Searching the Clinical Fitness Landscape

PLoS ONE

Volumn 7, Issue 11, 2012, Pages

  Eppstein, Margaret J ^a   Horbar, Jeffrey D ^b,c   Buzas, Jeffrey S ^a,c   Kauffman, Stuart A ^a  

^a University of Vermont ^*  (United States)

^b UNIVERSITY OF VERMONT   (United States)

^c VERMONT OXFORD NETWORK   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CLINICAL EFFECTIVENESS; CLINICAL FITNESS LANDSCAPE; CLINICAL PATHWAY; CLINICAL PRACTICE; EVIDENCE BASED MEDICINE; HEALTH CARE QUALITY; HEALTH STATUS; INFORMATION DISSEMINATION; LEARNING ALGORITHM; MEDICAL CARE; MEDICAL PRACTICE; ORGANIZATIONAL THEORY; OUTCOME ASSESSMENT; PRACTICE GUIDELINE; PUBLIC-PRIVATE PARTNERSHIP; RISK ASSESSMENT; SAFETY; SAMPLE SIZE; SENSITIVITY ANALYSIS; STUDY DESIGN; THEORETICAL MODEL; TOTAL QUALITY MANAGEMENT;

COMPUTER SIMULATION; CONTROLLED CLINICAL TRIALS AS TOPIC; COOPERATIVE BEHAVIOR; HUMANS; INFORMATION DISSEMINATION; MODELS, THEORETICAL; PHYSICIAN'S PRACTICE PATTERNS; QUALITY IMPROVEMENT;

EID: 84869122165     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0049901     Document Type: Article

References (55)

