메뉴 건너뛰기




Volumn 142, Issue 11, 2012, Pages 2050-2056

Early life iron deficiency impairs spatial cognition in neonatal piglets

Author keywords

[No Author keywords available]

Indexed keywords

HEMOGLOBIN; IRON; TRANSFERRIN RECEPTOR;

EID: 84869121628     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.3945/jn.112.165522     Document Type: Article
Times cited : (68)

References (58)
  • 1
    • 65449184945 scopus 로고    scopus 로고
    • Worldwide prevalence of anaemia, WHO Vitamin and Mineral Nutrition Information System 1993-2005
    • McLean E, Cogswell M, Egli I, Wojdyla D, de Benoist B. Worldwide prevalence of anaemia, WHO Vitamin and Mineral Nutrition Information System, 1993-2005. Public Health Nutr. 2009;12:444-54.
    • (2009) Public Health Nutr , vol.12 , pp. 444-454
    • McLean, E.1    Cogswell, M.2    Egli, I.3    Wojdyla, D.4    de Benoist, B.5
  • 2
    • 0034058648 scopus 로고    scopus 로고
    • Anemia and iron deficiency: effects on pregnancy outcome
    • Allen LH. Anemia and iron deficiency: effects on pregnancy outcome. Am J Clin Nutr. 2000; 71 Suppl 5:S1280-4.
    • (2000) Am J Clin Nutr , vol.71 , Issue.SUPPL. 5
    • Allen, L.H.1
  • 3
    • 0036432266 scopus 로고    scopus 로고
    • Perinatal aspects of iron metabolism
    • Rao R, Georgieff M. Perinatal aspects of iron metabolism. Acta Paediatr Suppl. 2002;91: s438:124-9.
    • (2002) Acta Paediatr Suppl , vol.91 , Issue.438 S , pp. 124-129
    • Rao, R.1    Georgieff, M.2
  • 4
    • 33745502924 scopus 로고    scopus 로고
    • Longlasting neural and behavioral effects of iron deficiency in infancy
    • discussion S72-91
    • Lozoff B, Beard J, Connor J, Barbara F, Georgieff M, Schallert T. Longlasting neural and behavioral effects of iron deficiency in infancy. Nutr Rev. 2006;64:S34-43; discussion S72-91.
    • (2006) Nutr Rev , vol.64
    • Lozoff, B.1    Beard, J.2    Connor, J.3    Barbara, F.4    Georgieff, M.5    Schallert, T.6
  • 7
    • 79951557873 scopus 로고    scopus 로고
    • National, regional, and global trends in systolic blood pressure since 1980 systematic analysis of health examination surveys and epidemiological studies with 786 country-years and 5.4 million participants
    • Danaei G, Finucane MM, Lin JK, Singh GM, Paciorek CJ, CowanMJ, Farzadfar F, Stevens GA, Lim SS, Riley LM, et al. National, regional, and global trends in systolic blood pressure since 1980: systematic analysis of health examination surveys and epidemiological studies with 786 country-years and 5.4 million participants. Lancet. 2011; 377:568-77.
    • (2011) Lancet , vol.377 , pp. 568-577
    • Danaei, G.1    Finucane, M.M.2    Lin, J.K.3    Singh, G.M.4    Paciorek, C.J.5    Cowan, M.J.6    Farzadfar, F.7    Stevens, G.A.8    Lim, S.S.9    Riley, L.M.10
  • 9
    • 33646861399 scopus 로고    scopus 로고
    • Early nutrition and its later consequences: new opportunities
    • Koletzko B. Early nutrition and its later consequences: new opportunities. Adv Exp Med Biol. 2005;569:1-12.
    • (2005) Adv Exp Med Biol , vol.569 , pp. 1-12
    • Koletzko, B.1
  • 12
    • 79957950119 scopus 로고    scopus 로고
    • Fetal and neonatal iron deficiency causes volume loss and alters the neurochemical profile of the adult rat hippocampus
    • Rao R, Tkac I, Schmidt AT, Georgieff MK. Fetal and neonatal iron deficiency causes volume loss and alters the neurochemical profile of the adult rat hippocampus. Nutr Neurosci. 2011;14:59-65.
