of Chlamydia trachomatis in the reproductive setting: British fertility society guidelines for practice. Hum Fertil (Camb) 2010;13:115-25.
19. Eley A, Pacey AA, Galdiero M, et al. Can Chlamydia trachomatis directly damage your sperm? Lancet Infect Dis 2005;5:53-7.
20. Mazzoli S, Cai T, Addonisio P, et al. Chlamydia trachomatis infection is related to poor sperm quality in young prostatitis patients. Eur Urol 2010;57:708-14.
21. Mazzoli S, Cai T, Rupealta V, et al. Interleukin 8 and anti-chlamydia trachomatis mucosal IgA as urogenital immunologic markers in patients with C trachomatis prostatic infection. Eur Urol Eur Urol 2007;51:1385-93.
22. Nunez-Calonge R, Cabellero P, Redondo C, et al. Ureaplasma urealyticum reduces motility and induces membrane alterations in human spermatozoa. Hum Reprod 1998;13:2756-61.
23. Reichart M, Kahane I, Bartoov B. In vivo and in vitro impairment of human and ram sperm nuclear chromatin integrity by sexually transmitted Ureaplasma urealyticum infection. Biol Reprod 2000;63:1041-8.
24. Taylor-Robinson D, Horner PJ. The role of Mycoplasma genitalium in non-gonococcal urethritis. Sex Transm Infect 2001;77:229-31.
25. Svenstrup HF, Fedder J, Abraham-Peskir J, et al. Mycoplasma genitalium attaches to human spermatozoa. Hum Rep 2003;18:2103-9.
26. Ness RB, Markovic N, Carlson CL, et al . Do men become infertile after having sexually transmitted urethritis? An epidemiologic examination. Fertil Steril 1997;68 :205-13.
27. Soper D. Trichomoniasis: under control or undercontrolled? Am J Obstet Gynecol 2004;190:281-90.
28. Falk L, Fredlund H, Jensen JS. Symptomatic urethritis is more prevalent in men infected with Mycoplasma genitalium than with Chlamydia trachomatis. Sex Transm Infect 2004;80:289-93.
29. Schlegel PN, Chang TS, Marshall FF. Antibiotics: potential hazards to male fertility. Fertile Steril 1991;55:235-42.
30. Hargreaves CA, Rogers S, Hills F, et al . Effects of co-trimoxazole, erythromycin, amoxycillin, tetracycline and chloroquine on sperm function in vitro. Hum Reprod 1998;13:1878-86.
31. Baker HW, Straffon WG, McGowan MP, et al. A controlled trial of the use of erythromycin for men with asthenospermia. Int J Androl 1984;7:383-8.