Capecitabine-induced chest pain relieved by diltiazem

American Journal of Cardiology

Volumn 110, Issue 11, 2012, Pages 1623-1626

  Ambrosy, Andrew P ^a   Kunz, Pamela L ^a   Fisher, George A ^a   Witteles, Ronald M ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CAPECITABINE; DILTIAZEM; TROPONIN;

ANUS CARCINOMA; ARTICLE; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CLINICAL ARTICLE; COLORECTAL CARCINOMA; DRUG WITHDRAWAL; DYSPNEA; ELECTROCARDIOGRAPHY; HUMAN; MULTIPLE CYCLE TREATMENT; PRIORITY JOURNAL; PROPHYLAXIS; ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; THORAX PAIN; TREATMENT PLANNING;

ADENOCARCINOMA; AGED; ANTIMETABOLITES, ANTINEOPLASTIC; ANUS NEOPLASMS; CALCIUM CHANNEL BLOCKERS; CARCINOMA, SQUAMOUS CELL; CHEST PAIN; COLORECTAL NEOPLASMS; CORONARY VASOSPASM; DEOXYCYTIDINE; DILTIAZEM; ELECTROCARDIOGRAPHY; FEMALE; FLUOROURACIL; FOLLOW-UP STUDIES; HUMANS; MALE; MIDDLE AGED; PRODRUGS; SECONDARY PREVENTION; TREATMENT OUTCOME;

EID: 84869089996     PISSN: 00029149     EISSN: 18791913     Source Type: Journal    
DOI: 10.1016/j.amjcard.2012.07.026     Document Type: Article

References (24)