1. Wright S, (1932) The Roles of Mutation, Inbreeding, Crossbreeding and Selection in Evolution. Proceedings of the Sixth International Congress of Genetics 1: 356-366.
2. Bateson W (1909) Heredity and Variation in Modern Lights. In: Seward AC, editor. Darwin and Modern Science. Cambridge, UK: Cambridge University Press, pp. 85-101.
3. Moore JH, (2003) The ubiquitous nature of epistasis in determining susceptibility to common human diseases. Human Heredity 56: 73-82.
4. Kauffman S, Levin S, (1987) Towards a General Theory of Adaptive Walks on Rugged Landscapes. JTB 128: 11-45.
5. Kauffman SA (1993) The Origins of Order: Self organization and selection in evolution. New York: Oxford University Press. 734 p.
6. Altenberg L (1996) NK Fitness Landscapes. In: Back T, Fogel D, Michalewicz, Z, editors. The Handbook of Evolutionary Computation. New York: Oxford University Press. Section B2.7.2, 11p.
7. Merz P (2012) Memetic Algorithms and Fitness Landscapes in Combinatorial Optimization. In: Neri F, Cotta C, Moscato P, editors. Handbook of Memetic Algorithms. Studies in Computational Intelligence 379. Berlin: Springer, pp. 95-119.
8. Whitley D, Chen W (2012) Constant Time Steepest Ascent Local Search with Statistical Lookahead for NK-Landscapes and MAX-kSAT. Proceedings of the 2012 Genetic and Evolutionary Computation Conference. New York: ACM pp. 1357-1364.
9. Auerswald P, Kauffman S, Lobo J, Shell K, (2000) The Production Recipes Approach to Modeling Technological Innovation: An Application to Learning by Doing. J Econ Dyn Control 24: 389-450.
10. Kauffman S, Lobo J, Macready WG, (2000) Optimal Search on a Technology Landscape. J Econ Behav Organ 43: 141-166.
11. Rivkin JW, Siggelkow N, (2002) Organizational Sticking Points on NK Landscapes. Complexity 7: 31-43.
12. Frenken K, (2006) A Fitness Landscape Approach to Technological Complexity, Modularity, and Vertical Disintegration. Structural Change and Economic Dynamics 17: 288-305.
13. Axelrod R, Cohen MD (1999) Harnessing Complexity: Organizational Implications of a Scientific Frontier. New York: The Free Press. 184 p.
14. Plsek P (2001) Redesigning Health Care with Insights from the Science of Complex Adaptive Systems. In: Institute of Medicine Committee on Quality of Health Care in America. Crossing the Quality Chasm: A New Health System for the 21st Century. Washington, DC: The National Academies Press. Appendix B, pp. 309-322.
15. Bar-Yam Y (2005) Making Things Work: Solving Problems in a Complex World. Cambridge, MA: NECSI Knowledge Press. 306 p.
16. Berwick DM, (1998) Developing and Testing Changes in Delivery of Care. Ann Intern Med 128: 651-656.
17. Wennberg JE, Gittelsohn A, (1973) Small Area Variations in Health Care Delivery: A population-based health information system can guide planning and regulatory decision-making. Science 182: 1102-1108.
18. McPherson K, Wennberg JE, Hovind OB, Clifford P, (1982) Small-Area Variations in the Use of Common Surgical Procedures: An International Comparison of New England, England, and Norway. N Engl J Med 307: 1310-1314.
19. Wennberg JE (2010) Tracking Medicine: A Researcher's Quest to Understand Health Care. New York: Oxford University Press. 344 p.
20. Institute of Medicine Committee on Quality of Health Care in America (2001) Crossing the Quality Chasm: A New Health System for the 21st Century. Washington, DC: The National Academies Press. 360 p.
21. Rothwell PM, (2005) External Validity of Randomised Controlled Trials: "To whom do the results of this trial apply?". Lancet 365: 82-93.
22. Dekkers OM, von Elm E, Algra A, Romijn JA, Vandenbroucke JP, (2010) How to assess the external validity of therapeutic trials: a conceptual approach. Int J Epidemiol 39: 89-94.
23. Treweek A, Zwarenstein M, (2009) Making trials matter: pragmatic and explanatory trials and the problem of applicability. Trials 10: 37.
24. Shekelle PG, Pronovost PJ, Wachter RM, Taylor SL, Dy SM, et al. (2011) Advancing the science of patient safety. Ann Intern Med 154: 693-696.
25. Pawson R, Tilley N (2004) Realistic Evaluation. London: Sage Publications. 256 p.
26. Batalden PB, Davidoff F, (2007) What is "quality improvement" and how can it transform healthcare? Qual Saf Health Care 16: 2-3.
27. Ioannidis JPA, (2005) Why most published research findings are false. PLoS Med 2: e124.
28. Berwick DM, (2008) The Science of Improvement. JAMA 299: 1182-1184.
29. Berwick DM, (2005) Broadening the view of evidence-based Medicine. Qual Saf Health Care Care 14: 315-316.
