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Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 23, 2012, Pages 7036-7040

Novel series of 3-amino-N-(4-aryl-1,1-dioxothian-4-yl)butanamides as potent and selective dipeptidyl peptidase IV inhibitors

(8) Nitta, Aiko a Fujii, Hideaki a Sakami, Satoshi a Satoh, Mikiya a Nakaki, Junko a Satoh, Shiho a Kumagai, Hiroki a Kawai, Hideki a

a TORAY INDUSTRIES INC (Japan)

Author keywords

Diabetes; Dipeptidyl peptidase IV; Inhibitor

Indexed keywords

3 AMINO N(4 ARYL 1,1 DIOXOTHIAN 4 YL)BUTANAMIDE; 3 AMINO N[4 (4 PHENYLTHIAZOL 2 YL)TETRAHYDRO 2H THIOPYRAN 4 YL) 4 (2,4,5 TRIFLUOROPHENYL)BUTANAMIDE 1,1 DIOXIDE; DIPEPTIDYL PEPTIDASE IV INHIBITOR; PEPTIDE HYDROLASE INHIBITOR; UNCLASSIFIED DRUG;

ACYLATION; ARTICLE; ENZYME INHIBITION; GLUCOSE BLOOD LEVEL; HUMAN; ORAL GLUCOSE TOLERANCE TEST;

ADMINISTRATION, ORAL; AMIDES; ANIMALS; BLOOD GLUCOSE; CACO-2 CELLS; DIPEPTIDYL PEPTIDASE 4; DIPEPTIDYL-PEPTIDASE IV INHIBITORS; GLUCOSE TOLERANCE TEST; HUMANS; MICE; MICE, INBRED ICR; PROTEIN BINDING; PYRANS; THIAZOLES;

EID: 84869097087 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2012.09.099 Document Type: Article

Times cited : (22)

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