    • (2011) Nutr Neurosci , vol.14 , pp. 59-65
    • Rao, R.1    Tkac, I.2    Schmidt, A.T.3    Georgieff, M.K.4
  • 13
    • 77955097786 scopus 로고    scopus 로고
    • Gestational and neonatal iron deficiency alters apical dendrite structure of CA1 pyramidal neurons in adult rat hippocampus
    • Brunette KE, Tran PV, Wobken JD, Carlson ES, Georgieff MK. Gestational and neonatal iron deficiency alters apical dendrite structure of CA1 pyramidal neurons in adult rat hippocampus. Dev Neurosci. 2010;32:238-48.
    • (2010) Dev Neurosci , vol.32 , pp. 238-248
    • Brunette, K.E.1    Tran, P.V.2    Wobken, J.D.3    Carlson, E.S.4    Georgieff, M.K.5
  • 14
    • 0032912252 scopus 로고    scopus 로고
    • Stress and hippocampal plasticity
    • McEwen BS. Stress and hippocampal plasticity. Annu Rev Neurosci. 1999;22:105-22.
    • (1999) Annu Rev Neurosci , vol.22 , pp. 105-122
    • McEwen, B.S.1
  • 17
  • 18
    • 0025745242 scopus 로고
    • Long-term developmental outcome of infants with iron deficiency
    • Lozoff B, Jimenez E, Wolf AW. Long-term developmental outcome of infants with iron deficiency. N Engl J Med. 1991;325:687-94.
    • (1991) N Engl J Med , vol.325 , pp. 687-694
    • Lozoff, B.1    Jimenez, E.2    Wolf, A.W.3
  • 19
    • 80155160039 scopus 로고    scopus 로고
    • Long-term brain and behavioral consequences of early iron deficiency
    • Georgieff MK. Long-term brain and behavioral consequences of early iron deficiency. Nutr Rev. 2011;69 Suppl 1:S43-8.
    • (2011) Nutr Rev , vol.69 , Issue.SUPPL. 1
    • Georgieff, M.K.1
  • 20
    • 33846006174 scopus 로고    scopus 로고
    • Early iron deficiency alters sensorimotor development and brain monoamines in rats
    • Unger EL, Paul T, Murray-Kolb LE, Felt B, Jones BC, Beard JL. Early iron deficiency alters sensorimotor development and brain monoamines in rats. J Nutr. 2007;137:118-24.
    • (2007) J Nutr , vol.137 , pp. 118-124
    • Unger, E.L.1    Paul, T.2    Murray-Kolb, L.E.3    Felt, B.4    Jones, B.C.5    Beard, J.L.6
  • 22
    • 57349165847 scopus 로고    scopus 로고
    • Early-life iron deficiency anemia alters neurotrophic factor expression and hippocampal neuron differentiation in male rats
    • Tran PV, Carlson ES, Fretham SJ, Georgieff MK. Early-life iron deficiency anemia alters neurotrophic factor expression and hippocampal neuron differentiation in male rats. J Nutr. 2008;138:2495-501.
    • (2008) J Nutr , vol.138 , pp. 2495-2501
    • Tran, P.V.1    Carlson, E.S.2    Fretham, S.J.3    Georgieff, M.K.4
  • 23
    • 69049085562 scopus 로고    scopus 로고
    • Long-term reduction of hippocampal brain-derived neurotrophic factor activity after fetalneonatal iron deficiency in adult rats
    • Tran PV, Fretham SJ, Carlson ES, Georgieff MK. Long-term reduction of hippocampal brain-derived neurotrophic factor activity after fetalneonatal iron deficiency in adult rats. Pediatr Res. 2009;65:493-8.
    • (2009) Pediatr Res , vol.65 , pp. 493-498
    • Tran, P.V.1    Fretham, S.J.2    Carlson, E.S.3    Georgieff, M.K.4
  • 24
    • 39149105277 scopus 로고    scopus 로고
    • Effect of perinatal iron deficiency on myelination and associated behaviors in rat pups. Behav
    • Wu LL, Zhang L, Shao J, Qin YF, Yang RW, Zhao ZY. Effect of perinatal iron deficiency on myelination and associated behaviors in rat pups. Behav Brain Res. 2008;188:263-70.
