Functionally Suppressive CD8 T Regulatory Cells Are Increased in Patients with Multiple Myeloma: A Cause for Immune Impairment

PLoS ONE

Volumn 7, Issue 11, 2012, Pages

  Muthu Raja, Karthick Raja ^a   Kubiczkova, Lenka ^a   Rihova, Lucie ^a   Piskacek, Martin ^a   Vsianska, Pavla ^a   Hezova, Renata ^a   Pour, Ludek ^b   Hajek, Roman ^a,b  

^a MASARYK UNIVERSITY   (Czech Republic)

^b UNIVERSITY HOSPITAL BRNO   (Czech Republic)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 10; TRANSCRIPTION FACTOR FOXP3;

ADULT; AGED; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CYTOKINE RELEASE; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOPATHOLOGY; IMMUNOPHENOTYPING; LYMPHOCYTE COUNT; LYMPHOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; MAJOR CLINICAL STUDY; MALE; MULTIPLE MYELOMA; REAL TIME POLYMERASE CHAIN REACTION; REGULATORY T LYMPHOCYTE; RNA ANALYSIS; RNA GENE; SUPPRESSOR CELL;

ADULT; AGED; AGED, 80 AND OVER; CASE-CONTROL STUDIES; CD8-POSITIVE T-LYMPHOCYTES; ELECTROPHORESIS, AGAR GEL; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; HUMANS; IMMUNOBLOTTING; INFLAMMATION; INTERFERON-GAMMA; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; LYMPHOCYTE COUNT; MALE; MIDDLE AGED; MULTIPLE MYELOMA; PHENOTYPE; POLYMERASE CHAIN REACTION; RNA, MESSENGER; T-LYMPHOCYTES, REGULATORY;

EID: 84869072398     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0049446     Document Type: Article

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