30. O'Connor GT, Plume SK, Olmstead EM, Morton JR, Maloney DT, et al. (1996) A regional intervention to improve the hospital mortality associated with coronary artery bypass graft surgery. The Northern New England Cardiovascular Disease Study Group. JAMA 275: 841-846.
31. Horbar JD, Rogowski J, Plsek PE, Delmore P, Edwards WH, et al. (2001) Collaborative Quality Improvement for Neonatal Intensive Care. Pediatrics 107: 14-22.
32. Schouten LMT, Marlies EJL, Hulscher MEJL, van Everdingen JJE, Huijsman R, et al. (2008) Evidence for the impact of quality improvement collaboratives: systematic review. BMJ 336: 1491.
33. Taylor SL, Dy S, Foy R, Hempel S, McDonald KM, et al. (2012) What context features might be important determinants of the effectiveness of patient safety practice interventions? BMJ Qual Saf 2012 doi:10.1136/bmjqs.2010.049879.
34. Kaplan HC, Provost LP, Froehle CM, Margolis PA, (2012) The Model for Understanding Success in Quality (MUSIQ): building a theory of context in healthcare quality improvement. BMJ Qual Saf 21: 13-20.
35. McLaughlin CP, Kaluzny AD, editors (2006) Continuous Quality Improvement in Health Care: Theory, Implementation, and Applications. Third Edition. Sudbury: Jones & Bartlett Learning. 678 p.
36. Newton PJ, Davidson PM, Halcomb EJ, Denniss AR, (2007) Barriers and Facilitators to the Implementation of the Collaborative Method: Reflections from a Single Site. Qual Saf Health Care 16: 409-414.
37. Schouten LMT, Grol RPTM, Hulscher MEJL, (2010) Factors Influencing Success in Quality-Improvement Collaboratives: Development and Psychometric Testing of an Instrument. Implementation Science 5: 84 9.
38. Vos L, Dückers MLA, Wagner C, van Merode GG, (2010) Applying the Quality Improvement Collaborative Method to Process Redesign: a Multiple Case Study. Implementation Science 5: 19 19.
39. Auerbach AD, Landefeld CS, Shojania KG, (2007) The tension between needing to improve and knowing how to do it. N Engl J Med 357: 608-613.
40. Hosmer D, Lemeshow S (2000) Applied Logistic Regression, 2nd Edition. New York: John Wiley & Sons, Inc. 392 p.
41. Plsek PE, (1997) Collaborating Across Organizational Boundaries to Improve the Quality of Care. Am J Infect Control 25: 85-95.
42. Plsek PE, (1999) Quality Improvement Methods in Clinical Medicine. Pediatrics 103: 203-214.
43. Rodrigues AD, editor (2008) Drug-drug Interactions. New York: Informa Healthcare. 745 p.
44. Johnell K, Klarin I, (2007) The Relationship Between Number of Drugs and Potential Drug-Drug Interactions in the Elderly: A Study of Over 600000 Elderly Patients from the Swedish Prescribed Drug Register. Drug Safety 30: 911-918.
45. Ferlie EB, Shortell SM, (2001) Improving the Quality of Health Care in the United Kingdom and the United States: A Framework for Change. Milbank Q 79: 281-315.
46. Briggs A, (2010) Transportability of Comparative Effectiveness and Cost-Effectiveness between Countries. Value Health 13: S22-S25.
47. Dechartres A, Boutron I, Trinquart L, Charles P, Ravaud P, (2011) Single-Center Trials Show Larger Treatment Effects than Multicenter trials: Evidence from a Meta-epidemiologic Study. Ann Intern Med 155: 1-39.
48. Bafeta A, Dechartres A, Trinquart L, Yavchitz A, Boutron I, et al. (2012) Impact of Single Centre Status on Estimates of Intervention Effects in Trials with Continuous Outcomes: Meta-Epidemiological Study. BMJ 344: e813 doi:10.1136/bmj.e813, 9 p.
49. Gray RJ, (1994) A Bayesian Analysis of Institutional Effects in a Multicenter Cancer Clinical Trial. Biometrics 50: 244-253.
50. Horwitz RI, Singer BH, Makuch RW, Viscoli CM, (1996) Can Treatment that is Helpful on Average be Harmful to Some Patients? A Study of the Conflicting Information Needs of Clinical Inquiry and Drug Regulation. J Clin Epidemiol 49: 395-400.
51. Freiman JA, Chalmers TC, Smith H, Kuebler RR, (1978) The Importance of Beta, the Type II Error and Sample Size in the Design and Interpretation of the Randomized Control Trial - Survey of 71 Negative Trials. N Engl J Med 299: 690-694.
52. Moher D, Dulberg CS, Wells GA, (1994) Statistical power, sample size, and their reporting in randomized controlled trials. JAMA 272: 122-124.
53. Charles P, Giraudeau B, Dechartres A, Baron G, Ravaud P, (2009) Reporting of sample size calculation in randomized controlled trials: review. BMJ 338: b1732.
54. Halpern SD, (2005) Adding nails to the coffin of underpowered trials. J Rheumatol 32: 2065-2066.
55. Kent DM, Trikalinos TA, (2009) Therapeutic Innovations, Diminishing Returns, and Control Rate Preservation. JAMA 302: 2254-2256.