    • (2008) Brain Res , vol.188 , pp. 263-270
    • Wu, L.L.1    Zhang, L.2    Shao, J.3    Qin, Y.F.4    Yang, R.W.5    Zhao, Z.Y.6
  • 25
    • 0344395069 scopus 로고    scopus 로고
    • Pre- and postweaning iron deficiency alters myelination in Sprague-Dawley rats
    • Beard JL, Wiesinger JA, Connor JR. Pre- and postweaning iron deficiency alters myelination in Sprague-Dawley rats. Dev Neurosci. 2003;25:308-15.
    • (2003) Dev Neurosci , vol.25 , pp. 308-315
    • Beard, J.L.1    Wiesinger, J.A.2    Connor, J.R.3
  • 27
    • 0013966213 scopus 로고
    • Some peculiarities of cerebellar growth in pigs
    • Dickerson JW, Dobbing J. Some peculiarities of cerebellar growth in pigs. Proc R Soc Med. 1966;59:1088.
    • (1966) Proc R Soc Med , vol.59 , pp. 1088
    • Dickerson, J.W.1    Dobbing, J.2
  • 28
    • 0032432603 scopus 로고    scopus 로고
    • Age-dependent material properties of the porcine cerebrum: effect on pediatric inertial head injury criteria
    • Thibault KL, Margulies SS. Age-dependent material properties of the porcine cerebrum: effect on pediatric inertial head injury criteria. J Biomech. 1998;31:1119-26.
    • (1998) J Biomech , vol.31 , pp. 1119-1126
    • Thibault, K.L.1    Margulies, S.S.2
  • 29
    • 0018372689 scopus 로고
    • Comparative aspects of the brain growth spurt
    • Dobbing J, Sands J. Comparative aspects of the brain growth spurt. Early Hum Dev. 1979;3:79-83
    • (1979) Early Hum Dev , vol.3 , pp. 79-83
    • Dobbing, J.1    Sands, J.2
  • 32
    • 0023081945 scopus 로고
    • The pig as a model for human nutrition
    • Miller ER, Ullrey DE. The pig as a model for human nutrition. Annu Rev Nutr. 1987;7:361-82.
    • (1987) Annu Rev Nutr , vol.7 , pp. 361-382
    • Miller, E.R.1    Ullrey, D.E.2
  • 33
    • 84869104569 scopus 로고    scopus 로고
    • Nutrition SoS, Nutrition CoA, Council N.R., Washington DC: The National Academies Press;
    • Nutrition SoS, Nutrition CoA, Council NR. Nutrient requirements of swine: 10th rev. ed. Washington, DC: The National Academies Press; 1998.
    • (1998) Nutrient requirements of swine: 10th rev. ed.
  • 34
    • 77956514960 scopus 로고    scopus 로고
    • Behavioral assessment of cognitive function using a translational neonatal piglet model
    • Dilger RN, Johnson RW. Behavioral assessment of cognitive function using a translational neonatal piglet model. Brain Behav Immun. 2010;24:1156-65.
    • (2010) Brain Behav Immun , vol.24 , pp. 1156-1165
    • Dilger, R.N.1    Johnson, R.W.2
  • 35
    • 84862626426 scopus 로고    scopus 로고
    • Place and direction learning in a spatial T-maze task by neonatal piglets
    • Elmore MR, Dilger R, Johnson R. Place and direction learning in a spatial T-maze task by neonatal piglets. Anim Cogn. 2012;15:667-76.
    • (2012) Anim Cogn , vol.15 , pp. 667-676
    • Elmore, M.R.1    Dilger, R.2    Johnson, R.3
  • 36
    • 0030972248 scopus 로고    scopus 로고
    • Small intestinal disaccharidase activity and ileal villus height are increased in piglets consuming formula containing recombinant human insulin-like growth factor-I
    • Houle VM, Schroeder EA, Odle J, Donovan SM. Small intestinal disaccharidase activity and ileal villus height are increased in piglets consuming formula containing recombinant human insulin-like growth factor-I. Pediatr Res. 1997;42:78-86.
    • (1997) Pediatr Res , vol.42 , pp. 78-86
    • Houle, V.M.1    Schroeder, E.A.2    Odle, J.3    Donovan, S.M.4
  • 37
    • 25444474157 scopus 로고    scopus 로고
    • The effects of hippocampal lesions on response, direction, and place learning in rats
    • Stringer KG, Martin GM, Skinner DM. The effects of hippocampal lesions on response, direction, and place learning in rats. Behav Neurosci 2005;119:946-52.
