An Introduction to Drug Discrimination

Drug Discrimination: Applications to Medicinal Chemistry and Drug Studies

Volumn , Issue , 2011, Pages 3-17

  Glennon, Richard A ^a   Young, Richard ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

Discriminable stimuli differentiation; Drug discrimination paradigm; Drug dose sensitivity

Indexed keywords

EID: 84869091351     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9781118023150.ch1     Document Type: Chapter

References (29)

1. Young , R. , Rosecrans , J.A. , Glennon , R.A. ( 1983 ). Behavioral effects of 5-methoxy-N , N-dimethyltryptamine and dose-dependent antagonism by BC-105 . Psychopharmacology , 80 , 156-160 .
2. Appel , J.B. , White , P.J. , West , K.S. , Holohean , A.M. ( 1982 ). Discriminative stimulus properties of ergot alkaloids . In: Colpaert , F.C. and Slangen , J.L. , Eds. Drug Discrimination: Applications to CNS Pharmacology . Elsevier Biomedical Press , Amsterdam , pp 49-67 .
3. Merlin , M.D. ( 2003 ). Archaeological evidence for the tradition of psychoactive plant use in the old world . Economic Botany , 57 , 295-323 .
4. Beecher , H. K. ( 1959 ). Measurement of Subjective Responses: Quantitative Effects of Drugs . Oxford University Press , New York .
5. Jasinski , D.R. , Johnson , R.E. , Henningfield , J.E. ( 1984 ). Abuse liability assessment in human subjects . Trends in Pharmacological Sciences , 5 , 196-200 .
6. Haertzen , C.A. ( 1965 ). Addiction Research Center Inventory (ARCI): development of a general drug estimation scale . The Journal of Nervous and Mental Disease , 141 , 300-307 .
7. Haertzen , C. ( 1966 ). Development of scales based on patterns of drug effects, using the addicition research center inventory (ARCI) . Psychological Reports , 18 , 163-194 .
8. Haertzen , C.A. , Hickey , J.E. ( 1987 ). Addiction Research Center Inventory (ARCI): measurement of euphoria and other drug effects . In: M.A. Bozarth , Ed. Methods for Assessing the Reinforcing Properties of Abused Drugs . Springer-Verlag , New York .
9. De Wit , H. , Griffiths , R.R. ( 1991 ). Testing the abuse liability of anxiolytic and hypnotic drugs in humans . Drug and Alcohol Dependence , 28 , 83-111 .
10. Foltin , R.W. , Fischman , M.W. ( 1991 ). Assessment of abuse liability of stimulant drugs in humans: a methodological survey . Drug and Alcohol Dependence , 28 , 3-48 .
11. McNair , D.M. , Lorr , M. , Droppleman , L.F. ( 1971 ). Manual for the Profile of Mood States . Educational and Industrial Testing Service , San Diego .
12. Fraser , H.F. , Van Horn , G.D. , Martin , W.R. , Wolbach , A.B. , Isbell , H. ( 1961 ). Methods for evaluating addiction liability. (A) " Attitude " of opiate addicts toward opiate-like drugs. (B) A short-term " direct " addiction test . Journal of Pharmacology and Experimental Therapeutics , 133 , 371-387 .
13. Jasinski , D.R. ( 1977 ). Assessment of the abuse potential of morphine-like drugs (methods used in man ). In: Martin W.R. , Ed. Drug Addiction I . Springer-Verlag , Heidelberg .
14. Colpaert , F.C. ( 1982 ). Increased naloxone reversibility in fentanyl dose-dose discrimination . Eurpean Journal of Pharmacology , 84 , 229-231 .
15. Colpaert , F.C. , Janssen , P.A. ( 1982 ). OR discrimination: a new drug discrimination method . European Journal of Pharmacology , 78 , 141-144 .
16. Stolerman , I.P. , Mariathasan , E.A. , White , J.A. , Olufsen , K.S. ( 1999 ). Drug mixtures and ethanol as compound internal stimuli . Pharmacology Biochemistry and Behavior , 64 , 221-228 .
17. Colpaert , F.C. , Niemegeers , C.J. , Janssen , P.A. ( 1975 ). Differential response control by isopropamide: a peripherally induced discriminative cue . European Journal of Pharmacology , 34 , 381-384 .
18. Koob , G.F. , Weiss , F. ( 1990 ). Pharmacology of drug self-administration . Alcohol , 7 , 193-197 .
19. Bardo , M.T. , Bevins , R.A. ( 2000 ). Conditioned place preference: what does it add to our preclinical understanding of drug reward? Psychopharmacology , 153 , 31-43 .
20. Stolerman , I.P. ( 1993 ). Components of drug dependence: reinforcement, discrimination and adaptation . Biochemical Society Symposium , 59 , 1-12 .
21. Glennon , R.A. , Young , R. , Benington , F. , Morin , R.D. ( 1982 ). Behavioral and serotonin receptor properties of 4-substituted derivatives of the hallucinogen 1-(2,5-dimethoxyphenyl)-2-aminopropane . Journal of Medicinal Chemistry , 25 , 1163-1168 .
22. Glennon , R.A. ( 1992 ). Animal models for assessing hallucinogenic agents . In: A. , Boulton , G. , Baker , P.H. Wu , Eds. Models of Drug Addiction . Humana Press , Totowa , pp 345-381 .
23. Schechter , M.D. , Signs , S.A. , Boja , J.W. ( 1989 ). Stability of the stimulus properties of drugs over time . Pharmacology, Biochemistry, and Behavior , 32 , 361-364 .
24. Gianutsos , G. , Lal , H. ( 1976 ). Selective interaction of drugs with a discriminable stimulus associated with narcotic action . Life Sciences , 19 , 91-98 .
25. Shannon , H.E. , Holtzman , S.G. ( 1979 ). Morphine training dose: a determinant of stimulus generalization to narcotic antagonists in the rat . Psychopharmacology , 61 , 239-244 .
26. Krynock , G.M. , Rosecrans , J.A. ( 1979 ). Morphine as a discriminative stimulus: role of periaqueductal gray neurons . Research Communications in Chemical Pathology and Pharmacology , 23 , 49-60 .
27. Greenberg , I. , Kuhn , D.M. , Appel , J.B. ( 1975 ). Behaviorally induced sensitivity to the discriminable properties of LSD . Psychopharmacologia , 43 , 229-232 .
28. Overton , D.A. ( 1979 ). Drug discrimination training with progressively lowered doses . Science , 205 , 720-721 .
29. White , F.J. , Appel , J.B. ( 1982 ). Training dose as a factor in LSD-saline discrimination . Psychopharmacology , 76 , 20-25 .