Islet cell transplantation: Current status in the UK

Practical Diabetes

Volumn 29, Issue 7, 2012, Pages 280-285

  Choudhary, Pratik ^a   Parrott, Neil R ^b   Birtles, Linda ^b   Rutter, Martin K ^b  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b MANCHESTER ROYAL INFIRMARY   (United Kingdom)

Author keywords

Islet cell transplantation; Pancreas transplantation; Type 1 diabetes

Indexed keywords

INSULIN;

ARTICLE; BLOOD GLUCOSE MONITORING; CONTINUOUS GLUCOSE MONITORING; HUMAN; HYPOGLYCEMIA; INSULIN DEPENDENT DIABETES MELLITUS; PANCREAS ISLET TRANSPLANTATION; SURVIVAL RATE; TREATMENT OUTCOME; UNITED KINGDOM;

EID: 84869133624     PISSN: None     EISSN: 20472900     Source Type: Journal    
DOI: 10.1002/pdi.1707     Document Type: Article

References (29)

1. Shapiro AM, et al. Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N Engl J Med 2000;343(4):230-8.
2. NICE. Allogenic pancreatic islet cell transplantation for type 1 diabetes mellitus, 2008.
3. Cryer PE. Hypoglycemia is the limiting factor in the management of diabetes. Diabetes Metab Res Rev 1999;15(1):42-6.
4. Choudhary P, et al. Frequency of biochemical hypoglycaemia in adults with type 1 diabetes with and without impaired awareness of hypoglycaemia: no identifiable differences using continuous glucose monitoring. Diabet Med 2010;27(6):666-72.
5. Geddes J, et al. Prevalence of impaired awareness of hypoglycaemia in adults with type 1 diabetes. Diabet Med 2008;25(4):501-4.
6. Donnelly LA, et al. Frequency and predictors of hypoglycaemia in type 1 and insulin-treated type 2 diabetes: a population-based study. Diabet Med 2005;22(6):749-55.
7. Gill GV, et al. Cardiac arrhythmia and nocturnal hypoglycaemia in type 1 diabetes - the 'dead in bed' syndrome revisited. Diabetologia 2009;52(1):42-5.
8. Rogers HA, et al. Patient experience of hypoglycaemia unawareness in type 1 diabetes: are patients appropriately concerned? Diabet Med 2012;29(3):321-7.
9. Ryan EA, et al. Assessment of the severity of hypoglycemia and glycemic lability in type 1 diabetic subjects undergoing islet transplantation. Diabetes 2004;53(4):955-62.
10. Gold AE, et al. Frequency of severe hypoglycemia in patients with type I diabetes with impaired awareness of hypoglycemia. Diabetes Care 1994;17(7):697-703.
11. Kovatchev BP, et al. Assessment of risk for severe hypoglycemia among adults with IDDM: validation of the low blood glucose index. Diabetes Care 1998;21(11):1870-5.
12. Hopkins D, et al. DAFNE (Dose Adjustment For Normal Eating) training delivered in routine clinical practice is associated with significant improvements in measure of quality of life and psychological distress. Diabet Med 2008;25(Suppl 1):A47.
13. NICE. Diabetes insulin pump therapy, 2008. www.nice.org.uk/TA151.
14. Pickup JC, Sutton AJ. Severe hypoglycaemia and glycaemic control in type 1 diabetes: meta-analysis of multiple daily insulin injections compared with continuous subcutaneous insulin infusion. Diabet Med 2008;25(7):765-74.
15. Garg S, et al. Reduction in duration of hypoglycemia by automatic suspension of insulin delivery: the in-clinic ASPIRE study. Diabetes Technol Ther 2012;14(3):205-9.
16. Choudhary P, et al. Insulin pump therapy with automated insulin suspension in response to hypoglycemia: reduction in nocturnal hypoglycemia in those at greatest risk. Diabetes Care 2011;34(9):2023-5.
17. Ly TT, et al. Improving epinephrine responses in hypoglycemia unawareness with real-time continuous glucose monitoring in adolescents with type 1 diabetes. Diabetes Care 2011;34(1):50-2.
18. CITR. Seventh Annual Report of the Collaborative Islet Transplant Registry. 2010. https://web.emmes. com/study/isl/reports/01062012-Scientific- Summary-7thAnnualRep.pdf.
19. Bassi R, Fiorina P. Impact of islet transplantation on diabetes complications and quality of life. Curr Diab Rep 2011;11(5):355-63.
20. Johnson JA, et al. Reduced fear of hypoglycemia in successful islet transplantation. Diabetes Care 2004;27(2):624-5.
21. Thompson DM, et al. Reduced progression of diabetic microvascular complications with islet cell transplantation compared with intensive medical therapy. Transplantation 2011;91(3):373-8.
22. Brooks A M S A, et al. Resolution of hypoglycaemia, improvement in glycaemic control and assessment of metabolic graft function in islet transplant recipients in the UK islet transplant consortium programme. Diabet Med 2012;29(Suppl 1):A15.
23. Engels EA, et al. Spectrum of cancer risk among US solid organ transplant recipients. JAMA 2011;306(17):1891-901.
24. Gruessner AC, Sutherland DE. Pancreas transplant outcomes for United States (US) cases as reported to the United Network for Organ Sharing (UNOS) and the International Pancreas Transplant Registry (IPTR). Clin Transpl 2008:45-56.
25. Sutherland DE, Gruessner AC. Long-term results after pancreas transplantation. Transplant Proc 2007;39(7):2323-5.
26. Gruessner AC, et al. Long-term outcome after pancreas transplantation. Curr Opin Transplant 2012;17(1):100-5.
27. Vivot K, et al. Instant blood-mediated inflammatory reaction during islet transplantation: the role of Tolllike receptors signaling pathways. Transplant Proc 2011;43(9):3192-4.
28. Korsgren O, Nilsson B. Improving islet transplantation: a road map for a widespread application for the cure of persons with type I diabetes. Curr Opin Transplant 2009;14(6):683-7.
29. Valdes-Gonzalez R, et al. No evidence of porcine endogenous retrovirus in patients with type 1 diabetes after long-term porcine islet xenotransplantation. J Med Virol 2010;82(2):331-4.