    • (2005) Behav Neurosci , vol.119 , pp. 946-952
    • Stringer, K.G.1    Martin, G.M.2    Skinner, D.M.3
  • 38
    • 57149122575 scopus 로고    scopus 로고
    • Selective lesion of septal cholinergic neurons in rats impairs acquisition of a delayed matching to position T-maze task by delaying the shift from a response to a place strategy
    • Fitz NF, Gibbs RB, Johnson DA. Selective lesion of septal cholinergic neurons in rats impairs acquisition of a delayed matching to position T-maze task by delaying the shift from a response to a place strategy. Brain Res Bull. 2008;77:356-60.
    • (2008) Brain Res Bull , vol.77 , pp. 356-360
    • Fitz, N.F.1    Gibbs, R.B.2    Johnson, D.A.3
  • 39
    • 84867990175 scopus 로고    scopus 로고
    • Brain growth of the domestic pig (Sus scrofa) from 2 to 24 weeks of age: a longitudinal study
    • Jul 6
    • Conrad MS, Dilger RN, Johnson RW. Brain growth of the domestic pig (Sus scrofa) from 2 to 24 weeks of age: a longitudinal study. Dev Neurosci. Epub 2012 Jul 6.
    • (2012) Dev Neurosci. Epub
    • Conrad, M.S.1    Dilger, R.N.2    Johnson, R.W.3
  • 40
    • 18344381289 scopus 로고    scopus 로고
    • alpha-Tocopherol and selenium facilitate recovery from lipopolysaccharideinduced sickness in aged mice
    • Berg BM, Godbout JP, Chen J, Kelley KW, Johnson RW. alpha-Tocopherol and selenium facilitate recovery from lipopolysaccharideinduced sickness in aged mice. J Nutr. 2005;135:1157-63.
    • (2005) J Nutr , vol.135 , pp. 1157-1163
    • Berg, B.M.1    Godbout, J.P.2    Chen, J.3    Kelley, K.W.4    Johnson, R.W.5
  • 42
    • 0020020919 scopus 로고
    • Iron requirements of baby pigs reared in germ-free or conventional environments on a condensed milk diet
    • Miller ER, Waxler GL, Ku PK, Ullrey DE, Whitehair CK. Iron requirements of baby pigs reared in germ-free or conventional environments on a condensed milk diet. J Anim Sci. 1982;54:106-15.
    • (1982) J Anim Sci , vol.54 , pp. 106-115
    • Miller, E.R.1    Waxler, G.L.2    Ku, P.K.3    Ullrey, D.E.4    Whitehair, C.K.5
  • 44
    • 0015302847 scopus 로고
    • Plasma iron and total iron-binding capacity in piglets in anemia and iron administration
    • Furugouri K. Plasma iron and total iron-binding capacity in piglets in anemia and iron administration. J Anim Sci. 1972;34:421-6.
    • (1972) J Anim Sci , vol.34 , pp. 421-426
    • Furugouri, K.1
  • 45
    • 84870509086 scopus 로고    scopus 로고
    • Association of level of GFR with complications in adults [cited 23 May 2012]. Available from
    • Foundation NK. Association of level of GFR with complications in adults [cited 23 May 2012]. Available from: http://www.kidney.org.
    • Foundation, N.K.1
  • 46
    • 33846461062 scopus 로고    scopus 로고
    • Morris water maze: procedures for assessing spatial and related forms of learning and memory
    • Vorhees CV, Williams MT. Morris water maze: procedures for assessing spatial and related forms of learning and memory. Nat Protoc. 2006;1:848-58.
    • (2006) Nat Protoc , vol.1 , pp. 848-858
    • Vorhees, C.V.1    Williams, M.T.2
  • 47
    • 0022548184 scopus 로고
    • Brain iron-deficiency causes reduced learning capacity in rats
    • Yehuda S, Youdim ME, Mostofsky DI. Brain iron-deficiency causes reduced learning capacity in rats. Pharmacol Biochem Behav. 1986;25: 141-4.
