Control of leakage activities of alamethicin analogs by metals: Side chain-dependent adverse gating response to Zn2+

Bioorganic and Medicinal Chemistry

Volumn 20, Issue 23, 2012, Pages 6870-6876

  Noshiro, Daisuke ^a   Asami, Koji ^a   Futaki, Shiroh ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Aminoisobutyric acid (Aib); Alamethicin; Histidine; Leakage assay; Zn2+ coordination

Indexed keywords

2 AMINO 2 METHYLPROPIONIC ACID; ALAMETHICIN DERIVATIVE; GLYCINE; HISTIDINE; LEUCINE; LIPOSOME; METAL; NORLEUCINE; NORVALINE; ZINC ION;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; CHANNEL GATING; MEMBRANE PERMEABILITY; PEPTIDE SYNTHESIS; PROTEIN STRUCTURE; STRUCTURE ACTIVITY RELATION;

ALAMETHICIN; AMINO ACID SEQUENCE; ANTI-BACTERIAL AGENTS; CIRCULAR DICHROISM; IONOPHORES; LIPOSOMES; MOLECULAR SEQUENCE DATA; ZINC;

EID: 84869097238     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2012.09.046     Document Type: Article

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