1. M. Venturini Rational development of capecitabine Eur J Cancer 38 suppl 2002 3 9
2. P.M. Hoff, R. Ansari, G. Batist, J. Cox, W. Kocha, M. Kuperminc, J. Maroun, D. Walde, C. Weaver, E. Harrison, H.U. Burger, B. Osterwalder, A.O. Wong, R. Wong Comparison of oral capecitabine versus intravenous fluorouracil plus leucovorin as first-line treatment in 605 patients with metastatic colorectal cancer: results of a randomized phase III study J Clin Oncol 19 2001 2282 2292
3. E. Van Cutsem, C. Twelves, J. Cassidy, D. Allman, E. Bajetta, M. Boyer, R. Bugat, M. Findlay, S. Frings, M. Jahn, J. McKendrick, B. Osterwalder, G. Perez-Manga, R. Rosso, P. Rougier, W.H. Schmiegel, J.F. Seitz, P. Thompson, J.M. Vieitez, C. Weitzel, P. Harper Oral capecitabine compared with intravenous fluorouracil plus leucovorin in patients with metastatic colorectal cancer: results of a large phase III study J Clin Oncol 19 2001 4097 4106
4. E. Van Cutsem, M. Findlay, B. Osterwalder, W. Kocha, D. Dalley, R. Pazdur, J. Cassidy, L. Dirix, C. Twelves, D. Allman, J.F. Seitz, J. Scholmerich, H.U. Burger, J. Verweij Capecitabine, an oral fluoropyrimidine carbamate with substantial activity in advanced colorectal cancer: results of a randomized phase II study J Clin Oncol 18 2000 1337 1345
5. J.A. Oshaughnessy, J. Blum, V. Moiseyenko, S.E. Jones, D. Miles, D. Bell, R. Rosso, L. Mauriac, B. Osterwalder, H.U. Burger, S. Laws Randomized, open-label, phase II trial of oral capecitabine (Xeloda) vs. a reference arm of intravenous CMF (cyclophosphamide, methotrexate and 5-fluorouracil) as first-line therapy for advanced/metastatic breast cancer Ann Oncol 12 2001 1247 1254
6. J. Cassidy, C. Twelves, E. Van Cutsem, P. Hoff, E. Bajetta, M. Boyer, R. Bugat, U. Burger, A. Garin, U. Graeven, J. McKendric, J. Maroun, J. Marshall, B. Osterwalder, G. Perez-Manga, R. Rosso, P. Rougier, R.L. Schilsky First-line oral capecitabine therapy in metastatic colorectal cancer: a favorable safety profile compared with intravenous 5-fluorouracil/leucovorin Ann Oncol 13 2002 566 575
7. W. Scheithauer, J. McKendrick, S. Begbie, M. Borner, W.I. Burns, H.A. Burris, J. Cassidy, D. Jodrell, P. Koralewski, E.L. Levine, N. Marschner, J. Maroun, P. Garcia-Alfonso, J. Tujakowski, G. Van Hazel, A. Wong, J. Zaluski, C. Twelves Oral capecitabine as an alternative to i.v. 5-fluorouracil-based adjuvant therapy for colon cancer: safety results of a randomized, phase III trial Ann Oncol 14 2003 1735 1743
8. R. Sharma, L. Rivory, P. Beale, S. Ong, L. Horvath, S.J. Clarke A phase II study of fixed-dose capecitabine and assessment of predictors of toxicity in patients with advanced/metastatic colorectal cancer Br J Cancer 94 2006 964 968
9. J.L. Blum, S.E. Jones, A.U. Buzdar, P.M. LoRusso, I. Kuter, C. Vogel, B. Osterwalder, H.U. Burger, C.S. Brown, T. Griffin Multicenter phase II study of capecitabine in paclitaxel-refractory metastatic breast cancer J Clin Oncol 17 1999 485 493
10. B. Schnetzler, N. Popova, C. Collao Lamb, A.P. Sappino Coronary spasm induced by capecitabine Ann Oncol 12 2001 723 724
11. N. Frickhofen, F.J. Beck, B. Jung, H.G. Fuhr, H. Andrasch, M. Sigmund Capecitabine can induce acute coronary syndrome similar to 5-fluorouracil Ann Oncol 13 2002 797 801
12. A.A. Rizvi, P. Schauer, D. Owlia, J.E. Kallal Capecitabine-induced coronary vasospasm - a case report Angiology 55 2004 93 97
13. I.E. Kuppens, H. Boot, J.H. Beijnen, J.H. Schellens, J. Labadie Capecitabine induces severe angina-like chest pain Ann Intern Med 140 2004 494 495
14. S. Aksoy, B. Karaca, M. Dincer, S. Yalcin Common etiology of capecitabine and fluorouracil-induced coronary vasospasm in a colon cancer patient Ann Pharmacother 39 2005 573 574
15. A. Sestito, G.A. Sgueglia, C. Pozzo, A. Cassano, C. Barone, F. Crea, G.A. Lanza Coronary artery spasm induced by capecitabine J Cardiovasc Med (Hagerstown) 7 2006 136 138
16. C.A. Papadopoulos, H. Wilson Capecitabine-associated coronary vasospasm: a case report Emerg Med J 25 2008 307 309
17. L. Arbea, I. Coma-Canella, R. Martinez-Monge, J. Garcia-Foncillas A case of capecitabine-induced coronary microspasm in a patient with rectal cancer World J Gastroenterol 13 2007 2135 2137
18. Y.B. Goldsmith, N. Roistacher, M.S. Baum Capecitabine-induced coronary vasospasm J Clin Oncol 26 2008 3802 3804
19. S. Coughlin, S. Das, J. Lee, J. Cooper Capecitabine induced vasospastic angina Int J Cardiol 130 2008 e34 e36
20. A. Farina, C. Malafronte, M.A. Valsecchi, F. Achilli Capecitabine-induced cardiotoxicity: when to suspect? How to manage? A case report J Cardiovasc Med (Hagerstown) 10 2009 722 726
21. C. Lestuzzi, D. Crivellari, F. Rigo, E. Viel, N. Meneguzzo Capecitabine cardiac toxicity presenting as effort angina: a case report J Cardiovasc Med (Hagerstown) 11 2010 700 703
22. T. Stewart, N. Pavlakis, M. Ward Cardiotoxicity with 5-fluorouracil and capecitabine: more than just vasospastic angina Intern Med J 40 2010 303 307
23. S.S. Akhtar, K.P. Salim, Z.A. Bano Symptomatic cardiotoxicity with high-dose 5-fluorouracil infusion: a prospective study Oncology 50 1993 441 444
24. T. Sudhoff, M.D. Enderle, M. Pahlke, C. Petz, C. Teschendorf, U. Graeven, W. Schmiegel 5-Fluorouracil induces arterial vasocontractions Ann Oncol 15 2004 661 664