    • (1986) Pharmacol Biochem Behav , vol.25 , pp. 141-144
    • Yehuda, S.1    Youdim, M.E.2    Mostofsky, D.I.3
  • 48
    • 0003667212 scopus 로고    scopus 로고
    • Attention-deficit/hyperactivity disorder (ADHD) in children
    • Mayo Clinic; 2011 [cited 2012 May 23]. Available from
    • Attention-deficit/hyperactivity disorder (ADHD) in children. Mayo Clinic; 2011 [cited 2012 May 23]. Available from: http://www. mayoclinic.com.
  • 50
    • 84869104570 scopus 로고    scopus 로고
    • The effects of brain iron deficiency on cognitive and behavioral aspects
    • Yehuda S, Mostofsky DI, editors. New York: Humana Press
    • Yehuda S, Rabinovitz S, Carasso RL, Mostofsky DI. The effects of brain iron deficiency on cognitive and behavioral aspects. In: Yehuda S, Mostofsky DI, editors. Iron deficiency and overload. New York: Humana Press; 2010. p. 195-206.
    • (2010) Iron deficiency and overload , pp. 195-206
    • Yehuda, S.1    Rabinovitz, S.2    Carasso, R.L.3    Mostofsky, D.I.4
  • 51
    • 0020837860 scopus 로고
    • The role of dopamine in locomotor activity and learning
    • Beninger RJ. The role of dopamine in locomotor activity and learning. Brain Res. 1983;287:173-96.
    • (1983) Brain Res , vol.287 , pp. 173-196
    • Beninger, R.J.1
  • 53
    • 84863784294 scopus 로고    scopus 로고
    • Temporal manipulation of transferrin-receptor-1-dependent iron uptake identifies a sensitive period in mouse hippocampal neurodevelopment
    • Fretham SJB, Carlson ES, Wobken J, Tran PV, Petryk A, Georgieff MK. Temporal manipulation of transferrin-receptor-1-dependent iron uptake identifies a sensitive period in mouse hippocampal neurodevelopment. Hippocampus. 2012:22:1691-702.
    • (2012) Hippocampus , vol.22 , pp. 1691-1702
    • Fretham, S.J.B.1    Carlson, E.S.2    Wobken, J.3    Tran, P.V.4    Petryk, A.5    Georgieff, M.K.6
  • 54
    • 58449119697 scopus 로고    scopus 로고
    • A developmental cognitive neuroscience approach to the study of atypical development: a model system involving infants of diabetic mothers
    • Coch D, Dawson G, Fischer KW, editors. New York: Guilford Press
    • Nelson CA. A developmental cognitive neuroscience approach to the study of atypical development: a model system involving infants of diabetic mothers. In: Coch D, Dawson G, Fischer KW, editors. Human behavior, learning and the developing brain. New York: Guilford Press; 2007. p. 1-27.
    • (2007) Human behavior, learning and the developing brain , pp. 1-27
    • Nelson, C.A.1
  • 55
    • 0017254488 scopus 로고
    • The effect of a low protein diet on the anatomical development of the rat brain
    • West CD, Kemper TL. The effect of a low protein diet on the anatomical development of the rat brain. Brain Res. 1976;107:221-37.
    • (1976) Brain Res , vol.107 , pp. 221-237
    • West, C.D.1    Kemper, T.L.2
  • 56
    • 0020338405 scopus 로고
    • Purification of a new neurotrophic factor from mammalian brain
    • Barde YA, Edgar D, Thoenen H. Purification of a new neurotrophic factor from mammalian brain. EMBO J. 1982;1:549-53.
    • (1982) EMBO J , vol.1 , pp. 549-553
    • Barde, Y.A.1    Edgar, D.2    Thoenen, H.3
  • 58
    • 65249121931 scopus 로고    scopus 로고
    • Critical role of promoter IV-driven BDNF transcription in GABAergic transmission and synaptic plasticity in the prefrontal cortex
    • Sakata K, Woo NH, Martinowich K, Greene JS, Schloesser RJ, Shen L, Lu B. Critical role of promoter IV-driven BDNF transcription in GABAergic transmission and synaptic plasticity in the prefrontal cortex. Proc Natl Acad Sci USA. 2009;106:5942-7.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 5942-5947
    • Sakata, K.1    Woo, N.H.2    Martinowich, K.3    Greene, J.S.4    Schloesser, R.J.5    Shen, L.6    Lu, B.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.