A new depsidone of Lobaria pulmonaria with acetylcholinesterase inhibition activity

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 28, Issue 4, 2013, Pages 876-878

  Pejin, Boris ^a,b,c   Tommonaro, Giuseppina ^a   Iodice, Carmine ^a   Tesevic, Vele ^b   Vajs, Vlatka ^d   De Rosa, Salvatore ^a  

^a CNR   (Italy)

^b UNIVERSITY OF BELGRADE   (Serbia)

^c UNIVERSITY OF BELGRADE   (Serbia)

^d UNIVERSITY OF BELGRADE   (Serbia)

Author keywords

Biological activity; Lichen; Secondary metabolite

Indexed keywords

ACETYLCHOLINESTERASE; CHOLINESTERASE INHIBITOR; DEPSIDONE; NATURAL PRODUCT; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG ISOLATION; DRUG SCREENING; DRUG STRUCTURE; ENZYME ACTIVITY; IN VITRO STUDY; LICHEN (ORGANISM); LOBARIA PULMONARIA; NONHUMAN; PRIORITY JOURNAL;

ACETYLCHOLINESTERASE; ASCOMYCOTA; CHOLINESTERASE INHIBITORS; DEPSIDES; ENZYME ACTIVATION; LACTONES; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84869076601     PISSN: 14756366     EISSN: 14756374     Source Type: Journal    
DOI: 10.3109/14756366.2012.677839     Document Type: Article

References (10)

1. Thomas H. Nash III. (2008). Lichen Biology. Cambridge University Press.
2. Neamati N, Hong H, Mazumder A, Wang S, Sunder S, Nicklaus MC et al. Depsides and depsidones as inhibitors of HIV-1 integrase: Discovery of novel inhibitors through 3D database searching. J Med Chem 1997;40:942-951.
3. Pejin B, Iodice C, Tommonaro G, De Rosa S. Synthesis and biological activities of thio-avarol derivatives. J Nat Prod 2008;71:1850-1853.
4. Gonzáles AG, Bermejo Barrera J, Rodríguez Pérez EM, Hernández Padrón CE. Depsidones from Lobaria pulmonaria and their chemotaxonomic importance. Biochem System Ecol 1994;22:583-586.
5. Culberson CF. Chemical studies in the genus Lobaria and the occurrence of a new tridepside, 4-O-methylgyrophoric acid. The Bryologist 1969;72:19-27.
6. Marston A, Kissling J, Hostettmann K. A rapid TLC bioautographic method for the detection of acetylcholinesterase and butyrylcholinesterase inhibitors in plants. Phytochem Anal 2002;13:51-54.
7. Rhee IK, van de Meent M, Ingkaninan K, Verpoorte R. Screening for acetylcholinesterase inhibitors from Amaryllidaceae using silica gel thin-layer chromatography in combination with bioactivity staining. J Chromatogr A 2001;915:217-223.
8. Scott LJ, Goa KL. Galantamine: A review of its use in Alzheimer's disease. Drugs 2000;60:1095-1122.
9. Pejin B, Tommonaro G, Iodice C, Tesevic V, Vajs V. Acetylcholinesterase inhibition activity of acetylated depsidones from Lobaria pulmonaria. Nat Prod Res (In Press). DOI: 10.1080/14786419.2011.585989.
10. Pejin B, Tommonaro G, Iodice C, Tesevic V, Vajs V. Acetylcholinesterase inhibition activity of a mixture of methylated depsidones from the lichen Lobaria pulmonaria. Asian J Chem 2012;24:3261-3262.