Pharmacokinetics of intravenous ketorolac following caesarean delivery

International Journal of Obstetric Anesthesia

Volumn 21, Issue 4, 2012, Pages 334-338

  Kulo, A ^a   Van De Velde, M ^a   Van Calsteren, K ^a   Smits, A ^a   De Hoon, J ^a   Verbesselt, R ^a   Deprest, J ^a   Allegaert, K ^a  

^a UNIVERSITY HOSPITALS LEUVEN   (Belgium)

Author keywords

Caesarean delivery; Ketorolac; Pharmacokinetics; Postoperative pain; Postpartum; Pregnancy

Indexed keywords

KETOROLAC TROMETAMOL;

ADULT; ARTICLE; CESAREAN SECTION; CLINICAL ARTICLE; CONTROLLED STUDY; DISTRIBUTION VOLUME; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; FEMALE; FOLLOW UP; HUMAN; OBSTETRIC ANALGESIA; OPEN STUDY; PROSPECTIVE STUDY;

EID: 84869091000     PISSN: 0959289X     EISSN: 15323374     Source Type: Journal    
DOI: 10.1016/j.ijoa.2012.06.001     Document Type: Article

References (17)

1. Wu CL, Raja SN. Treatment of acute postoperative pain. Lancet 2011;377:2215-25.
2. McDonnell NJ, Keating ML, Muchatuta NA, Pavy TJ, Paech MJ. Analgesia after caesarean delivery. Anaesth Intensive Care 2009;37:539-51.
3. Pan PH. Post cesarean delivery pain management: multimodal approach. Int J Obstet Anesth 2006;15:185-8.
4. Van den Anker JN. Is it safe to use opioids for obstetric pain while breastfeeding? J Pediatr 2012;160:4-6.
5. White PF, Raeder J, Kehlet H. Ketorolac: its role as part of multimodal analgesic regimen. Anesth Analg 2012;114:250-4.
6. Pavy TJ, Paech MJ, Evans SF. The effect of intravenous ketorolac on opioid requirement and pain after cesarean delivery. Anesth Analg 2001;92:1010-4.
7. Dahl V, Hagen IE, Sveen AM, Norseng H, Koss KS, Steen T. High-dose diclofenac for postoperative analgesia after elective caesarean section in regional anaesthesia. Int J Obstet Anesth 2002;11:91-4.
8. De Oliveira GS Jr, Agarwal D, Benzon HT. Perioperative single dose ketorolac to prevent postoperative pain: a meta-analysis of randomized trials. Anesth Analg 2012;114:424-33.
9. Feghali MN, Mattison DR. Clinical therapeutics during pregnancy. J Biomed Biotech 2011;2011:783528.
10. Wischnik A, Manth SM, Lloyd J, Bullingham R, Thompson JS. The excretion of ketorolac tromethamine into breast milk after multiple oral dosing. Eur J Clin Pharmacol 1989;36:521-4.
11. Kulo A, van de Velde M, de Hoon J, et al. Pharmacokinetics of a loading dose of intravenous paracetamol post caesarean delivery. Int J Obstet Anesth 2012;21:125-8.
12. Wang Z, Dsida RM, Avram MJ. Determination of ketorolac in human plasma by reversed-phase high-performance liquid chromatography using solid-phase extraction and ultraviolet detection. J Chromatogr B Biomed Sci Appl 2001;755:383-6.
13. El-Tahan MR, Warda OM, Yasseen AM, Attallah MM, Matter MK. A randomized study of the effects of preoperative ketorolac on general anaesthesia for caesarean section. Int J Obstet Anesth 2007;16:214-20.
14. Brocks DR, Jamali F. Clinical pharmacokinetics of ketorolac tromethamine. Clin Pharmacokinet 1992;23:415-27.
15. Gravenstein D, Suri A, Derendorf HC, Koska AJ. Influence of plasma expansion on plasma protein binding of ketorolac. J Clin Anesth 1998;10:464-8.
16. Allegaert K, van Mieghem T, Verbesselt R, et al. Cefazolin plasma protein binding saturability during pregnancy. Methods Find Exp Clin Pharmacol 2009;31:25-8.
17. Allegaert K, van Mieghem T, Verbesselt R, et al. Cefazolin pharmacokinetics in maternal plasma and amniotic fluid during pregnancy. Am J Obstet Gynecol 2009;200:170.e1-7.