Nitric oxide synthase (eNOS4a/b) gene polymorphism is associated with tumor recurrence and progression in superficial bladder cancer cases

Journal of Urology

Volumn 188, Issue 6, 2012, Pages 2398-2403

  Amasyali, Akin Soner ^a   Kucukgergin, Canan ^b   Erdem, Selcuk ^b   Sanli, Oner ^b   Seckin, Sule ^b   Nane, Ismet ^b  

^a ISTANBUL UNIVERSITY   (Turkey)

^b ISTANBUL UNIVERSITY   (Turkey)

Author keywords

carcinoma; genetic; nitric oxide synthase; polymorphism; urinary bladder; urothelium

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUTATHIONE; MALONALDEHYDE;

ADULT; ARTICLE; BLADDER CANCER; CANCER GRADING; CANCER GROWTH; CANCER RECURRENCE; CANCER RISK; CANCER STAGING; CARCINOMA IN SITU; CONTROLLED STUDY; FEMALE; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC RISK; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; MUSCLE METASTASIS; OXIDATIVE STRESS; POPULATION RESEARCH; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RECURRENCE RISK; SMOKING; SUPERFICIAL BLADDER CANCER;

AGED; CARCINOMA, TRANSITIONAL CELL; CASE-CONTROL STUDIES; CONFIDENCE INTERVALS; DISEASE PROGRESSION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; LOGISTIC MODELS; MALE; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE III; ODDS RATIO; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; PROGNOSIS; REFERENCE VALUES; RISK ASSESSMENT; STATISTICS, NONPARAMETRIC; SURVIVAL ANALYSIS; URINARY BLADDER NEOPLASMS;

EID: 84869090735     PISSN: 00225347     EISSN: 15273792     Source Type: Journal    
DOI: 10.1016/j.juro.2012.07.096     Document Type: Article

References (30)

1. S. Sharma, P. Ksheersagar, P. Sharma Diagnosis and treatment of bladder cancer Am Fam Physician 80 2009 717
2. B.W. Van Rhijn, T.C. Zuiverloon, A.N. Vis Molecular grade (FGFR3/MIB-1) and EORTC risk scores are predictive in primary non-muscle-invasive bladder cancer Eur Urol 58 2010 433
3. J.D. Burch, T.E. Rohan, G.R. Howe Risk of bladder cancer by source and type of tobacco exposure: a case-control study Int J Cancer 44 1989 622
4. S. Moncado, A. Higgs The L-arginine-nitric oxide pathway N Eng J Med 329 1993 2002
5. J. Chen, Y. Yan, J. Li Differential requirement of signal pathways for benzo[a]pyrene (B[a]P)-induced nitric oxide synthase (iNOS) in rat esophageal epithelial cells Carcinogenesis 26 2005 1035
6. O.T. Jansson, E. Morcos, L. Brundin The role of nitric oxide in bacillus Calmette-Guérin mediated anti-tumour effects in human bladder cancer Br J Cancer 78 1998 588
7. E. Morcos, O.T. Jansson, J. Adolfsson Endogenously formed nitric oxide modulates cell growth in bladder cancer cell lines Urology 53 1999 1252
8. S. Yoon, J. Moon, C. Shin Smoking status-dependent association of the 27-bp repeat polymorphism in intron 4 of endothelial nitric oxide synthase gene with plasma nitric oxide concentrations Clin Chim Acta 324 2002 113
9. T. Tsukada, K. Yokoyama, T. Arai Evidence of association of the ecNOS gene polymorphism with plasma NO metabolite levels in humans Biochem Biophys Res Commun 245 1998 190
10. L.T. Guey, M. García-Closas, C. Murta-Nascimento Genetic susceptibility to distinct bladder cancer subphenotypes Eur Urol 57 2010 283
11. M. Franekova, E. Halasova, E. Bukovska Gene polymorphisms in bladder cancer Urol Oncol 26 2008 1
12. G. Ghilardi, M.L. Biondi, F. Cecchini Vascular invasion in human breast cancer is correlated to T->786C polymorphism of NOS3 gene Nitric Oxide 9 2003 118
13. R. Medeiros, A. Morais, A. Vasconcelos Endothelial nitric oxide synthase gene polymorphisms and genetic susceptibility to prostate cancer Eur J Cancer Prev 11 2002 343
14. L.A. Hefler, C. Grimm, T. Lantzsch Polymorphisms of the endothelial nitric oxide synthase gene in breast cancer Breast Cancer Res Treat 98 2006 151
15. L.A. Hefler, E. Ludwig, D. Lampe Polymorphisms of the endothelial nitric oxide synthase gene in ovarian cancer Gynecol Oncol 86 2002 134
16. E.K. Riener, L.A. Hefler, C. Grimm Polymorphisms of the endothelial nitric oxide synthase gene in women with vulvar cancer Gynecol Oncol 93 2004 686
17. S.A. Miller, D.D. Dykes, H.S. Polesky A simple salting-out procedure for extracting DNA from human nucleated cells Nucleic Acids Res 16 1988 1215
18. X.L. Wang, A.S. Sim, R.F. Badenhop A smoking-dependent risk of coronary artery disease associated with a polymorphism of the endothelial nitric oxide synthase gene Nat Med 2 1996 41
19. J.A. Buege, S.D. Aust Microsomal lipid peroxidation Methods Enzymol 52 1978 302
20. E. Beutler, O. Duron, B.M. Kelly Improved method for the determination of blood glutathione J Lab Clin Med 61 1963 882
21. Y.T. Chen, C.L. Chen, H.W. Chen Discovery of novel bladder cancer biomarkers by comparative urine proteomics using iTRAQ technology J Proteome Res 9 2010 5803
22. K. Schawmborn, N.T. Gaisa, C. Henkel Tissue and serum proteomic profiling for diagnostic and prognostic bladder cancer markers Expert Rev Proteomics 7 2010 897
23. I. Proctor, K. Stoeber, G.H. Williams Biomarkers in bladder cancer Histopathology 57 2010 1
24. A. Blanes, J. Rubio, J.J. Sanchez-Carrillo Coexistent intraurothelial carcinoma and muscle-invasive urothelial carcinoma of the bladder: clonality and somatic down-regulation of DNA mismatch repair Hum Pathol 40 2009 988
25. C. Hafner, R. Knuechel, R. Stoehr Clonality of multifocal urothelial carcinomas: 10 years of molecular genetic studies Int J Cancer 101 2002 1
26. C.C. Yeh, R.M. Santella, L.L. Hsieh An intron 4 VNTR polymorphism of the endothelial nitric oxide synthase gene is associated with early onset colorectal cancer Int J Cancer 124 2009 1565
27. Y.H. Chien, D.T. Bau, K.Y. Jan Nitric oxide inhibits DNA-adduct excision in nucleotide excision repair Free Radic Biol Med 36 2004 1011
28. C. Ryk, G. Steineck, N.P. Wiklund The (CCTTT)n microsatellite polymorphism in the nitric oxide synthase 2 gene may influence bladder cancer pathogenesis J Urol 184 2010 2150
29. O. Sanli, C. Kucukgergin, M. Gokpinar Despite the lack of association between different genotypes and the presence of prostate cancer, endothelial nitric oxide synthase a/b (eNOS4a/b) polymorphism may be associated with advanced clinical stage and bone metastasis Urol Oncol 29 2009 467
30. L.A. Kiemeney Hereditary bladder cancer Scand J Urol Nephrol Suppl 218 2008 110